Ajay D’Mello

ORCID: 0000-0003-1056-6828
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About
Contact & Profiles
Research Areas
  • Anesthesia and Sedative Agents
  • Intensive Care Unit Cognitive Disorders
  • Respiratory Support and Mechanisms
  • COVID-19 and healthcare impacts
  • Airway Management and Intubation Techniques
  • Cardiac Arrest and Resuscitation
  • Anesthesia and Neurotoxicity Research
  • Ultrasound in Clinical Applications
  • Intraoperative Neuromonitoring and Anesthetic Effects
  • Renal function and acid-base balance
  • Mitochondrial Function and Pathology
  • Genetics and Neurodevelopmental Disorders
  • Thermal Regulation in Medicine
  • Infection Control and Ventilation
  • Congenital Diaphragmatic Hernia Studies
  • Tracheal and airway disorders
  • Spine and Intervertebral Disc Pathology
  • Autism Spectrum Disorder Research
  • Poisoning and overdose treatments
  • Healthcare Decision-Making and Restraints
  • Esophageal and GI Pathology
  • Healthcare Technology and Patient Monitoring
  • Diet and metabolism studies
  • Spinal Hematomas and Complications
  • Nosocomial Infections in ICU

The Ohio State University
2017-2024

Nationwide Children's Hospital
2017-2024

Cincinnati Children's Hospital Medical Center
2015-2018

Cleveland Clinic
2014

Barro Colorado Island
2014

Sugammadex is a novel pharmacologic agent, which reverses neuromuscular blockade (NMB) via mechanism that differs completely from acetylcholinesterase inhibitors. By encapsulating rocuronium, sugammadex can provide recovery of function even when there profound degree NMB. We report anecdotal experience with the use to reverse NMB facilitate intraoperative neurophysiological monitoring (motor evoked potentials) in an adolescent scoliosis during posterior spinal fusion. Its potential...

10.4103/1658-354x.203024 article EN cc-by-nc-sa Saudi Journal of Anaesthesia 2017-01-01

We present a case of massive spinal epidural hematoma with an atypical presentation characterized by unilateral, isolated motor deficit in the right lower extremity on postoperative day 2 after Collis-Nissen fundoplication and T7-8 for pain. The had been placed preoperative theater before surgery. Subcutaneous unfractionated heparin was initiated 18 hours later 1 3 times daily dosing. patient also received doses ketorolac starting 10 placement. Symptoms were first reported 2, 37 Thoracic...

10.1213/xaa.0000000000000001 article EN A & A Case Reports 2014-04-01

Background: During intraoperative care, ventilatory parameters including peak inflating pressure (PIP) and exhaled tidal volumes are continuously monitored to assess changes in respiratory resistance compliance. Changes these parameters, such as an increase PIP or a decrease the volume, may indicate various pathologic processes that require immediate attention prevent inadequate ventilation resulting hypoxemia hypercarbia. A kinked endotracheal tube (ETT) mimic other bronchospasm, mainstem...

10.4103/sja.sja_15_24 article EN cc-by-nc-sa Saudi Journal of Anaesthesia 2024-06-04

The coronavirus disease 2019 (COVID-19) pandemic has led to a global surge in hospitalizations due pneumonia and respiratory distress. As with other infectious medical conditions, the perioperative care of patient an active or recent severe acute syndrome 2 (SARS-CoV-2) infection must address concerns regarding both healthcare providers patient. SARS-CoV-2-positive patients face higher risk pulmonary complications significantly rates mortality, especially those preoperative symptoms. We...

10.14740/ijcp541 article EN International Journal of Clinical Pediatrics 2024-12-01

ABSTRACT Introduction COVID‐19 increases anesthetic risk in children, but understanding of complication differences by symptom presence and severity is limited. We hypothesized that symptomatic COVID‐19+ especially with lower respiratory symptoms, would have higher perioperative complications than asymptomatic patients be all diagnosed < 6 days before anesthesia. Methods This single‐center, retrospective cohort study reviewed records children 18 years old undergoing surgery general...

10.1111/pan.15051 article EN cc-by-nc-nd Pediatric Anesthesia 2024-12-05

One of the many safety features modern day anesthesia machines is adjustable pressure limiting (APL) valve. This device regulates within circuit during manual ventilation with bag. We report an unusual case where a crack in APL valve allowed release from resulting ineffective bag-valve-mask infant. The appropriate steps to prevent such issues are reviewed, and algorithm quickly identify intraoperative problems presented.

10.1213/xaa.0000000000001045 article EN A&A Practice 2019-04-30

Kleefstra syndrome (KS) is an autosomal dominant disorder caused by a chromosomal deletion at 9q34.3 resulting in pathogenic variants of the gene that codes for enzyme, euchromatin histone methyltransferase 1 (EHMT1). KS rare, yet clinically relevant congenital anesthesiologists because its potential cardiac and craniofacial involvement. We present 3-month-old patient with who required anesthetic care diagnostic laryngoscopy rigid bronchoscopy. The end-organ effects are reviewed our presented.

10.1213/xaa.0000000000001222 article EN A&A Practice 2020-05-01
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