Zekiye Hasbek

ORCID: 0000-0002-8119-3363
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About
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Research Areas
  • Thyroid Cancer Diagnosis and Treatment
  • Medical Imaging Techniques and Applications
  • Medical Imaging and Pathology Studies
  • Radiomics and Machine Learning in Medical Imaging
  • Radiopharmaceutical Chemistry and Applications
  • Prostate Cancer Treatment and Research
  • Hematological disorders and diagnostics
  • Radiation Dose and Imaging
  • Cardiac Imaging and Diagnostics
  • Galectins and Cancer Biology
  • Cancer Diagnosis and Treatment
  • Thyroid Disorders and Treatments
  • Renal and Vascular Pathologies
  • Orthopedic Infections and Treatments
  • Cancer, Lipids, and Metabolism
  • Chronic Kidney Disease and Diabetes
  • Biomarkers in Disease Mechanisms
  • Lung Cancer Treatments and Mutations
  • Parathyroid Disorders and Treatments
  • Salivary Gland Tumors Diagnosis and Treatment
  • Thyroid and Parathyroid Surgery
  • Advanced MRI Techniques and Applications
  • Cancer, Hypoxia, and Metabolism
  • Cancer-related Molecular Pathways
  • Antifungal resistance and susceptibility

Sivas Cumhuriyet Üniversitesi
2016-2025

Sivas State Hospital
2015-2023

Yüksek İhtisas Üniversitesi
2016

Çanakkale Onsekiz Mart Üniversitesi
2014

Kayseri Eğitim ve Araştırma Hastanesi
2013

Kahramanmaraş Sütçü İmam University
2009

Objectives: This study aimed to evaluate the relationship between degree of bone marrow involvement, hematological parameters, and 18 F-fluorodeoxyglucose ( F-FDG)-positron emission tomography/computed tomography (PET/CT) data in patients diagnosed with multiple myeloma.Methods: A total 71 [19 females, 52 males, mean age 67 (36-83) years] who were myeloma 2014 2021, had not received any treatment yet, underwent F-FDG-PET/CT for staging included study.Results: No significant correlation was...

10.4274/mirt.galenos.2024.78557 article EN Molecular Imaging and Radionuclide Therapy 2025-01-22

This study aimed to determine the demographical distribution, survival and prognostic factors for neuroendocrine tumors monitored in our clinic.Data 52 patients who were admitted Cumhuriyet University Medical Faculty Training Research Practice Hospital Oncology Center between 2006 2012 diagnosed treated investigated.Of total, 30 (58%) females 22 (42%) males. The localization of disease was gastroenteropancreatic 29 (56%) other sites 23 (44%). most frequently involved organ system stomach...

10.7314/apjcp.2013.14.11.6687 article EN cc-by Asian Pacific Journal of Cancer Prevention 2013-11-30

Epigenetic alterations in the global DNA methylation status may be associated with an increased risk of some cancer types humans. The methylenetetrahydrofolate reductase (MTHFR) gene is involved folic acid metabolism and plays essential role inherited profiles. common 677 C>T 1298 A>C polymorphisms MTHFR cause production a thermolabile enzyme reduced function and, eventually, genomic hypomethylation. current preliminary study was designed to determine association between germ-line...

10.1089/gtmb.2011.0347 article EN Genetic Testing and Molecular Biomarkers 2012-04-26

Background: Osteoporosis is a widespread metabolic bone disease representing global public health problem currently affecting more than two hundred million people worldwide. The World Health Organization states that dual-energy X-ray absorptiometry (DXA) the best densitometric technique for assessing mineral density (BMD). DXA provides an accurate diagnosis of osteoporosis, good estimation fracture risk, and useful tool monitoring patients undergoing treatment. Common mistakes in BMD testing...

10.14712/18059694.2017.38 article EN cc-by Acta Medica (Hradec Kralove Czech Republic) 2016-01-01

Typically, bone metastasis causes osteolytic and osteoblastic lesions resulting from the interactions of tumor cells with osteoclasts osteoblasts. In addition to these interactions, tissues may grow inside bones cause mass lesions. present study, we aimed demonstrate negative impact a in large cohort patients metastatic cancer.Data 335 metastases were retrospectively reviewed. For analysis, all divided into three subgroups respect type metastasis: osteolytic, osteoblastic, or mixed. The...

10.6061/clinics/2015(08)01 article EN cc-by Clinics 2015-08-01

Introduction: This study aimed to evaluate the relationship between pathological and clinical risk classifications in newly diagnosed prostate cancer patients, 68Ga-PSMA PET/CT data serum Prostate Specific Antigen (PSA) values. Method: A total of 203 patients who were with 2019 2023, had not yet received treatment underwent for staging purposes included this study. Results: There was a substantial correlation D’Amico classification, Gleason score, ISUP presence or absence metastasis (p <...

