Osman Yüksel

ORCID: 0000-0003-4784-908X
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About
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Research Areas
  • Liver Disease Diagnosis and Treatment
  • Pancreatic and Hepatic Oncology Research
  • Gastric Cancer Management and Outcomes
  • Gallbladder and Bile Duct Disorders
  • Gastrointestinal disorders and treatments
  • Pancreatitis Pathology and Treatment
  • Drug-Induced Hepatotoxicity and Protection
  • Hepatitis C virus research
  • Hepatitis B Virus Studies
  • Esophageal and GI Pathology
  • Helicobacter pylori-related gastroenterology studies
  • Liver Disease and Transplantation
  • Colorectal Cancer Surgical Treatments
  • Pediatric Hepatobiliary Diseases and Treatments
  • Abdominal vascular conditions and treatments
  • Colorectal Cancer Screening and Detection
  • Microscopic Colitis
  • Gastrointestinal motility and disorders
  • Inflammatory Bowel Disease
  • Gastrointestinal Tumor Research and Treatment
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Metabolism and Genetic Disorders
  • Diverticular Disease and Complications
  • Inflammatory Biomarkers in Disease Prognosis
  • Anorectal Disease Treatments and Outcomes

Gazi University
2011-2024

Gazi Hastanesi
2007-2021

Hacettepe University
2013-2019

Massachusetts General Hospital
2016-2017

Harvard University
2017

Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi
2009-2016

Usak University
2016

Society of Gastroenterology Nurses and Associates
2016

Ankara Numune Eğitim ve Araştırma Hastanesi
2005-2013

Türkiye Yüksek İhtisas Hastanesi
2003-2011

Many non-invasive tests have been studied for diagnosis and determining the activation degree of inflammatory bowel disease (IBD). Nevertheless, an ideal test has not found yet. Mean platelet volume (MPV) is influenced by inflammation. In a few study, decreased reported in IBD. The aim this study to determine whether would be useful ulcerative colitis (UC) activity. Additionally we analyzed overall accuracy MPV activity compared with other markers. A total 61 UC patients (male/female :...

10.1080/09537100902856781 article EN Platelets 2009-01-01

To assess the prevalence of concurrent extrahepatic autoimmune diseases in patients with hepatitis (AIH)/primary biliary cirrhosis (PBC) overlap syndrome and applicability 'mosaic autoimmunity' these patients.The medical data 71 AIH/PBC were evaluated for associated diseases.In study population, 31 (43.6%) had diseases, including thyroid (13 patients, 18.3%), Sjögren (six 8.4%), celiac disease (three 4.2%), psoriasis rheumatoid arthritis vitiligo (two 2.8%), systemic lupus erythematosus...

10.1097/meg.0b013e328350f95b article EN European Journal of Gastroenterology & Hepatology 2012-01-26

Gastric cancer is the fourth most frequent and second cause of cancer-related deaths worldwide. The early diagnosis gastric fundamental in decreasing mortality rates. It has been shown that MPV level a sign inflammation hepatocellular carcinoma pancreatic adenocarcinoma. aim this study to examine whether would be useful inflammatory marker for differentiating patients from healthy controls. Thirty-one 31 age-sexes matched subjects included into study. Patients with hypertension,...

10.3109/09537104.2013.783689 article EN Platelets 2013-03-28

The aim of this study was to evaluate the potential use serum transforming growth factor-β1 (TGF-β1), tissue inhibitor metalloproteinase-1 (TIMP-1), fetuin-A, and fibroblast factor 21 (FGF21) in detection liver fibrosis patients with chronic hepatitis B (CHB). value noninvasive models - that is, aspartate aminotransferase platelet ratio index (APRI), based on four factors (FIB-4) score, Forn's also examined.CHB who underwent biopsy for evaluation were included study. A total 73 divided into...

