A5012683721- Lung Cancer Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Cancer Diagnosis and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Inflammatory Biomarkers in Disease Prognosis
- Cancer Treatment and Pharmacology
- Radiomics and Machine Learning in Medical Imaging
- Management of metastatic bone disease
- Uterine Myomas and Treatments
- Lung Cancer Treatments and Mutations
- HER2/EGFR in Cancer Research
- Cancer, Hypoxia, and Metabolism
- Metastasis and carcinoma case studies
- Endometriosis Research and Treatment
- Effects of Radiation Exposure
- Advanced Radiotherapy Techniques
- Hepatocellular Carcinoma Treatment and Prognosis
- Renal cell carcinoma treatment
- RNA modifications and cancer
- Cancer-related Molecular Pathways
- Peptidase Inhibition and Analysis
- Pituitary Gland Disorders and Treatments
- Adrenal and Paraganglionic Tumors
- Endometrial and Cervical Cancer Treatments
- Cancer, Lipids, and Metabolism
Bursa Yuksek Ihtisas Egitim Ve Arastirma Hastanesi
2018-2024
Atlas Üniversitesi
2024
Sağlık Bilimleri Üniversitesi
2020-2024
Istanbul Arel University
2024
Bursa Technical University
2022-2023
University of Health Science
2022
University of Health Sciences
2022
Sivas Cumhuriyet Üniversitesi
2012-2018
Afyon Kocatepe University
2016-2018
State Hospital
2016
Although many prognostic factors have been identified for lung cancers, new ones are needed to determine the course of disease. Recently, a high neutrophil lymphocyte ratio (NLR) prior surgery or treatment has shown be an indicator prognosis cancer. The aim this study was investigate value NLR as factor and correlation between other probable clinical in non small cell cancer patients treatment.Data who were diagnosed with non-small our institution retrospectively reviewed. Demographic...
Background: Hepatocellular cancer (HCC) is one of the important health problems in Turkey, being very common and highly lethal. The aim this study was to determine clinical, demographic features risk factors. Materials Methods: Nine hundred sixth-three patients with HCC from 13 cities Turkey were included study. Results: Only 205 (21%) 963 women, a male:female predominance 4.8:1 median age 61 years. etiologic factors for hepatitis B 555 (57.6%), 453 (81%) men, 102 (19%) again male...
This study aimed to determine the demographical distribution, survival and prognostic factors for neuroendocrine tumors monitored in our clinic.Data 52 patients who were admitted Cumhuriyet University Medical Faculty Training Research Practice Hospital Oncology Center between 2006 2012 diagnosed treated investigated.Of total, 30 (58%) females 22 (42%) males. The localization of disease was gastroenteropancreatic 29 (56%) other sites 23 (44%). most frequently involved organ system stomach...
In spite of progress in treatment on colorectal cancer, it is not still convincing. Because that, there a pursuit to find better option. Our goal this study research antiproliferative effect and mechanism action sorafenib cancer cell line. Antiproliferative effects have been evaluated by using DLD-1 Materials Methods: For determining the cell, Real time analysis was performed. Chorioallantoic membrane model (CAM) used for assessing angiogenesis. Different concentrations (500, 250, 125, 62.5,...
Introduction Mammalian target of rapamycin is a pathway to block apoptosis. Recent studies showed that the activity mammalian increases in endometriotic lesions. Aim present study was effect everolimus agent, analog, an experimental endometriosis model. Materials and Methods Endometriosis established by autotransplantation uterine tissue peritoneal cavity confirmed 24 rats. The animals were then randomly divided into three groups receive either (1.5 mg/kg/day, p. o.), anastrozole (0.004...
In this study, it was aimed to investigate the relationship between diabetes and breast cancer detection of enzymes ornithine levels in polyamine synthesis pathway diabetes, diabetic patients.Ornithine, arginine decarboxylase, decarboxylase agmatinase have been measured serum all groups. Ornithine were spectrophotometrically. Arginine determined by ELISA kits.Except for group, increased statistically significant (P < 0.05). The increase very important among 0.001).Decreased synthase mellitus...
Typically, bone metastasis causes osteolytic and osteoblastic lesions resulting from the interactions of tumor cells with osteoclasts osteoblasts. In addition to these interactions, tissues may grow inside bones cause mass lesions. present study, we aimed demonstrate negative impact a in large cohort patients metastatic cancer.Data 335 metastases were retrospectively reviewed. For analysis, all divided into three subgroups respect type metastasis: osteolytic, osteoblastic, or mixed. The...
