A5078569260- Clinical Laboratory Practices and Quality Control
- Liver Disease Diagnosis and Treatment
- Meta-analysis and systematic reviews
- Vitamin D Research Studies
- Thyroid Disorders and Treatments
- Advanced Glycation End Products research
- Ocular Surface and Contact Lens
- Diet, Metabolism, and Disease
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Pituitary Gland Disorders and Treatments
- Glaucoma and retinal disorders
- Pharmacological Effects and Toxicity Studies
- Human Health and Disease
- Cardiovascular Disease and Adiposity
- Sulfur Compounds in Biology
- Diabetes Management and Research
- Obstructive Sleep Apnea Research
- Biosimilars and Bioanalytical Methods
- Biochemical effects in animals
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Bone health and treatments
- Drug-Induced Hepatotoxicity and Protection
- melanin and skin pigmentation
- Poisoning and overdose treatments
- Radiopharmaceutical Chemistry and Applications
Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi
2013-2024
Sağlık Bilimleri Üniversitesi
2018-2024
Abbott (Germany)
2022
Roche (Switzerland)
2022
Laboratoire de Biochimie
2018
Karadeniz Technical University
2018
Universidad CES
2018
University of Health Science
2018
Ministry of Health
2013-2018
Bursa Uludağ Üni̇versi̇tesi̇
2018
Red cell distribution width (RDW) is independently associated with morbidity and mortality in cardiovascular diseases. RDW elevated hypertensive patients compared normotensives. Based on the nocturnal course, hypertension classified as dipper non-dipper. Non-dipper higher inflammation worse prognosis. We aimed to investigate whether high-sensitive C-reactive protein (hsCRP) are non-dipper dippers. The study included total 247 essential patients. Twenty-four-hour ambulatory blood pressure...
The aim of this study was to evaluate the potential use serum transforming growth factor-β1 (TGF-β1), tissue inhibitor metalloproteinase-1 (TIMP-1), fetuin-A, and fibroblast factor 21 (FGF21) in detection liver fibrosis patients with chronic hepatitis B (CHB). value noninvasive models - that is, aspartate aminotransferase platelet ratio index (APRI), based on four factors (FIB-4) score, Forn's also examined.CHB who underwent biopsy for evaluation were included study. A total 73 divided into...
<b><i>Purpose:</i></b> To compare tear film osmolarity (TFO) between patients with diabetes mellitus (DM) and normal healthy individuals. <b><i>Methods:</i></b> In this prospective case-controlled study, the TFO in 46 subjects (control group) 55 DM (study was evaluated. milliosmole (mOsm) measured by using an auto-osmometer. The serum levels of glycosylated hemoglobin (HbA<sub>1</sub>c) blood glucose all participants were also...
Introduction: Acetaminophen (APAP) is an analgesic and antipyretic agent. In overdoses, it associated with nephrotoxicity. We examined the potential protective effects of N-acetylcysteine (NAC) NAC + ozone therapy (OT) combination against APAP-induced Materials methods: Thirty-two male Sprague–Dawley rats were divided into four groups: sham, control (APAP), NAC, OT. APAP, OT groups, kidney injury was induced by oral administration 1 g/kg APAP. The group received (100 mg/kg/day). mg/kg/day)...
ubclinical hypothyroidism (SCH) and hypert t thyroidism represent the earliest stages of thyt roid dysfunction. 1 SCH is defined by finding elevated serum thyrotropin (TSH) concentrations associated with normal free thyroid hormone levels a lack clinical signs symptoms hypothyroidt ism.2t4 usually detected during followtup patients history disease or as result biochemical screening for nonspecific symptoms. 5hether has any demonstrable effect on lipid been controversial. 2,3,5t10 Several...
The most important effect of vitamin D is on calcium homeostasis and bone health. 25 hydroxy (25-OH D) level should be measured to evaluate Vitamin levels. aim this study was determine whether deficiency in patients admitted our hospital establish the difference between 25-OH levels according gender age groups. a general adult population 01.12.2010-22.08.2011 were investigated retrospectively through information system. Participants who had chronic illnesses excluded from study. Subjects...
Inflammation plays an important role in acute ischemic stroke. In this study we aimed to investigate the relationship between stroke and serum amyloid A, fetuin-A, pentraxin-3 which are inflammation markers.We enrolled 52 patients with 30 sex-matched control subjects study. The were followed for 3 months. We evaluated common risk factors, laboratory variables, neurological examination of according prognosis scales.The median levels higher than (respectively, P = 0.000, 0.002, 0.037)....
Isotretinoin, the drug of choice for severe acne, might be associated with a decrease in insulin sensitivity. Adiponectin is an adipose tissue-derived protein that increases In this study, we aimed to investigate adiponectin levels postadolescent acne and effect isotretinoin on levels.Participants included 18 female patients healthy women matched age body mass index (BMI). Acne completed 6-month treatment. Anthropometric measurements, serum adiponectin, lipids, fasting glucose, insulin,...
Abstract Objectives The application of Sigma metrics can be used for assessing the performance diagnostic laboratories. Clinical laboratories are confronted with trouble having to select best and suitable quality specifications that required planning. In this regard, our study aims at evaluating Sysmex XN-1000 hematology analyzer by using based on different total allowable error (TEa) source determine effects these variations in metric evaluation. Methods Five TEa requirements were selected...
An overdose of acetaminophen (APAP) produces centrilobular hepatocellular necrosis. We aimed to investigate the hepatoprotective effects N-acetylcysteine (NAC) only and hyperbaric oxygen (O 2 ) treatment (HBOT) combined with NAC, their anti-inflammatory properties in liver tissue. In current study, a total 32 male Sprague Dawley rats were divided into 4 groups: sham, APAP, NAC + HBOT. HBOT groups, injury was induced by oral administration 1 g/kg APAP. The group received 100 mg/kg per day....
Purpose: To determine the serum thiol disulfide homeostasis in patients with pseudoexfoliation (PEX) syndrome.Method: Thirty-five PEX syndrome and forty healthy subjects were included this observational case-control study. Serum native thiol, total disulfide, thiol/disulfide ratio determined using a novel automated assay.Results: The mean levels significantly lower compared to controls (p = 0.001). level was higher 0.023). (16 ± 10.1 vs 22.3 11.5, respectively, p 0.014).Conclusion: Our...
Background Hyperemesis gravidarum, which affects 0.3–2.3% of pregnancies, is defined as excessive vomiting during pregnancy and usually starts in week 4 or 5 gestation. Symptoms include weight loss, dehydration, ketonaemia, ketonuria, fasting acidosis, alkalosis due to hydrochloric acid loss hypokalaemia its exact cause unknown. The present study was undertaken investigate the relationship between prealbumin, ghrelin, nesfatin-1 obestatin concentrations pregnancies associated with...
Sample classification and registration have been recognized as important time-consuming processes in laboratories. There is increasing pressure on laboratories to automate due intense workload reduce manual procedures errors. The aim of the present study was evaluate positive effects an automatic tube sorting system specimen processing.
To interpret test results correctly, understanding of the variations that affect is essential. The aim this study is: 1) to evaluate clinicians' knowledge and opinion concerning biological variation (BV), 2) investigate if clinicians use BV in interpretation results.This uses a questionnaire comprising open-ended close-ended questions. Questions were selected from real-life numerical examples results, about main sources laboratories on BV. A total 399 interviewed, answers evaluated using...