- Anesthesia and Sedative Agents
- Airway Management and Intubation Techniques
- Anesthesia and Neurotoxicity Research
- Anesthesia and Pain Management
- Tracheal and airway disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Pediatric Pain Management Techniques
- Pharmaceutical studies and practices
- Intraoperative Neuromonitoring and Anesthetic Effects
- Epilepsy research and treatment
- Intraocular Surgery and Lenses
- Respiratory Support and Mechanisms
- Antibiotics Pharmacokinetics and Efficacy
- Adrenal Hormones and Disorders
- Pain Management and Opioid Use
- Spine and Intervertebral Disc Pathology
- Platelet Disorders and Treatments
- Treatment of Major Depression
- Electrical and Bioimpedance Tomography
- Chemistry and Chemical Engineering
- Neurosurgical Procedures and Complications
- Dermatology and Skin Diseases
- Acute Myocardial Infarction Research
- Emergency and Acute Care Studies
- Advanced MRI Techniques and Applications
British Columbia Children's Hospital
2008-2024
University of British Columbia
2006-2024
Children's Research Hospital
2017
Children's Hospital
2017
University of Alberta
2004-2007
University of Alberta Hospital
2003-2005
Alberta Hospital Edmonton
2003-2005
Boston Children's Hospital
2005
Heritage Foundation
2004
Arrow International (United States)
2004
In Brief this case series, we evaluated the incidence of laryngospasm using a clearly defined awake tracheal extubation technique in 20 children undergoing elective tonsillectomy with or without adenoidectomy. This required patients to be turned recovery position at end procedure before discontinuing volatile anesthetics. No further stimulation, besides continuous oximetry monitoring, was allowed until spontaneously woke up ("no touch" technique). The laryngospasm, oxygen saturation, and...
Inhalational anesthesia with spontaneous respiration is traditionally used to facilitate airway endoscopy in children. The potential difficulties maintaining adequate depth of using inhalational and the anesthetic pollution surgical environment are significant disadvantages this technique. We report our institutional experience total intravenous (TIVA) respiration.We prospectively studied 41 pediatric patients undergoing 52 endoscopies surgeries. Following induction anesthesia, a propofol...
HEPARIN-INDUCED thrombocytopenia (HIT) is an infrequent complication of heparin therapy. 1 A unique problem arises in patients with HIT who need anticoagulation, especially if urgent cardiac surgery planned. We report a case infant which Argatroban (GlaxoSmithKline, Middlesex, UK) was used as anticoagulant during cardiopulmonary bypass (CPB) and the unsuccessful use recombinant activated factor VII (rF-VIIa) to reverse effects postoperatively.
Summary Background: Maintaining spontaneous ventilation in children, using total intravenous anesthesia (TIVA), is often desirable, particularly for airway endoscopy. The aim of this study was to evaluate the effect age on dose remifentanil tolerated during under maintained with infusions propofol and provide guidelines administration maintain children. Methods: Forty‐five children scheduled strabismus surgery were divided by into three groups (group I: 6 months–3 years, group II: 3 years–6...
A 2.8-year-old female patient (11.6 kg) was admitted to the hospital for uncontrolled pain and swelling in left leg relating a metastatic neuroblastoma. Initially, her managed with oral morphine 2 mg (approx. 0.2 mg/kg) every 4 hours. Because she quite somnolent but still significant pain, analgesia then changed methadone 1 orally 6 hours (approximately 0.1 mg/kg/dose) eventually increased over 36 mg/kg/dose). She received 0.6 0.05 as needed breakthrough pain. continued have severe...
This study aimed to determine the age-specific bolus dose of remifentanil (ED(50)) facilitate tracheal intubation without use neuromuscular blocking agents.ASA 1-2 subjects were recruited into three groups 0-3 months (group I), 4-12 II), and 1-3 years III) age. A sequential up-and-down design determined dose, which was initially started at 3 mcg x kg(-1) adjusted in 1 increments (range 1-6 kg(-1)). Following pretreatment with glycopyrrolate 10 microg an induction propofol 5 mg kg(-1),...
In this case report, we describe the use of cerebrospinal fluid lavage as a successful treatment an inadvertent intrathecally placed epidural catheter in 14-yr-old girl who underwent combination anesthesia and general for orthopedic surgery. case, large amount local anesthetic was injected (the total possible intrathecal injection 200 mg lidocaine 61 bupivacaine), resulting apnea fixed dilated pupils patient at end Twenty milliliters replaced with 10 mL normal saline lactated Ringer's...
Summary In this prospective observational study we investigated the changes in cardiac index and mean arterial pressure children when positioned prone for scoliosis correction surgery. Thirty (ASA 1–2, aged 13–18 years) undergoing primary, idiopathic repair were recruited. The blood (median (IQR [range])) 2.7 (2.3–3.1 [1.4–3.7]) l.min −1 .m −2 73 (66–80 [54–91]) mmHg, respectively, at baseline; 2.9 (2.5–3.2 [1.7–4.4]) (63–81 [51–96]) mmHg following a 5‐ml.kg fluid bolus; 2.5 (2.2–2.7...
Dexmedetomidine is a useful anesthetic adjunct, increasingly popular during pediatric surgery and procedural sedation. Its half-life of 2-3 hours might prolong recovery discharge times when compared with an un-supplemented propofol anesthetic. This may create additional burden in busy post-anesthetic care unit (PACU).To investigate whether intraoperative adjuvant dexmedetomidine delays PACU patients undergoing anesthesia for day or investigations minimal anticipated post-procedural pain.We...
We report a series of 20 neonates and infants (18 born preterm) who underwent laparoscopic inguinal hernia repair with caudal anesthesia, oxygen via nasal cannula, intravenous anesthesia. Surgery was successful in all cases without airway instrumentation or intraoperative complications. Sedation provided dexmedetomidine, propofol, remifentanil. Two patients had apnea the following 24 hours. There were no unplanned intensive care admissions. Laparoscopy allowed bilateral 2 cases. Caudal...
Introduction Patient handover is a crucial transition requiring high level of coordination and communication. In the BC Children's Hospital (BCCH) pediatric intensive care unit (PICU), 10 adverse events stemming from issues that should have been addressed at operating room (OR) to PICU were reported into patient safety learning system (PSLS) within 1 year. We aimed undertake quality improvement project increase adherence standardized OR process 100% 6-month time frame. doing so, secondary...
Introduction: Maintaining spontaneous ventilation in children, using total intravenous anaesthesia, is often desirable, particularly for invasive airway procedures such as diagnostic endoscopy and removal of inhaled foreign bodies. The maximum tolerated infusion rate remifentanil during combination with a volatile anaesthetic (sevoflurane) has been studied children (1), where large dose variation was found. This also seemed to vary widely compared adults, who significantly less (2). Contrary...