- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Infective Endocarditis Diagnosis and Management
- Cardiac Imaging and Diagnostics
- Cardiovascular Health and Disease Prevention
- Atrial Fibrillation Management and Outcomes
- Coronary Artery Anomalies
- Cardiac Structural Anomalies and Repair
- Cardiac tumors and thrombi
- Pulmonary Hypertension Research and Treatments
- Aortic Disease and Treatment Approaches
- Celiac Disease Research and Management
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular Disease and Adiposity
- Congenital Heart Disease Studies
- Cardiac electrophysiology and arrhythmias
- Cardiomyopathy and Myosin Studies
- Sarcoma Diagnosis and Treatment
- Coronary Interventions and Diagnostics
- Cerebrovascular and Carotid Artery Diseases
- Diabetes and associated disorders
- Lymphoma Diagnosis and Treatment
- Infectious Aortic and Vascular Conditions
- Lung Cancer Diagnosis and Treatment
- Acute Ischemic Stroke Management
Sağlık Bilimleri Üniversitesi
2019-2024
Izmir University
2019-2024
University of Health Science
2024
Education and Research Institute
2023
University of Indonesia
2023
Directorate of Health
2023
Izmir Tepecik Eğitim ve Araştırma Hastanesi
2020-2021
Yenişehir Hospital
2021
Ankara Atatürk Eğitim ve Araştırma Hastanesi
2012-2017
Ankara Yıldırım Beyazıt University
2013-2015
Endothelial dysfunction plays an important role in the development of diabetic retinopathy. The aim this study was to evaluate endothelial using different approaches patients with type 1 diabete mellitus early stages For purpose, we investigated serum levels cellular adhesion molecules, including intercellular molecule (ICAM-1), vascular cell (VCAM-1) and endothelin-1 (ET-1), which have emerged as specific markers dysfunction, measured flow-mediated dilatation (FMD), a noninvasive technique...
Background and Objectives:In this study, we examined the role of inflammatory parameters in an apical mural thrombus with a reduced ejection fraction due to large anterior myocardial infarction (MI).Subjects Methods: A total 103 patients who had suffered from heart failure, 45 whom left ventricular (AT) after MI, were enrolled study.A detailed clinical history was taken each participant, biochemical markers, which obtained during admission, analyzed echocardiographical angiographical...
Aim: Celiac disease is characterized by malabsorption resulting from inflammatory injury to the mucosa of small intestine after ingestion wheat gluten or related rye and barley proteins. This study aimed identify individuals who are at risk heart failure increased for cardiovascular events evaluating endothelial function in patients with celiac disease. Materials Methods: The included 36 35 healthy volunteers. After all routine laboratory examination, left ventricular functions were...
In recent years, emerging transcatheter aortic valve implantation (TAVI) has become an alternative for surgery. However, with advanced age, several co-morbid factors together contrast agent usage can cause deterioration in renal function and increase the risk of acute kidney injury (AKI) poor prognosis patients AKI. Therefore, many cannot benefit from this treatment. study, we aim to examine effects TAVI on functions.Seventy patients, mean age 77.6 underwent between July 2011 December 2012....
Objectives: The aim of this single-center study was to assess the incidence and predictors in-hospital access site complications related transcatheter aortic valve implantation (TAVI) performed with new delivery systems in our hospital which has largest case series Turkey. Materials method: We successful TAVI Edwards Sapien XT 127 (46 male) patients via a transfemoral (121), trans-subclavian (5) transapical (1) approach. Access were defined according Valve Academic Research Consortium (VARC)...
Carotid artery diseases are diagnosed more frequently in practice due to increased mean life expectancy of the general population and availability imaging methods. Strong evidence coming from long term, randomized, large studies is required support idea that a carotid stent (CAS) may be an alternative endarterectomy (CEA), which has been performed for years with proven efficacy. Generally, no intervention (CEA or CAS) stenosis external (ECA) literature. In our case, we ipsilateral ECA...
Epicardial adipose tissue (EAT) is a new independent marker of coronary artery disease (CAD). The aim this study was to investigate the relationship between epicardial fat thickness (EFT) and endothelial dysfunction (ED) in patients with type I diabetes mellitus (TIDM).Seventy-six diabetic (diabetes duration 11.7 ± 8,1 years, aged 30.6 10 years; female/male: 38/38) 36 healthy controls were enrolled into study. Fasting plasma glucose (FPG), lipid panel, glycosylated hemoglobin (HbA1C),...
Recent studies have reported an increased incidence of both aortic stiffness and left ventricular (LV) systolic diastolic dysfunction in patients with inflammatory bowel disease (IBD). However, the association between LV function has not been fully defined. We aimed to investigate relationship IBD patients.Seventy-two (56 cases ulcerative colitis 16 Crohn's disease) 50 healthy controls were consecutively enrolled this study. The functions assessed using conventional echocardiographic...
We aimed to investigate the association between aortic function (aortic stiffness index, strain, and distensibility), which is a predictor of atherosclerosis, coeliac disease (CD).Thirty-six patients with CD 35 control subjects were included in study. Serological screening was performed determine levels auto-immune markers, including anti-gliadin immunoglobulin (Ig)A IgG, anti-tissue transglutaminase antibodies. Aortic distensibility, index calculated using echocardiography.Aortic strain...
Transient contrast neurotoxicity is a rare but well-recognized complication of angiography that due to the agent. Patients with renal dysfunction may be inclined develop medium delayed elimination in metabolism. In this report, we present an unusual case transient patient severe chronic kidney disease following percutaneous coronary intervention mimicking clinically and radiologically subarachnoid hemorrhage. The patient's clinical symptoms improved rapidly fully recovered after hemodialysis...
