A5010630186- Epilepsy research and treatment
- Advanced MRI Techniques and Applications
- Ultrasound and Hyperthermia Applications
- Advanced Neural Network Applications
- Medical Image Segmentation Techniques
- Vascular Malformations Diagnosis and Treatment
- RNA modifications and cancer
- Bacterial Infections and Vaccines
- Cerebrospinal fluid and hydrocephalus
- Metabolism and Genetic Disorders
- Alcohol Consumption and Health Effects
- Tumors and Oncological Cases
- Intracerebral and Subarachnoid Hemorrhage Research
- Congenital Heart Disease Studies
- Vascular Malformations and Hemangiomas
- Autoimmune Neurological Disorders and Treatments
- Neurofibromatosis and Schwannoma Cases
- Glycogen Storage Diseases and Myoclonus
- Brain Tumor Detection and Classification
- Pituitary Gland Disorders and Treatments
- Multiple Sclerosis Research Studies
- Meningioma and schwannoma management
- Congenital Ear and Nasal Anomalies
- RNA regulation and disease
- Teratomas and Epidermoid Cysts
Sree Chitra Thirunal Institute for Medical Sciences and Technology
2018-2025
Medicover
2021
Institute of Medical Sciences
2018-2019
In this work, we have focused on the segmentation of Focal Cortical Dysplasia (FCD) regions from MRI images. FCD is a congenital malformation brain development that considered as most common causative intractable epilepsy in adults and children. To our knowledge, latest work concerning automatic was proposed using fully convolutional neural network (FCN) model based UNet. While there no doubt outperformed conventional image processing techniques by considerable margin, it suffers several...
Background The role of imaging in autoimmune encephalitis (AIE) remains unclear, and there are limited data on the utility magnetic resonance (MRI) to diagnose, treat, or prognosticate AIE. Purpose To evaluate whether MRI is a diagnostic prognostic marker for AIE assess its efficacy distinguishing between various subtypes. Material Methods We analyzed from 96 patients our prospective registry. sequences examined were FLAIR, diffusion, SWI, T2WI, ASL, contrast enhancement. Short-term outcomes...
Central nervous system (CNS) involvement in Sjogren's syndrome (SS) has a broad spectrum of presentations. We present 33-year-old with sudden onset, rapidly progressive quadriplegia, severe dysarthria, bilateral facial palsy, bulbar and hypernatremia. The MRI the brain revealed hyperintensity central pons diffusion-weighted imaging, T2-weighted fluid-attenuated inversion recovery (FLAIR) without abnormal contrast enhancement, consistent pontine myelinolysis. However, there was no antecedent...
A 16-year-old boy, born of nonconsanguineous parentage, had an uneventful birth history and mild global developmental delay. He progressive gait disturbances since 2 years age. Examination revealed generalized dystonia, scanning speech, pendular nystagmus, cerebellar ataxia, spasticity. MRI brain showed features hypomyelination with atrophy the basal ganglia cerebellum (H-ABC) (figure).
A 10-month-old boy, born of nonconsanguineous parents, without any perinatal insult, presented with tonic spasms from the 13th day life. He started having seizures 4 months age, global developmental delay. On examination, there were no neurocutaneous markers, facial dysmorphism, or focal neurologic deficits. EEG (figure) showed generalized and multifocal epileptiform discharges along burst-suppression pattern. MRI brain revealed left perisylvian polymicrogyria (figure).
A 9-year-old girl presented to us with insidious onset difficulty in walking, recurrent falls, anxiety, and poor scholastic performance from age 5 years. Her MRI findings (figure) were classic of L-2-hydroxyglutaric aciduria (L2-HGA). However, similar are also seen Leigh syndrome, 3-hydroxy-3-methylglutaric aciduria, succinic semialdehyde dehydrogenase deficiency. Urine analysis showed elevated levels acid, which confirmed the diagnosis. L2-HGA is a rare autosomal recessive metabolic...
A 10-month-old boy, born of nonconsanguineous parents, without any perinatal insult, presented with tonic spasms from the 13th day life. He started having seizures 4 months age, global developmental delay. On examination, there were no neurocutaneous markers, facial dysmorphism, or focal neurologic deficits. EEG (figure) showed generalized and multifocal epileptiform discharges along burst-suppression pattern. MRI brain revealed left perisylvian polymicrogyria (figure).