G Mardare

ORCID: 0000-0003-1099-809X
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Research Areas
  • Liver Disease Diagnosis and Treatment
  • Liver Disease and Transplantation
  • Drug-Induced Hepatotoxicity and Protection
  • Genetic factors in colorectal cancer
  • Cultural Heritage Materials Analysis
  • Gastric Cancer Management and Outcomes
  • Rheumatoid Arthritis Research and Therapies
  • Eosinophilic Esophagitis
  • Helicobacter pylori-related gastroenterology studies
  • Chemical synthesis and alkaloids
  • Colorectal Cancer Screening and Detection
  • Forensic Fingerprint Detection Methods
  • Pharmacological Effects of Natural Compounds
  • Hormonal Regulation and Hypertension
  • Conservation Techniques and Studies
  • Gastrointestinal Bleeding Diagnosis and Treatment
  • Atrial Fibrillation Management and Outcomes
  • Adrenal Hormones and Disorders
  • Cancer Diagnosis and Treatment
  • Plant-based Medicinal Research
  • Plant Genetic and Mutation Studies
  • Curcumin's Biomedical Applications
  • Infectious Encephalopathies and Encephalitis
  • Knee injuries and reconstruction techniques
  • Food Science and Nutritional Studies

Gheorghe Asachi Technical University of Iași
2019-2022

Clinical Emergency Hospital Bucharest
2018

Carol Davila University of Medicine and Pharmacy
2018

Spitalul Clinic de Recuperare
1982

In this work, a green technique for bioactive compounds extraction from different vegetative organs (leaves, flowers, seeds, stem and root) of Datura innoxia, assisted by ultrasound (UAE), was performed using ethanol 1-butanol as solvents. The chemical compositions the extracts quantitative determination alkaloids (scopolamine) were investigated methods: Fourier transform infrared (FTIR) spectroscopy, fluorescence spectrophotometry (FL), ultraviolet-visible (UV-VIS) spectroscopy gas...

10.35812/cellulosechemtechnol.2025.59.09 article EN Cellulose Chemistry and Technology 2025-03-10

Downy thorn-apple Datura innoxia (Solanaceae) is an invasive plant species which can be introduced either accidentally or deliberately and have the ability to acclimatize in new environmental conditions. Scopolamine a natural alkaloid occur several species, including innoxia. Occurrence of all organs crucially important from viewpoint medical use, but also as risk toxicity for humans animals, this paper presents influence alcoholic solvents on separation tropane alkaloids using conventional...

10.3390/f13101555 article EN Forests 2022-09-23

Tropane alkaloids are characteristic secondary metabolites which occurred mainly in Solanaceae plant family. Among them, hyoscine or scopolamine is one of the predominant Datura species, occurring all organs (vegetative and reproductive). Because its medical use toxic properties, a rapid, convenient reliable method essential for quantification content biomass. The aim this study was to elaborate rapid determination from innoxia, using Soxhlet extraction by gas-cromatography with flame...

10.37358/rc.20.7.8230 article EN cc-by Revista de Chimie 2020-08-04

The main family of phytochemical compounds derived from naturally synthesised secondary metabolites are alkaloids, terpenoids and phenolics. Recently, these known also as novel chemical entities (NCE) have been used drug precursors or templates for synthetic moieties. Also, their potential pharmacological applications has well extensively investigated. However, in recent years, a serious problem worldwide become the use illegal drugs, where to some act bio- psychoactive component is often...

10.2139/ssrn.3388066 article EN SSRN Electronic Journal 2019-01-01

Art is a specific human activity that aims at producing aesthetic values and using means of expression. Moreover, arts are distinguished by the material used (painting - color, sculpture – stone or wood, literature words, music sound note), but they share artistic image underlying act creation. Authentic False in artworks should not only focus on substrate, paints, background, lacquer, also technique to verify it corresponds painter. The resolution these problems cannot be conceived without...

10.2139/ssrn.3434139 article EN SSRN Electronic Journal 2019-01-01

In this study it is presented the application of spectroscopic methods, such as fluorescence and attenuated total reflection Fourier transform infrared analysis for identification detection secondary metabolite specially, hyoscine, organic functional groups from dry biomass Datura innoxia vegetative organs. The experimental results confirmed presence some important classes metabolites useful in medicine domain, e.g., alkaloids, terpenes, phenolics, sterols, carbohydrates. Regarding study,...

10.5802/crchim.169 article EN cc-by Comptes Rendus Chimie 2022-05-03

The present work highlights the results of optical and electronic microscopy analyses performed on fifteen selected outdated 20th century Romanian coins. obtained brought significant contributions in establishing specific archaeometric characteristics corrosion coins products generated within in-use demonetization periods, under action both natural anthropogenic factors. was mainly aimed identifying nature alloy raw material used during minting, with emphasize their resistance toward various...

10.37358/rc.17.9.5846 article EN Revista de Chimie 2017-10-15

Abstract Introduction. The osteosarcoma represents the most frequently encountered primitive malignant bone tumor, representing 30% of tumors with an unpredictable evolution. Materials and methods. A retrospective study realized over a period 3 years (Jan. 2016-Jan. 2018), which included 6 patients diagnosed treated through reconstruction tumor prosthesis technique in Orthopaedics Traumatology Clinic University Emergency Hospital Bucharest. Results. Of total patients, 5 were male 1 was...

10.2478/rojost-2018-0028 article EN Romanian Journal of Orthopaedic Surgery and Traumatology 2018-05-22

The potential of forensic expertise in the analysis soil samples has been recognized for a century now, but over last 20 years, these types evidence have much more widely used both as an investigative tool and court. Forensic Chemistry is at crossroads science with law, being discipline apart from its applicability to judiciary. Samples are obtained various objects often contain only very small amounts chemicals. Most time, sample harvested on spot no longer sampled, it actually be analyzed....

10.2139/ssrn.3459624 article EN SSRN Electronic Journal 2019-01-01
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