A5075544878- COVID-19 Clinical Research Studies
- Folate and B Vitamins Research
- Clinical Laboratory Practices and Quality Control
- Lipid metabolism and disorders
- Liver Disease Diagnosis and Treatment
- Vitamin D Research Studies
- Apelin-related biomedical research
- Adipokines, Inflammation, and Metabolic Diseases
- Gestational Diabetes Research and Management
- Heart Failure Treatment and Management
- Hemoglobinopathies and Related Disorders
- Adipose Tissue and Metabolism
- Cardiovascular Function and Risk Factors
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Spondyloarthritis Studies and Treatments
- Inflammasome and immune disorders
- Sepsis Diagnosis and Treatment
- Cardiovascular Health and Disease Prevention
- Hormonal Regulation and Hypertension
- Vitamin C and Antioxidants Research
- Trace Elements in Health
- Growth Hormone and Insulin-like Growth Factors
- Pituitary Gland Disorders and Treatments
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Diabetes, Cardiovascular Risks, and Lipoproteins
Sağlık Bilimleri Üniversitesi
2017-2025
Izmir Tepecik Eğitim ve Araştırma Hastanesi
2015-2024
Yenişehir Hospital
2019-2024
Izmir University
2017-2023
University of Health Science
2023
Gazi University
2022
Altınbaş University
2022
Ege University
2022
Ministry of Health
2012-2021
Creative Commons
2019
Summary Halicioglu O, Aksit S, Koc F, Akman SA, Albudak E, Yaprak I, Coker Colak A, Ozturk C, Gulec ES. Vitamin D deficiency in pregnant women and their neonates spring time western Turkey. Paediatric Perinatal Epidemiology 2012; 26: 53–60. Although Turkey is located a sunny region, vitamin still serious health problem infants, especially among the low socio‐economic status Turkish population. This study was carried out order to measure serum 25‐hydroxyvitamin D3 [25(OH)D] concentrations of...
Ankylosing spondylitis (AS) is a chronic inflammatory disease of spine and sacroiliac joints; it characterized by new bone formation, the processes can be accompanied osteoporosis. In present study, we investigated changes in mineral density (BMD) levels various turnover-related biomarkers cytokines cohort AS patients, with regard to clinical parameters, activity, treatment regimen.55 patients 33 healthy controls included study. Spinal mobility was assessed Bath Spondylitis Metrology Index...
Abstract Objectives Oxidative stress occurs when free radicals accumulate at high levels in the body, affecting biological molecules. Some studies have focused on multisystemic involvement, signs of premature aging, and potential role oxidative pathogenesis myotonic dystrophy type 1 (DM1). We aimed to evaluate markers patients diagnosed with DM1. Methods In a cross-sectional study, 27 clinically genetically confirmed DM1 34 healthy individuals matched for age gender were included. markers,...
Introduction: Studies about vitamin D [25(OH)D] stability in plasma are limited and preanalytical variables such as tube type may affect results. We aimed to evaluate effect of storage conditions, sample some on concentration.
Serum procalcitonin (PCT) and C-reactive protein (CRP) are markers of systemic inflammation bacterial infection. We aimed to compare the usefulness CRP in patients with community-acquired pneumonia exacerbations chronic obstructive pulmonary disease (COPD).A total 116 consecutive were included study: 76 group 1, 40 2.Median serum level was 44 mg/L COPD 132 group. Median value PCT found be 0.07 0.14 ng/mL levels significantly higher compared (p<0.001). The area under ROC curve 0.788 (CI:...
Objectives The aim of this study was to investigate the effect carbamazepine (CBZ) and sodium valproate (VPA) monotherapy on sexual functions, sex hormones, semen analysis quality in male patients with epilepsy. Methods A total 59 epilepsy, which 30 were VPA 29 CBZ monotherapy, included between January 2015 March 2016. control group established healthy males. Luteinizing hormone (LH), follicle-stimulating (FSH), prolactin (PRL), free testosterone (fT), estradiol (E2), hormone-binding...
Objective: To investigate the frequencies of vitamin B12 and folate deficiencies in pregnant women low socioeconomic group, relation between animal-source foods consumption maternal B12-folate statuses, their impacts on anthropometric measurements infants. Methods: A total 208 last trimester were included study. questionnaire about socio-demographic status, meat, egg, milk-dairy products, multivitamin supplementation was used. Vitamin concentrations studied by chemiluminescence method. The...
Irisin, a recently identified myokine, is associated with increased energy expenditure and has potential role in obesity. Therefore, we investigated circulating irisin levels morbidly obese patients undergoing sleeve gastrectomy (SG).Thirty SG 30 healthy subjects were included. All participants evaluated at baseline again three months post-SG. Body weight height, the lipid profile, plasma glucose, HbA1c, insulin, measured each visit.The two groups had similar mean age sex distribution. Serum...
In this present study, we aimed: (i) To clarify if prediabetes is associated with subclinical inflammation independent of underlying obesity, and (ii) to evaluate the effect postload glucose concentration on markers in a group patients elevated fasting glucose.In cohort 165 newly detected hyperglycemia, according 75 g oral tolerance test (OGTT), subjects were classified either as diagnosed type 2 diabetes (diabetes group, n = 40), impaired (IFG) plus (IGT) (IFG/IGT 42) or IFG only (IFG 83)....
