A5037595072- Pituitary Gland Disorders and Treatments
- Growth Hormone and Insulin-like Growth Factors
- Adrenal and Paraganglionic Tumors
- Thyroid Cancer Diagnosis and Treatment
- Adrenal Hormones and Disorders
- Diet and metabolism studies
- Neuroendocrine Tumor Research Advances
- Medical Imaging and Pathology Studies
- Thyroid Disorders and Treatments
- Sexual Differentiation and Disorders
- Bone health and treatments
- Thyroid and Parathyroid Surgery
- Parathyroid Disorders and Treatments
- Neuroblastoma Research and Treatments
- Genetic Syndromes and Imprinting
- Glutathione Transferases and Polymorphisms
- Hormonal and reproductive studies
- Viral Infections and Vectors
- Diabetic Foot Ulcer Assessment and Management
- Vitamin D Research Studies
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Intestinal Malrotation and Obstruction Disorders
- Gastroesophageal reflux and treatments
- Myofascial pain diagnosis and treatment
- Glioma Diagnosis and Treatment
University of Health Sciences
2024
Sağlık Bilimleri Üniversitesi
2024
University of Health Sciences Antigua
2024
Istanbul Medipol University
2014-2022
Sivas State Hospital
2016
Sivas Cumhuriyet Üniversitesi
2006-2015
Erciyes University
1999-2000
Sheehan's syndrome occurs as a result of ischemic pituitary necrosis due to severe postpartum hemorrhage. The aim the present study was determine clinical characteristics in 20 patients (mean age 60.15 +/- 3.41 years) with typical obstetric history. mean duration between time diagnosis and date last delivery 26.82 2.52 years (range 2-40 years). All had history massive hemorrhage at physical signs syndrome. Fourteen (70.0%) lacked milk production did not menstruate following delivery....
It has been shown that miRNA 221, 222 and 146b are increasingly expressed while p27(Kip1) is suppressed in papillary thyroid cancer (PTC).We investigated the association between disease recurrence risk expression of 222, protein mRNA these tumors. We also measured changes miRNAs presence Hashimoto's thyroiditis (HT).We examined formalin fixed tissue samples obtained from 77 patients. 11 out were identified as well differentiated tumor with uncertain malignant potential (WDT-UMP), 46 PTC 20...
The short ACTH stimulation test is an easy, reliable, and extensively used in the assessment of hypothalamo-pituitary- adrenal (HPA) axis. However, its use immediately after pituitary surgery a matter debate. insulin tolerance (ITT) gold standard evaluation HPA axis, but it not always without side effects may be unpleasant early surgery. Our aim was to investigate value 1-μg axis We also aimed determine 250-μg tests ITT estimation status 3 months postoperatively. Nineteen patients subjected...
Extent of thyroidectomy in the management benign thyroid disease remains controversial. In this clinical study, three different techniques were compared by means complication, short period recurrence and L-thyroxin requirement rates. Two hundred consecutive patients who had bilateral subtotal (BST) (n = 71), unilateral total lobectomy + contralateral (Dunhill Procedure (DP)) or (TT) 58) for disorders included study. One patient was re-operated due to bleeding BST group. Wound infection...
<b>Introduction:</b> Radioactive iodine (RAI) ablation treatment is used for patients diagnosed with well-differentiated thyroid cancer in order to reduce the risk of recurrence. RAI can adversely affect gonads males and females. In this study, we aimed determine ovary damage infertility due RAI, using serum anti-Müllerian hormone (AMH) level, females who received treatment. <b>Materials Methods:</b> 45 female have not gone through menopause had premenopausal period, 40 healthy as control...
Normosmic idiopathic hypogonadotropic hypogonadism (nIHH) is characterized by failure of initiation or maintenance puberty due to insufficient gonadotropin release, which not associated with anosmia/hyposmia. The objective this study was determine the distribution causative mutations in a hereditary form nIHH.In prospective collaborative study, 22 families more than one affected individual (i.e. multiplex families) nIHH were recruited and screened for genes known suspected be strong...