10.3390/curroncol31090391 article EN cc-by Current Oncology 2024-09-08

In addition to tumor size, it has been suggested that P-glycoprotein (P-gp) expression and/or oxyphilic cell content in parathyroid adenomas an important influence on the results of technetium 99m methoxyisobutylisonitrile (Tc-99m MIBI) imaging.In this study, we compared MIBI imaging and immunohistochemical analysis (IHA) P-gp expression, content, tumoral tissue volume adenomas. We also evaluated relationship between ultrasound (US) results, operation findings, serum biochemical values.Forty...

10.1089/cbr.2006.21.579 article EN Cancer Biotherapy and Radiopharmaceuticals 2006-12-01

Objectives: This study aimed to evaluate the relationship between mobile phone usage and miRNA-574-5p miRNA-30C-5p levels in patients diagnosed with differentiated thyroid cancer (DTC).Methods: Fifty DTC 50 healthy volunteers were included study.miRNA-574-5p gene expression blood of all subjects analyzed by real time-polymerase chain reaction, a questionnaire including various questions was administered both groups.Results: Although there 7.60-fold increase patient group compared control...

10.4274/mirt.galenos.2023.04880 article EN Molecular Imaging and Radionuclide Therapy 2024-02-23

Objectives: In this study, we measured hearing thresholds in patients diagnosed with hyperthyroidism or hypothyroidism high-frequency audiometry and otoacoustic emission before after treatment to determine whether losses were cochlear retrocochlear they would improve medical therapy. Materials Methods: This study was conducted on at Cumhuriyet University, Faculty of Medicine, Department Endocrinology Metabolism accepting participate the study. We population during pretreatment period...

10.4103/0971-7749.155310 article EN Indian Journal of Otology 2015-01-01

Serum thyroglobulin detection plays an essential role during the follow-up of thyroid cancer patients treated with total/near total thyroidectomy and radioiodine ablation. The aim this retrospective study was to evaluate relationship between stimulated serum (Tg) level at time high dose 131I ablation risk recurrence, using a three-level classification in differentiated (DTC) according ATA guidelines. Also we investigated postoperative Tg DxWBS results 8-10 months thereafter.Patients...

10.7314/apjcp.2014.15.6.2523 article EN cc-by Asian Pacific Journal of Cancer Prevention 2014-03-30

Atelectasis is an important prognostic factor that can cause pleuritic chest pain, coughing or dyspnea, and even may be a of death. In this study, we aimed to investigate the potential impact atelectasis PET parameters on survival relation between parameters.The study consisted patients with lung cancer without who underwent (18)F-FDG PET/CT examination before receiving any treatment. derived including tumor size, SUVmax, SUVmean, MTV, total lesion glycosis (TLG), SUV mean area, volume,...

10.7314/apjcp.2014.15.9.4085 article EN cc-by Asian Pacific Journal of Cancer Prevention 2014-05-15

Without appropriate control measures, contrast-induced nephropathy (CIN) incidence has been claimed to be overestimated.To evaluate the relationship and difference between differential serum creatinine (DsCr), which is currently surrogating as a marker of CIN, measured GFR values measure (DGFR) in hospitalized patients.GFR was two times by Tc-99m DTPA, before 48 h after contrast media (CM), along with sCr BUN 35 inpatients (22 men, 13 women, mean age ± SD = 61 14) no known chronic kidney...

10.1258/ar.2011.110412 article EN Acta Radiologica 2011-12-03

Remnant ablation with radioactive iodine (I-131) is a successful form of treatment that aims to destroy the remaining residual tissue and/or metastatic after total thyroidectomy in differentiated thyroid cancer (DTC) patients. High level stimulating hormone (TSH) (≥30 mIU/L) recommended for success treatment. In this retrospective study, our aim was investigate whether TSH levels at time effect remnant ablation.Patients who were diagnosed DTC, treated bilateral total/near and referred I-131...

10.4274/mirt.88598 article TR Molecular Imaging and Radionuclide Therapy 2016-06-01

Objective: Mutations in the p53 gene are most commonly observed genetic abnormalities malignancies.The purpose of this study was to assess diagnostic value serum anti-p53 antibody (Ab) along with correlation between Ab level and quantitative positron emission tomography (PET) parameters such as maximum standardized uptake (SUV max ), SUV ave , metabolic tumor volume, total lesion glycolysis (TLG) size.Methods: Serum studied three groups.Patients who underwent 18 F-fluorodeoxyglucose (FDG)...