Rivaroxaban, a highly selective direct factor Xa inhibitor, is new oral anticoagulant approved by the US Food and Drug Administration in November 2011 for stroke prophylaxis patients with nonvalvular atrial fibrillation. Because of its efficacy once-a-day dosing, it commonly preferred fibrillation intolerance to warfarin clinical practice. However, can result some adverse effects such as bleeding, rashes liver injury. Here, we described very rare reaction rivaroxaban, jaundice due...
In our study, we aimed to evaluate left ventricular function in patients with Sjögren syndrome (SS) using tissue Doppler echocardiography (TDE) and myocardial performance index (MPI) addition conventional echocardiographic methods.We evaluated 50 SS 48 healthy volunteers similar demographic characteristics. Systolic diastolic functions of the ventricle were analyzed standard two-dimensional (2D) echocardiography, M-mode pulsed-wave (PW) imaging.Septal part mitral annulus PW TDE showed that...
Capable of multi-organ involvement in Sjogren's syndrome (SS), cardiac findings pulmonary effusion, left ventricular diastolic dysfunction and hypertension are seen patients with SS. Aortic stiffness (AS) reflects the mechanical tension elasticity aorta. In this study, our aim is to determine if there any differences AS function between diagnosed as SS healthy control groups.We enrolled 50 47 volunteers similar demographic characteristics. It was found that isovolumetric relaxation time...
Transcatheter aortic valve implantation (TAVI) was introduced as an alternative treatment for patients with severe symptomatic stenosis whom surgery would be high-risk. Prosthetic endocarditis is a serious complication of surgical AVR (SAVR) high morbidity and mortality. According to recent cases, post-TAVI prosthetic (PVE) seems occur very rarely. We present the case 75-year-old woman who underwent TAVI (Edwards Saphien XT) uneventful postoperative stay. She diagnosed using three...
Chronic increased afterload due to severe aortic stenosis (AS) results in com-pensatory concentric left ventricular (LV) hypertrophy and LV dysfunction. These turn cause remodeling of the heart. The aim this study was investigate acute effect transcatheter valve implantation (TAVI) on atrial (LA) mechanics diastolic function.The consisted a total 35 consecutive patients (mean age 77.7 ± 5.0 years, 25 female) undergoing TAVI. All TAVI procedures have been performed under transesophageal...
Abstract Purpose The syndromes of myocardial infarction/myocardial ischemia with No Obstructive Coronary Artery Disease (MINOCA/INOCA) are seen more and often. Endothelial dysfunction (ED) leading to ischemic events has been reported in many these patients. We aimed compare patients MINOCA INOCA regarding brachial artery flow‐mediated endothelium‐dependent vasodilation (flow‐mediated dilation [FMD]) plasma concentration cardiotrophin‐1 (CT‐1). Methods included 42 38 INOCA. function was...
Background and Aim Pulmonary hypertension ( PH ) is common in patients with severe aortic stenosis AS ). The prognostic effect of high‐risk undergoing transcatheter valve implantation TAVI remains unknown. aim this study was to examine the feasibility determine on . Methods Results performed 70 (mean age, 77.6 years; 51 females 19 males) between July 2011 December 2012, our hospital. were divided into three groups based their systolic pulmonary artery pressure sPAP values. Group 1 comprised...
Transcatheter aortic valve replacement can be an effective, reliable treatment for severe stenosis in surgically high-risk or ineligible patients. However, various sequelae like coronary artery obstruction occur, not only the long term, but also immediately after procedure. We present case of a 78-year-old woman whose left main became obstructed with calculus 2 hours transfemoral implantation Edwards Sapien XT valve. Despite percutaneous intervention that artery, patient died. This reminds...
Celiac is predominantly a disease of the small intestine characterized by chronic malabsorption in genetically susceptible individuals who ingest grains containing gluten, such as wheat, barley, and rye. In present study, we evaluate left ventricular function patients with celiac using strain rate echocardiography imaging. Materials methods: Twenty 20 healthy controls were included this study. Left ventricle systolic diastolic functions evaluated standard 2-dimension, M-mode, conventional...
Aortic stenosis (AS) induces pressure overload of the left ventricle (LV) and results in ventricular hypertrophy. The remodeling LV patients with AS is a com-plex process including structural functional disturbances. After aortic valve replacement, reverse begins. aim this study was to evaluate impact transcatheter ımplantation (TAVI) on mass (LVM) early mid-term follow-ups after procedure.We enrolled consecutive 75 who underwent successful TAVI. Transthoracic echocardiography performed...
It has been demonstrated that right ventricular systolic dysfunction develops soon after surgical aortic valve replacement (s-AVR). While the impact of s-AVR or TAVI on function left ventricle studied with various imaging modalities, little is known about (RVF). In current study, we evaluated RVF using conventional echocardiography parameters.Echocardiography was performed prior to 24 h, 1 month and 6 months TAVI. assessed (1) tricuspid annular plane excursion (TAPSE); (2) RV Tissue Doppler...
Transcatheter aortic valve implantation for severe symptomatic stenosis in patients with a previous mitral prosthesis is technically challenging, and pre-procedural comprehensive assessment of these before transcatheter vital an uncomplicated successful procedure.We want to share our experience preexisting functional describe series important technical details.At center, 135 were treated implantation. Six them received Edwards SAPIEN XT through the transfemoral route.Transcatheter was...