The prevalence of non-classic adrenal hyperplasia (NCAH) among Turkish women with hirsutism has not been established so far. Thus, we aimed to evaluate the 21-hydroxylase (21-OH) deficiency by ACTH stimulation test hirsute women. study population consisted 285 premenopousal women, aged 16–46 years (mean: 23.2 ± 0.3). All were and hyperandrogenic. Androgen secreting tumors ovaries glands excluded as well thyroid dysfunction hyperprolactinemia. patients evaluated 0.25 mg (i.v.) 17-OHP...
The primary aim of the study was to compare efficacy Oct-LAR and surgery in terms controlling IGF-1 GH levels tumour volumes. second two treatment modalities side effects such as pituitary insufficiency, cholelithiasis, metabolic parameters effect on quality life (QoL).The a randomized, prospective study.The 22 patients were consecutively randomized surgical groups.Baseline serum level, volume comparable groups. No significant differences detected between groups at 3rd 6th months, but 12th...
Abstract Objective Sclerostin is an osteocyte-secreted endogenous inhibitor of Wnt signaling. Several systemic and local factors have been suggested as possible regulators sclerostin expression by osteocytes. In this study, we examined the effect vitamin D treatment on levels. Subject Methods 44 patients with diagnosis deficiency (25(OH)D≤20 ng/ml) were involved in study. Patients had monthly intramuscular injection 300.000 IU cholecalciferol for 3 consecutive months. Sclerostin, 25(OH)D,...
This study was set up to investigate the relationship between immune process and high levels of human chorionic gonadotropin-beta (betahCG) in hyperemesis patients with or without hyperthyroxinemia.betahCG, parameters thyroid related hormones were assayed controls.Mean serum betahCG, fT4 TSH significantly higher than controls (p<0. 01, p<0.01, p<0.05, respectively). Further, regarding IgG, IgM, C3, C4 lymphocyte count (p<0.05, In hyperthyroxinemia, mean IgG IgM women hyperthyroxinemia...
The relationship of leptin to diminished appetite and weight loss has been investigated in many diseases. Diminished are the most apparent characteristics patients with active lung tuberculosis this study relation such before after treatment. Twenty‐five (7 female, 18 male) having an age range 18–70 years (mean 47.48 ± 15.36 y) 25 normal individuals (9 16 25–71 44.60 13.80 were included study. Leptin levels, body mass index (BMI), fat ratio (BFR), waist hip (WHR) measured 6 months...
Abstract We investigated the effect of long‐term exposure to modulation magnetic field (MF), insulin, and their combination on blood–brain barrier (BBB) permeability in a diabetic rat model. Fifty‐three rats were randomly assigned one six groups: sham, exposed no MF; MF, diabetes mellitus (DM), DM induced with streptozotocin (STZ); plus MF (DMMF); insulin therapy (DMI); (DMIMF). All underwent Evans blue (EB) measurement evaluate BBB 30 days after beginning experiments. The DMMF, DMIMF groups...
This study investigated whether symptoms and findings of hyperthyroidism exist in patients with subclinical (SCH) sought to determine treatment improves them. Twenty (mean age: 36.10 +/- 1.41 years) 20 healthy controls [mean 36.35 1.50 were included the study. The SCH duration was at least 6 months. Bone mineral density (BMD) measured both controls. randomly divided into 2 groups 10 each. Symptoms evaluated BMD, 24 hour ambulatory blood pressure, holter measurements serum lipids determined...
Platelet abnormalities in diabetes mellitus (DM) and atrial fibrillation (AF) may underline the etiology of a prothrombotic state these conditions. Increased mean platelet volume (MPV) is marker abnormal function activation. We aimed to investigate possible association chronic AF with MPV patients who have type 2 DM. Patients had DM either (≥6 months) or normal sinus rhythm (NSR) were included study. A total 162 (aged 38–89 years) divided into groups according presence NSR. Group 1 consisted...
In addition to tumor size, it has been suggested that P-glycoprotein (P-gp) expression and/or oxyphilic cell content in parathyroid adenomas an important influence on the results of technetium 99m methoxyisobutylisonitrile (Tc-99m MIBI) imaging.In this study, we compared MIBI imaging and immunohistochemical analysis (IHA) P-gp expression, content, tumoral tissue volume adenomas. We also evaluated relationship between ultrasound (US) results, operation findings, serum biochemical values.Forty...