A5086255610- Pancreatic and Hepatic Oncology Research
- Neuroendocrine Tumor Research Advances
- Fungal Infections and Studies
- Antifungal resistance and susceptibility
- Pancreatitis Pathology and Treatment
- Gastric Cancer Management and Outcomes
- Cancer Genomics and Diagnostics
- Renal and related cancers
- HIV/AIDS oral health manifestations
- Ectopic Pregnancy Diagnosis and Management
- Gastrointestinal disorders and treatments
- Lung Cancer Research Studies
- Immunotherapy and Immune Responses
- Genomic variations and chromosomal abnormalities
- Complement system in diseases
- Gestational Trophoblastic Disease Studies
- Viral-associated cancers and disorders
- Ovarian cancer diagnosis and treatment
- Lymphoma Diagnosis and Treatment
- Neutropenia and Cancer Infections
- Liver Disease Diagnosis and Treatment
- Metastasis and carcinoma case studies
- Helicobacter pylori-related gastroenterology studies
- COVID-19 Clinical Research Studies
- Soft tissue tumors and treatment
New York University
2019-2025
Emory University Hospital
2024
Island Hospital
2022
Winthrop-University Hospital
1999-2019
All India Institute of Medical Sciences
2017
Rutgers, The State University of New Jersey
2007
Hy-Line (United States)
2007
Duke Medical Center
1997-2003
Duke University Hospital
1997-2003
Maimonides Medical Center
1999-2002
It has been proposed that successful pregnancy is a T helper 2-type phenomenon, and (Th)1-type reactivity deleterious to pregnancy. The objective of this study was compare the concentrations Th1 Th2 cytokines produced by peripheral blood mononuclear cells from women undergoing unexplained recurrent spontaneous abortion (RSA) with those during normal at similar gestational stage. control group consisted 24 history pregnancies comprised 23 RSA. Blood obtained end first trimester as age...
Pancreatic ductal adenocarcinoma (PDAC) has prominent extracellular matrix (ECM) that compromises treatments yet cannot be nonselectively disrupted without adverse consequences. ECM of PDAC, despite the recognition its importance, not been comprehensively studied in patients. In this study, we used quantitative mass spectrometry (MS)-based proteomics to characterize proteins normal pancreas and pancreatic intraepithelial neoplasia (PanIN)- PDAC-bearing from both human patients mouse genetic...
Histoplasmosis is a common opportunistic infection in patients with human immunodeficiency virus (HIV) who reside areas where Histoplasma capsulatum endemic. We undertook prospective study of cohort 304 HIV-infected Kansas City from October 1990 through March 1993 to define the incidence-specific risk factors, and pathophysiology histoplasmosis. The annual incidence histoplasmosis was 4.7%; 74% were symptomatic (all whom had disseminated disease). A history exposure chicken coops, positive...
The lipooligosaccharides (LOS) of nontypable Haemophilus influenzae are an antigenically heterogeneous group macromolecules. Immunodiffusion and enzyme-linked immunosorbent assay inhibition studies with phenol-water-extracted LOS absorbed antisera specific for the oligosaccharide portion identified six strain-specific antigens. To facilitate screening large numbers strains to search antigenic heterogeneity, a system utilizing proteinase K whole cell digests in Western blots was developed....
Neoadjuvant therapy (NAT) is increasingly being used for pancreatic ductal adenocarcinoma (PDAC). This study investigates how NAT differentially impacts PDAC's carcinoma cells and the tumor microenvironment (TME). Spatial transcriptomics was to compare gene expression profiles in TME of 23 NAT-treated versus 13 NAT-naïve PDACs. Findings were validated by single-nucleus RNA sequencing (snRNA-seq) analysis. induces apoptosis inhibits proliferation coordinately upregulates multiple complement...
A 34-year-old male prisoner with a history of intravenous drug abuse presented fever, lymphadenopathy, weight loss, and recent onset congestive heart failure. Serologic testing was positive for antibodies to human immune deficiency virus. There intense myocardial uptake gallium. Autopsy showed primary immunoblastic lymphoma involving only the myocardium. While cardiac is an extremely rare condition, incidence may be higher in patients acquired syndrome (AIDS) should suspected cases atypical...
In areas where Histoplasma capsulatum infections are endemic in the United States, there is an increasing frequency of progressive disseminated histoplasmosis (PDH) as opportunistic infection patients with acquired immune deficiency syndrome (AIDS). The bone marrow and peripheral blood (PB) specimens 13 AIDS PDH were reviewed. Anemia, leukopenia, thrombocytopenia found 12, 10, 7 patients, respectively. Circulating organisms detected smears or buffy coat preparations from five associated PB...
Cesarean scar pregnancies (CSPs) are a relatively rare form of ectopic pregnancy in which the embryo is implanted within fibrous previous cesarean section. A greater number cases CSPs currently being reported as rates section increasing globally and detection has improved with use transvaginal ultrasound (TVUS) color Doppler imaging. Delayed diagnosis management this potentially life-threatening condition may result complications, predominantly uterine rupture hemorrhage significant...
Endoscopic ultrasound (EUS) is the most sensitive imaging modality for solid pancreatic lesions. The specificity, however, low (about 75%). It can be increased to 100% with an accuracy of 95% by addition fine-needle aspiration (FNA). Cytopathology plays important role. final diagnosis based upon correlation clinical, EUS, and cytologic features. A close interaction cytopathologist required in improving diagnostic yield. In this paper, we present overview role EUS-guided FNA importance...
Background Endoscopic ultrasound (EUS) guided fine‐needle aspiration (FNA) plays an important role in the diagnosis of various lesions. We sought to determine factors that influence diagnostic yield EUS–FNA, specifically, presence a cytopathologist, FNA site, and endoscopist's skill. Methods The data on cytopathologist's availability, duration procedure, number passes made, material for cell block (CB) preparation was collected over 18 months period. Results 230 specimens (218 patients) were...
The bioMérieux VITAL automated blood culture system measures a decrease in fluorescence to detect the presence of microorganisms blood. To assess performance with AER aerobic medium versus that nonradiometric BACTEC NR-660 PEDS PLUS for detection sepsis children, total 12,146 specimens were collected at three university medical centers and inoculated into bottles weighed before after filling. sample volumes considered adequate 6,276 bottle pairs. yield isolates was 629, which 489 (78%)...