In this study, our aim was to determine the differences between intrauterine growth restriction (IUGR) and normal birth weight fetuses in terms of ischemia modified albumin (IMA) levels. For purpose, we measured levels cord blood venous mothers.This study is a prospective conducted at University Health Sciences Tepecik Training Research Hospital January 2018 December 2019. According inclusion/exclusion criteria, 227 patients were included study. Participants divided into two groups according...
Summary Introduction Anemia and macrocytosis are well‐defined expected hematologic findings of vitamin B 12 folate deficiency; however, some previous studies did not show a significant association subnormal with anemia macrocytosis. Methods We retrospectively analyzed 17 713 laboratory patient records to evaluate levels in relation Results In an age‐ sex‐adjusted logistic regression model, low status but marginal was significantly associated [ OR s respectively, 1.291 (95% CI , 1.182–1.410),...
Objective: Although vitamin D deficiency have been suggested in children is widespread recently, the data about status of Turkish limited.The objective present study was to determine prevalence Aegean region and show effect age, gender seasons on levels.The from hospital information system examined retrospectively.Method: Between January 2011 February 2013, admitted department paediatrics our for health examination taken blood measurement.Serum levels were determined by...
In this study, we aimed to evaluate serum irisin and apelin levels in patients with subclinical hypothyroidism (SCH) when they were hypothyroid become euthyroid after levothyroxine therapy association of these adipokines markers atherosclerosis such as homocysteine carotid intima-media thickness (IMT).The study included 160 newly diagnosed due Hashimoto's thyroiditis 86 healty subjects. Serum glucose lipid profile, insulin, HOMA, TSH, free T3, T4, anti-thyroperoxidase anti-thyroglobulin...
Abstract Centrifugation separates particles within the specimen according to their shape, dimensions, and density basically can be defined as a separation method. The centrifuge is an essential device in medical laboratories prepare serum, plasma, urine samples for analysis. It electric composed of stationary (motor) motile (rotor) part. centrifugation depends on two main variables: relative centrifugal force (RCF) time. physical impact separating into its components known RCF expressed...
Familial Mediterranean fever (FMF) is an auto-inflammatory disease characterised by periodic inflammatory attacks. We investigated changes in monocyte-granulocyte derived S10012A and chitotriosidase both the attack silent period of FMF for better estimation inflammation. Endogenous resolvin was determined utility to restrict This study included 29 patients (15 M/14 F) 30 healthy controls M/15 F). Serum levels highly sensitive C-reactive protein, serum amiloid A (SAA), S100A12,...
Diabetic nephropathy (DN) is the major cause of chronic renal failure, and proteinuria an independent risk factor for end stage disease. The random urine protein: creatinine ratio (P:C ratio) can accurately predict amount 24-hour urinary protein excretion. Apelin thought to be associated with endothelial dysfunction, angiogenesis, inflammation. This study investigated apelin concentration its association P:C ratio, metabolic parameters in subjects without type 2 diabetes mellitus (T2D).This...
Background As plasma is the recommended sample type for Roche adrenocorticotropic hormone (ACTH) assay, we evaluated effect of EDTA concentration on Cobas ACTH assay. Methods Samples containing twofold and fourfold higher concentrations were prepared by adding to empty K2EDTA tubes making under-filled tubes. All measurements performed with four replicates. Results Increased resulted in a significant decrease concentration. Fifty-per cent-filled tube showed 19% 25% filled 50% Conclusion We...
To determine the clinical significance of serum 25-hydroxy (OH) vitamin D levels in pediatric patients with multisystem inflammatory syndrome children (MIS-C) and compare these those Coronavirus disease-2019 (COVID-19) healthy controls.This study was designed for aged 1 month to 18 years conducted between July 14 December 25, 2021. Fifty-one MIS-C, 57 who were hospitalized COVID-19, 60 controls enrolled study. Vitamin insufficiency defined as a 25 level less than 20 ng/mL. Severe MIS-C...
Introduction: We aimed to evaluate 304 premenopausal women admitted our clinic for oligomenorrhoea, and screen Cushing's syndrome (CS) in this population. Material methods: The study included referred oligomenorrhoea. Anthropometric measurements Ferriman-Gallwey score were evaluated, thyroid hormone, follicle-stimulating hormone (FSH), luteinizing (LH), total testosterone, prolactin, dehydroepiandrosterone sulphate (DHEA-S), 17-hydroxyprogesterone (17-OHP) levels measured all patients. If...
Abstract Objectives Artificial intelligence–based robotic systems are increasingly used in medical laboratories. This study aimed to test the performance of KANKA (Labenko), a stand-alone, artificial robot that performs sorting and preanalytical quality control blood tubes. Methods is designed perform with respect error To detect errors inappropriateness within routine work laboratory, total 1000 tubes were presented 7 scenarios. These scenarios encompassed various days runs, 5 repetitions...