A5031787851- Epilepsy research and treatment
- Pharmacological Effects and Toxicity Studies
- Medical Imaging Techniques and Applications
- Glioma Diagnosis and Treatment
- Sarcoma Diagnosis and Treatment
- Medical Imaging and Pathology Studies
- Parathyroid Disorders and Treatments
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Dialysis and Renal Disease Management
- Pediatric Urology and Nephrology Studies
- Alzheimer's disease research and treatments
- Orthopedic Infections and Treatments
- Advanced MRI Techniques and Applications
- Radiopharmaceutical Chemistry and Applications
- Radiation Dose and Imaging
- Neurological and metabolic disorders
- Cutaneous Melanoma Detection and Management
- Breast Cancer Treatment Studies
- Neonatal and fetal brain pathology
- Dementia and Cognitive Impairment Research
- Autoimmune Neurological Disorders and Treatments
- Orthopaedic implants and arthroplasty
- Urological Disorders and Treatments
- Breast Lesions and Carcinomas
- Urologic and reproductive health conditions
Health Research Institute of the Balearic Islands
2015-2024
Hospital Universitario Son Espases
2015-2024
Universitat de les Illes Balears
2023-2024
Hospital Clínic de Barcelona
2006-2014
Centre National de la Recherche Scientifique
2014
Centre de Recherche en Neurosciences de Lyon
2014
Fondation Neurodis
2014
Centre d'Exploration et de Recherche Médicale par Emission de Positons
2014
Hospices Civils de Lyon
2014
Inserm
2014
A precise assessment of the drug-resistant epileptic pediatric population for surgical candidacy is often challenging, and to date there are no evidence-based guidelines presurgical identification epileptogenic zone. To evaluate usefulness radionuclide imaging techniques evaluation patients, we compared results video-electroencephalography (EEG), brain MR imaging, interictal SPECT, ictal subtraction SPECT coregistered (SISCOM), PET with <sup>18</sup>F-FDG. <b>Methods:</b> Fifty-four children...
Purpose: To validate the use of 18F-fluorodeoxyglucose–positron emission tomography/magnetic resonance imaging (FDG-PET/MRI) coregistration for epileptogenic zone detection in children with MRI nonlesional refractory epilepsy and to assess its ability guide a second interpretation studies. Methods: Thirty-one whose results were included prospectively. All patients underwent presurgical evaluation following standard protocol our unit, which FDG-PET FDG-PET/MRI coregistration. Cerebral areas...
Tuberous sclerosis complex (TSC) is often associated with cerebral tubers and medically intractable epilepsy. We reevaluated whether increased uptake of α-[(11) C]methyl-l-tryptophan (AMT) in tuber epileptogenicity.We included 12 patients (six male, 4-53 years old) TSC refractory seizures who were evaluated for epilepsy surgery our center, including video-electroencephalographic (EEG) monitoring, fluid-attenuated inversion recovery magnetic resonance imaging (FLAIR MRI), positron emission...
Several studies using 18F-fluorodeoxyglucose positron emission tomography (18F-FDG-PET) or diffusion tensor imaging (DTI) have found both temporal and extratemporal abnormalities in patients with mesial lobe epilepsy ipsilateral hippocampal sclerosis (MTLE-HS), but data are lacking about the findings of techniques same patients. We aimed to determine whether extent 18F-FDG-PET hypometabolism is related DTI abnormalities. Twenty-one MTLE-HS underwent comprehensive preoperative evaluation; 18...
Subtraction of Ictal SPECT Co-registered to MRI (SISCOM) is an imaging technique used localize the epileptogenic focus in patients with intractable partial epilepsy. The aim this study was determine accuracy registration algorithms involved SISCOM analysis using FocusDET, a new user-friendly application. To end, Monte Carlo simulation employed generate realistic studies. Simulated sinograms were reconstructed by Filtered BackProjection (FBP) algorithm and Ordered Subsets Expectation...
The purpose of our study was to evaluate the performance and clinical usefulness an automated injector system (AIS) that administers injection for ictal SPECT after calculating volume tracer be injected over time. <b>Methods:</b> To test AIS, repeated injections were performed at different times preparation. consisted 56 patients with drug-resistant, complex partial seizures. Tracer using in 27 manual (MI) remaining 29. Injection time (<i>T<sub>I</sub></i>) measured seconds from seizure...
Dysembryoplastic neuroepithelial tumors (DNTs) represent a prevalent cause of epileptogenic brain tumors, the natural evolution which is much more benign than that most gliomas. Previous studies have suggested [(11)C]methionine positron emission tomography (MET-PET) could help to distinguish DNTs from other and hence optimize management patients. Here, we reassessed diagnostic accuracy MET-PET for differentiation between DNT neoplasms in larger population.We conducted retrospective study 77...
The aim of this study was to validate a nomogram and scoring system predict non-sentinel lymph node status in breast cancer patients with sentinel (SLN) involvement. A total 516 underwent biopsy at our institution from January 2001 August 2006. prospective database used identify positive SLN examination who completion axillary dissection. 114 were identified. Memorial Sloan-Kettering Cancer Center (MSKCC) an axilla Paris (Hôpital Tenon) the probability having non-SLN One hundred fourteen...
We present a modified version of the SISCOM procedure that uses interictal PET instead SPECT for seizure onset zone localization. called this new nuclear imaging processing technique PISCOM (PET subtracted ictal coregistered with MRI).We retrospectively studied 23 patients (age range 4-61 years) medically refractory epilepsy who had undergone MRI, SPECT, and FDG been seizure-free at least 2 years after surgical treatment. images were reprocessed (rFDG PET) to assimilate features image...
[99mTc]-ciprofloxacin is a useful radiopharmaceutical for the detection of osteoarticular prosthesis infection. We report new preparation method based on use tartrate anion as an exchange ligand and tartaric acid source tartrate. An improved quality control procedure also reported that allows measuring level [99mTc]-tartrate present in preparation. Copyright © 2006 John Wiley & Sons, Ltd.
The treatment of malignant melanoma or sarcomas on a limb using extremity perfusion with tumour necrosis factor (TNF-alpha) and melphalan can result in high degree systemic toxicity if there is any leakage from the isolated blood territory into vascular territory. Leakage currently controlled by radiotracers heavy external probes procedure that requires continuous manual calculations. aim this work was to develop light, easily transportable system monitor controlling pool radioactivity...