10.4274/mirt.97269 article EN Molecular Imaging and Radionuclide Therapy 2016-09-29

In plastic surgery practice, fasciocutaneous single-perforator-pedicled propeller flap is a preferred procedure; however, its survival rate below than expected, especially in flaps with big rotation arc. When botulinum toxin-A injected into the muscle tissue that perforator pedicle arisen, tonus of pertinent can reduce and blood flow increase. Therefore this procedure improve flap.To evaluate effect ultrasonographic guidance arisen from one month ago on perfusion scintigraphically rat...

10.4274/balkanmedj.galenos.2019.2019.9.44 article EN cc-by-nc-nd Balkan Medical Journal 2020-02-27

The aim of the present study was to evaluate response treatment by histopathologic type in patients with lung cancer and under follow-up 18F-fluoro-2deoxy-glucose-positron emission tomography/computed tomography (18F-FDG PET/CT) imaging using Response Evaluation Criteria Solid Tumors (RECIST) European Organisation for Research Treatment Cancer (EORTC) criteria that morphologic metabolic parameters.On two separate (pre- post-treatment) 18F-FDG PET/CT images, longest dimension primary tumor as...

10.4274/mirt.36349 article TR Molecular Imaging and Radionuclide Therapy 2016-06-01

The aim of this study was to evaluate the myocardial viability in nondiabetic patients with chronic coronary artery disease (CCAD) or past infarction (MI), using thallium-201 infusion perfusion single-photon emission computed tomography (MPSPECT) imaging after oral glucose application (Glu+Tl-infusion).In study, 33 (three female, 30 male, mean age: 55.24+/-11 years, range: 33-77 years) MI history known CCAD were included. Rest/redistribution/24 h-late-MPSPECT performed for all patients. In...

10.1097/mnm.0b013e32832c79b6 article EN Nuclear Medicine Communications 2009-08-30

Miyokardial Perfüzyon Görüntüleme SPECT Parametreleri ve Adenozin ile Yapılan Farmakolojik Stres Testinin Koroner Anjiyografi Bulguları Değerlendirilmesi, Tanı Uyumu Var

10.4274/mirt.galenos.2019.47450 article TR Molecular Imaging and Radionuclide Therapy 2019-06-01

Introduction: Radioiodine ablation refers to the destruction of functioning remnants normal thyroid tissue or metastatic foci remaining after thyroidectomy. Effective requires adequate stimulation thyroid-stimulating hormone. Our aim in this study was evaluate hearing changes patients before therapy iatrogenic hypothyroid period, which has been constituted with purpose treatment success and following euthyroid period 1 month hormone (TH) replacement initiated. Materials Methods: Patients who...

10.4103/0971-7749.146937 article EN Indian Journal of Otology 2014-01-01

Human epidermal growth factor receptor-2 (HER-2) is a protooncogene encoded by ERBB2 on chromosome 17. 18Fluoridefluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) examination frequently used to detect distant metastasis in gastric cancer imaging. This study aimed investigate the relationship between data obtained 18F-FDG PET/CT and HER-2 expression status patients with cancer.A total of 115 diagnosed 2016 2020, immunohistochemical followed for staging...

10.4274/mirt.galenos.2021.78055 article TR Molecular Imaging and Radionuclide Therapy 2021-10-01

ALP and LDH are serum markers of prognostic importance in prostate cancer patients. PET/CT imaging with Ga-68 PSMA has played an important role recent years. Our aim this study was to evaluate the relationship significance between SUVmax values obtained levels patients.We retrospectively evaluated 61 patients who had did not have a prostatectomy 2019 2020. PSA, were measured all before or after within maximum 28 days.The median age included 73 (range: 57-89) prostatic adenocarcinoma. 50...

10.37554/en-j.arch.esp.urol-20210903-3536-35 article EN 2021-09-03

The aim of this study was to evaluate the sensitivity 18F-FDG (fluorodeoxyglucose) PET/CT (positron emission tomography / computed tomography) imaging performed for primary staging prior surgery with low anterior resection technique in detecting presence lymph node metastases detected mesorectal area. In our retrospective study, 44 patients who were operated colorectal cancer Surgical Oncology Department between June 15, 2015 and 2020 underwent preoperative included. demographic data...

10.46683/jmvi.2024.89 article EN Journal of Molecular Virology and Immunology 2024-04-12

Introduction: Obesity and aggressive prostate cancer are two important clinical conditions because of the prevalence obesity increases aggressiveness cancer. In this study, our aim was to investigate rates at time diagnosis in patients who underwent Ga-68 PSMA PET/CT. Materials methods: 104 with newly diagnosed PET/CT between 2021 2022 for staging were included study. The patients' height weight, pathology results PSA values, which recorded routinely before PET/CT, obtained from Nuclear...

10.7197/cmj.1186002 article EN Cumhuriyet Tıp Dergisi/Cumhuriyet Üniversitesi Tıp Fakültesi dergisi 2024-05-14
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