A5067165486- Clinical Laboratory Practices and Quality Control
- COVID-19 Clinical Research Studies
- Venous Thromboembolism Diagnosis and Management
- Vitamin D Research Studies
- Folate and B Vitamins Research
- Meta-analysis and systematic reviews
- Diet and metabolism studies
- Pediatric Urology and Nephrology Studies
- Esophageal and GI Pathology
- Blood transfusion and management
- Potassium and Related Disorders
- Blood properties and coagulation
- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Pancreatitis Pathology and Treatment
- Paraoxonase enzyme and polymorphisms
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Adipokines, Inflammation, and Metabolic Diseases
- Humic Substances and Bio-Organic Studies
- Thyroid Disorders and Treatments
- Hemophilia Treatment and Research
- Musculoskeletal pain and rehabilitation
- Regulation of Appetite and Obesity
- Chemotherapy-induced organ toxicity mitigation
- Traumatic Brain Injury and Neurovascular Disturbances
Bakırçay Üniversitesi
2023-2025
Izmir University
2017-2025
Sağlık Bilimleri Üniversitesi
2017-2023
Izmir Tepecik Eğitim ve Araştırma Hastanesi
2015-2021
Dokuz Eylül University
2021
Tokat Gaziosmanpaşa Üniversitesi
2020
Yenişehir Hospital
2017-2018
Education Training And Research
2014-2018
University of Health Sciences
2017
University of Health Science
2017
Urinalysis is one of the most commonly performed tests in clinical laboratory. However, manual microscopic sediment examination labor-intensive, time-consuming, and lacks standardization high-volume laboratories. In this study, concordance analyses between two different automatic urine analyzers has been evaluated.
To investigate the effects of all-trans retinoic acid (ATRA) in cisplatin (CP)-induced testicular damage rats.Twenty-eight male Wistar rats were divided into four groups: Control, ATRA alone, ATRA+CP, and CP alone. Body weight, sperm count, motility, percentage abnormal sperm, total antioxidant status (TAS), oxidant (TOS), oxidative stress index (OSI) tissue, histopathology compared among groups.The count motility significantly decreased increased group to control groups. CP+ATRA...
Highlights • This study provided updated biological variation (BV) estimates for thyroid hormones in 21 healthy Turkish volunteers Although BV function tests our were found to be different than some previously published, they compatible with European Federation of Clinical Chemistry and Laboratory Medicine meta-analysis data obtained using immunoassay methods populations The analytical performance specifications stimulating hormone higher those free triiodothyronine thyroxine As have low...
Abstract Objectives Oxidative stress occurs when free radicals accumulate at high levels in the body, affecting biological molecules. Some studies have focused on multisystemic involvement, signs of premature aging, and potential role oxidative pathogenesis myotonic dystrophy type 1 (DM1). We aimed to evaluate markers patients diagnosed with DM1. Methods In a cross-sectional study, 27 clinically genetically confirmed DM1 34 healthy individuals matched for age gender were included. markers,...
The most common sources of error in the preanalytical phase are considered to be at stage patient preparation and sample collection. In order reduce errors, we aimed determine level phlebotomists knowledge about preanalytic before after planned trainings study.Training processes was given 454 health professionals majority them were employed as nurse. Questionnaires training conducted. assess effect into process, rates calculated training.The total correct answer vocational school diplomaed...
Although serum-providing blood tubes with a barrier are still widely used due to their significant advantages, the use of provide plasma is becoming widespread. We compared 22 analytes in BD Vacutainer® Barricor LH Plasma tube for local clinical validation this new lithium heparin barrier.Samples from 44 volunteers were collected different (Becton Dickinson and Company): Z without additive (reference), clot-activator gel (SST), (LiH), (Barricor). Analyte concentrations reference tube. All...
Background: The klotho (Klt)-fibroblast growth factor-23 (FGF-23)-vitamin D axis is the main component of calcium (Ca) and phosphorus (P) metabolisms; on contrary, it also secreted from choroid plexus (CP). Purpose: This study aimed at evaluating serum soluble Klt (sKlt), FGF-23, 25-(OH)-vitamin levels in multiple sclerosis (MS) patients. Methods: Thirty-two relapsing-remitting MS patients (11 males 21 females; mean age 38.3 years) 31 age-sex matched healthy controls (12 19 median 38.5 were...
