Wei-Han Li

ORCID: 0000-0003-1092-2343
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Neurological Disease Mechanisms and Treatments
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Sports injuries and prevention
  • Shoulder Injury and Treatment
  • Mitochondrial Function and Pathology
  • Traditional Chinese Medicine Analysis
  • Enzyme function and inhibition
  • Foot and Ankle Surgery
  • Acute Ischemic Stroke Management
  • Healthcare and Venom Research
  • Virology and Viral Diseases
  • Stroke Rehabilitation and Recovery
  • Phytochemistry and Biological Activities
  • Metabolomics and Mass Spectrometry Studies
  • Diverse Approaches in Healthcare and Education Studies
  • Tendon Structure and Treatment
  • Traditional Chinese Medicine Studies
  • Nitric Oxide and Endothelin Effects
  • Curcumin's Biomedical Applications
  • Macrophage Migration Inhibitory Factor
  • Advanced Glycation End Products research
  • Viral Infections and Vectors
  • Alzheimer's disease research and treatments
  • Barrier Structure and Function Studies
  • Acupuncture Treatment Research Studies

Chinese Academy of Medical Sciences & Peking Union Medical College
2018-2024

University of Malaya
2022-2024

Guangzhou University of Chinese Medicine
2021

South China Normal University
2021

Guangzhou University
2018

National Cheng Kung University
2018

Neuroinflammation has been demonstrated to be linked with Parkinson's disease (PD), Alzheimer's disease, and cerebral ischemia. Our previous investigation had identified that kaempferol (KAE) exerted protective effects on cortex neuron injured by LPS. In this study, the possible mechanism of KAE striatal dopaminergic neurons induced LPS in mice were further investigated. The results showed improved injury, increased levels tyrosine hydroxylase (TH) postsynaptic density protein 95 (PSD95)...

10.3390/ijms20030491 article EN International Journal of Molecular Sciences 2019-01-24

Kaempferol has been reported to act as an anti-inflammatory agent in LPS-induced neuroinflammation vitro and vivo, but its role the inflammation after cerebral ischemia/reperfusion (I/R) is unclear. The present study was investigate effect of kaempferol on ischemic brain tissue explore mechanisms I/R rats. Cerebral rat model established by middle artery occlusion for 60 min following reperfusion. at doses 25, 50 100 mg/kg administered 7 days I/R. treatment significantly reduced infarct...

10.1016/j.brainres.2019.146361 article EN cc-by-nc-nd Brain Research 2019-08-01

Myricitrin, a bioactive and natural flavonoids, is well known for its anti-inflammatory antioxidant properties. However, the anti-neuroinflammation possible mechanism has not been fully elucidated. Therefore, present study was to investigate of neuroprotection in nigrostriatum LPS-stimulated mice. The results showed that myricitrin improved neuron injury raised expressions PSD-95 protein TH In addition, decreased production pro-inflammatory factors including IL-1β, IL-6 TNFα, level chemokine...

10.1016/j.jneuroim.2019.577049 article EN cc-by-nc-nd Journal of Neuroimmunology 2019-09-03

Alzheimer’s disease (AD) is the most common cause of dementia worldwide, posing a considerable economic burden to patients and society as whole. Exercise has been confirmed non-drug intervention method in related literature on AD. However, at present, there are still few bibliometric studies AD exercise research. In order fill gap, this paper aims intuitively analyze growth published from 1998 2021 using bibliometrics, providing historical insights for scientific research circles. The main...

10.3390/jcm11195903 article EN Journal of Clinical Medicine 2022-10-06

The publications on elbow pain (EP) in overhead sports are increasing. results of previous studies mostly focus the influence EP ball game and throwing sports. Thus, a bibliometric analysis these may show direction hot topics future research trends. purpose this study is to identify trends For methods, first step use main keywords 'Elbow pain' 'Overhead sport' merging auxiliary vocabulary reach relevant global between 1970 2022 Web Science (WoS) database. literature data set imported into...

10.3390/healthcare10112242 article EN Healthcare 2022-11-09

The molecular functions of betanodavirus non-structural protein B and its role in host cell survival remain unclear. In the present study, we examined roles specific nuclear targeting domains B1 localization as well effect on cycle survival. Red spotted grouper nervous necrosis virus (RGNNV) was detected GF-1 cells early 24 hours post-infection (hpi). Using an EYFP-B1 fusion construct, observed (up to 99%) at 48 hpi. mediated by two arginine-rich (B domain: 46RRSRR51; C 63RDKRPRR70) domain...

10.1038/s41598-018-21340-x article EN cc-by Scientific Reports 2018-02-09

To observe the clinical effect of thunder-fire moxibustion in treatment qi deficiency-induced fatigue breast cancer patients undergoing chemotherapy.Sixty chemotherapy were randomly divided into (Moxi) and conventional nursing (nursing) groups (n=30 each group). Patients Moxi group treated with applied to back part body from Pishu (BL 20) Qihaishu 24) on bilateral sides abdominal Zhongwan (CV 12) Guanyuan 4) for 30 min, once a day 14 days. health education care. The simple scale, traditional...

10.13702/j.1000-0607.107698 article EN PubMed 2018-02-25

Abstract The effects of IT and R.I.C.E. treatment on arm muscle performance in overhead athletes with elbow pain (EP) have been partially validated. However, there is a lack research evidence regarding the efficacy these two methods among swimmers EP. aim this study was to investigate trends differences main outcomes were time group interventions voluntary contraction (MVC). Sixty elite freestyle from Tianjin, China, voluntarily participated completed 10-week intervention program. Swimmers...

10.1038/s41598-024-54789-0 article EN cc-by Scientific Reports 2024-02-27

The aim of this study was to obtain quantitative data on elbow joint ROM in elite freestyle swimmers with EP China. Of the 50 recruited, 41 completed all measurements during dry-land swimming stroke simulations. Elbow angle, velocity, and acceleration were measured using inertial measurement units. RMSE/D calculated determine deviation. Joint angle (3.33 ∘–42.96 ∘), angular velocity (−364.15 245.69 ∘/s), (−7051.80 1465.35 ∘/s2) significantly different between critical pain healthy....

10.1080/02640414.2024.2340887 article EN Journal of Sports Sciences 2024-04-15

Elbow pain (EP) in overhead sports is a common phenomenon. Swimming classified as an sport, but lack of attention regarding EP swimming has created gap the knowledge around elite freestyle Tianjin, China. The purpose this study was to identify distribution and prevalence among swimmers methodology involved total 311 qualified participants who volunteered undertake all measurements. main findings showed that 183 had (accounting for 58.84% participants), with 147 slight 36 critical pain....

10.3390/healthcare11192612 article EN Healthcare 2023-09-22

Abstract Background : Depression has a high incidence among patients with breast cancer, but the relationship between depression and cancer-related physiological changes is not clear. Objectives To explore effect of T lymphocytes on cancer patient’s quality life. Methods This cross-sectional study. A total 93 were recruited, 46 whom underwent lymphocyte, cortisol, BDNF, TNF-α, IL-1β collection. We analysed correlation indicators in these participants constructed two intermediary structural...

10.21203/rs.3.rs-967907/v1 preprint EN cc-by Research Square (Research Square) 2021-10-18
Coming Soon ...