10.1097/meg.0b013e32835fd699 article EN European Journal of Gastroenterology & Hepatology 2013-03-22

Introduction: Many noninvasive tests have been studied for the diagnosis and determining liver fibrosis score (LFS).In this study, we aimed to research correlation of mean platelet volume (MPV) stage in patients with chronic hepatitis B (CHB).Patients Methods: Fifty-nine CHB were enrolled retrospectively into study.Age-sex matched 25 healthy subjects used as control group.The following data obtained from computerized patient registry database: HBV-DNA level, e-antigen seropositivity, enzymes...

10.1002/jcla.20450 article EN Journal of Clinical Laboratory Analysis 2011-01-01

Emergency cholecystectomy for acute cholecystitis is associated with high morbidity and mortality rates in patients significant comorbidities high-risk surgery. The aim of this study was to evaluate the effectiveness, possible advantages, complications percutaneous cholecystostomy (PC) followed by an early laparoscopic (LC) relation conservative treatment a delayed LC high-surgical risk patients. Between 2002 2004, were randomly classified into 2 groups: first group consisted who had PC...

10.1097/01.sle.0000191619.02145.c0 article EN Surgical Laparoscopy Endoscopy & Percutaneous Techniques 2005-12-01

We regret to inform you that the criticism raised by Editorial Board is correct concerning similarity between some parts of texts present in our article published Digestion [2011;83:83–88], and papers Journal Hepatology [2005;43:1007–1012] [2009;49:1421–1423], although research data are completely independent. apologize for this unfortunate error, which was established during writing process manuscript author Harun Erdal. Although final version submitted paper had been examined all authors,...

10.1159/000320379 article EN Digestion 2010-10-30

Abstract Background Antibodies to soluble liver antigen (anti‐ SLA ) are specific serological markers of autoimmune hepatitis ( AIH ). The clinical significance and frequency anti‐ have never been reported among patients from Italy Turkey. To retrospectively assess the estimated prevalence, sensitivity, specificity in various diseases. Methods A total 986 who had tested for serum were included study. presence was detected using recombinant enzyme linked immunosorbent assay immuno‐blot....

10.1111/liv.12022 article EN Liver International 2012-10-17

Celiac disease (CD) is an autoimmune that develops in patients with a genetic predisposition, incurring susceptibility to gluten-containing foods such as barley, wheat, and rye. The elimination of gluten from the diet main therapeutic approach usually leads clinical laboratory improvement. There are no ideal markers objectively assess dietary compliance CD patients.Sixty newly diagnosed (male/female: 43/17) 40 healthy subjects 23/17) were enrolled this study. diagnosis was established by...

10.3109/03009734.2011.581399 article EN cc-by Upsala Journal of Medical Sciences 2011-06-16

<i>Background/Aim:</i> Delay of laparoscopic cholecystectomy after the diagnosis biliary colic may increase probability recurrent emergency admission while awaiting elective cholecystectomy. The aim this study was to compare possible advantages and safety urgent (ULC) with (ELC) in patients colic. <i>Patients Methods:</i> Between 2001 2003, 75 were included study. classified into following two groups: who had ULC 24 h group I (n = 28) ELC (mean interval 4.22 ± 1.42...

10.1159/000085300 article EN Digestive Surgery 2005-01-01

To report the third published case, as of April 8, 2006, methylprednisolone-induced toxic hepatitis.A 47-year-old woman was admitted to our clinic with weakness, fatigue, pruritus, and scleral icterus that had developed 10 days prior presentation. She been taking topiramate for one year treatment chronic isolated central nervous system vasculitis. One week before her symptoms developed, she completed a self-prescribed 7 day course oral methylprednisolone left arm weakness. believed...

10.1345/aph.1h171 article EN Annals of Pharmacotherapy 2006-08-23

Background: The exact etiology of irritable bowel syndrome (IBS) remains unclear. Curative treatment is not available and current modalities are mainly directed against the predominant symptoms. There a few studies reporting beneficial effects transcutaneous electrical stimulation in patients with chronic constipation, gastroparesis, functional dyspepsia. Aim: To investigate whether an effective procedure IBS patients. Methods: were randomly placed vacuum interferential (IFC) placebo groups....

10.1159/000338301 article EN Digestion 2012-01-01
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