Objectives: Ischemia/reperfusion (I/R) injury is a common cause of renal and to date, many pharmacological agents have been identified decrease I/R injury. One the potential compound that can target chlorogenic acid (CGA). It has potent antiinflammatory, antibacterial, anti-oxidant, analgesic antipyretic activities in vitro experiments vivo animal models. The aim study was investigate protective characteristic CGA on Material Methods: 24 rats were randomly allocated three groups (n = 8):...
Traumatic spinal cord injury (TSCI) is an important health problem, especially in developing countries withadditional socioeconomic loss. Humic acid (HA) usually has antioxidant, antiinflammatory, blood circulating, and antiviral effects.Hence, it was aimed herein to show the effect of HA on neuroprotection a TSCI model.Materials method: A model used, which 24 Wistar albino rats were divided into 4 groups: control group: subjectedto only laminectomy; sham subjected laminectomy + TSCI; 5...
Aim We aimed to investigate the significance of faecal calprotectin (FC) levels in children diagnosed with Henoch–Schönlein purpura (HSP) and examine its relationships gastrointestinal system (GIS), renal involvement clinical findings. Patients methods In total, 66 HSP for first time a control group 25 healthy were included. The cases divided into mild severe groups on basis GIS FC was measured twice all patients HSP: within 3 days onset disease (FC1) day 15 (FC2). These results compared...
Introduction: The blood collection for laboratory tests has been frequently performed due to evidence-based medicine. We aimed conduct a survey on phlebotomy among phlebotomists and patients reduce unnecessary loss by using small-volume tubes.
 Materials Methods: A was conducted gather their opinions. Phlebotomists received training the importance of preanalytical process. volume required reduced 33.3%-50.0% in children adults, 63.0%-84.0% newborns. Following this intervention, we...
To interpret test results correctly, understanding of the variations that affect is essential. The aim this study is: 1) to evaluate clinicians' knowledge and opinion concerning biological variation (BV), 2) investigate if clinicians use BV in interpretation results.This uses a questionnaire comprising open-ended close-ended questions. Questions were selected from real-life numerical examples results, about main sources laboratories on BV. A total 399 interviewed, answers evaluated using...
To explore the possible contribution of apolipoprotein (apo) E polymorphisms to extent and severity coronary artery disease (CAD) related lipid metabolism.Overall, 53 Turkish patients, aged 54+/-11 years defined by angiography were included in this cross-sectional study. Reardon's scoring was used. Serum lipids measured with enzymatic colorimetric methods. Apolipoproteins nephelometry. Apolipoprotein gene determined reverse hybridization method. Statistical analyses performed using one-way...
Background: In order to apply the right treatment for hemostatic disorders in pediatric patients, laboratory data should be interpreted with age-appropriate reference ranges. Objectives: The purpose of this study was determining age-dependent range values prothrombin time (PT), activated partial thromboplastin (aPTT), fibrinogen tests, and D-dimer tests. Materials Methods: A total 320 volunteers were included following ages: 1 month - year (n = 52), 2 5 years 50), 6 10 48), 11 17 38), 18 65...
Coronavirus disease 2019 (COVID-19) in children is milder than adults. Household virus exposure may affect clinical severity. We aimed to determine the household contact history of patients and its influence on stage.One hundred seventy-three pediatric with COVID-19 as diagnosed positive real-time polymerase chain reaction for severe acute respiratory syndrome coronavirus-2 aged 1 month 18 years were included. Demographic data, laboratory findings, obtained. They classified according their...
Biological variation is defined as the in analytical concentration between and within individuals, being aware of this biological important for understanding disease dynamics. The aim our study to calculate within-subject (CVI) between-subject (CVG) variations serum creatinine, cystatin C beta trace protein (BTP), well reference change value (RCV) individuality indexes (II), which are used glomerular filtration rate while evaluating kidney damage.Blood samples were collected from 22 healthy...