Although cutaneous metastasis occurs usually at the terminal stage of disease, it may be rarely concurrent with diagnosis and also present as first sign illness. A 55-year-old male patient presented vasculitic-type nodular lesions a necrotic distal phalangeal lesion developed over last month. He was tradesman smoked 40 packets year. On physical examination, he found to have multiple on skin face, limbs, neck, scalp, dorsal side, fingers, subungual right leg, feet. punch biopsy performed...
Acute kidney injury is an important issue in chemotherapy receiving patients neutrophil gelatinase-associated lipocalin has been proposed as a novel marker. We here aimed to assess the role of urinary levels for assessment after platin exposure.Patients who had treated with cisplatin or carboplatin oxaliplatin containg regimens were included this study. Baseline and postchemotherapy serum urea, creatinine, urine creatinine determined. To avoid effects hydration during infusion...
Background: In this case-control study, we aimed to investigate the relationship between methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and lung cancer. Materials Methods: Total 200 individuals including 100 patients with cancer controls were analyzed. Genotyping of MTHFR was performed using PCR RFLP methods. Results: The majority men 90% smokers. We found that risk ratio for development LC 13-times higher in smokers compared non-smokers patient control groups our study...
Objective of this study is to evaluate the association neck circumference and wrist with traditional abdominal general obesity measurement parameters, insulin resistance, resistance-related factors such as blood lipids, fasting glucose, concentration adiponectin, in order predict their values parameters. Eighty six female 20 male subjects between 18-75 years age were included study. Body weight, height, waist, hip, circumferences measured. mass index waist-to-hip ratio calculated. Laboratory...
Oxaliplatin is an effective and widely used chemotherapeutic agent in the treatment of many solid tumors. The most common side effects are peripheral neuropathy, gastrointestinal toxicity, neutropenia. There have been some case reports about ototoxicity with oxaliplatin, but no clinical trials. In this trial, we explored whether or not oxaliplatin has ototoxic effects. Materials methods: A total 18 patients, 14 colorectal cancer 4 pancreatic cancer, were included study. Four patients (22%)...
Background: Breast cancer evolution and tumor progression are controlled by complex interactions between steroid receptors growth factor receptor signaling. Aberrant signaling can augment or suppress estrogen function in hormone-dependent breast cells. Thus, we aimed to investigate antitumor effects of sorafenib lapatinib alone combination on MCF-7 Materials Methods: Cytotoxicity the was tested cells XTT assays. 50, 25, 12.5 <TEX>$6.25{\mu}M$</TEX> concentrations 200, 100, 50...
Lung cancer is the most common cause of cancer-related death worldwide. The incidence lung aproximately 7-8 thousand percent in Turkish women. In this study, we aimed to evaluate clinical, pathological properties and survival data female patients with who were treated our center.From 2007 2012, 50 women enrolled. Patient evaluated retrospectively.The median age was 61 (40-81). Forty (80%) diagnosed non small cell (NSCLC), 10 (20%) carcinoma (SCC). Twelve (24%) smokers 13 16 non-smokers had a...
Atelectasis is an important prognostic factor that can cause pleuritic chest pain, coughing or dyspnea, and even may be a of death. In this study, we aimed to investigate the potential impact atelectasis PET parameters on survival relation between parameters.The study consisted patients with lung cancer without who underwent (18)F-FDG PET/CT examination before receiving any treatment. derived including tumor size, SUVmax, SUVmean, MTV, total lesion glycosis (TLG), SUV mean area, volume,...
Further elucidation of the molecular mechanisms underlying lung cancer (LC) is essential for development new effective therapeutic agents. Recently, involvement Wnt antagonists in oncogenesis has been demonstrated several cancers. The investigation their contribution to carcinogenesis still under investigation. We aimed investigate whether there a susceptibility or preventive effect antagonist gene polymorphisms on and/or prognosis LC. investigated 110 LC patients and 160 controls....
To investigate the role of surgical resection primary tumor on overall survival (OS) in advanced gastric cancer patients at time diagnosis.The rates metastatic whose was resected diagnosis were compared with nonresected.The median progression-free and OS operated nonoperated group 10 versus 6, 14 9 months, respectively (p < 0.001). In multivariate analysis, tumor, Eastern Cooperative Oncology Group performance status, second-line chemotherapy had a significant effect (hazard ratio [HR]: 0.52...
<b>Background/Aims:</b> This study aimed to examine whether UHRF-1 and p53 overexpression is a prognostic marker for gastric cancer. <b>Patients Methods:</b> Sixty-four patients with cancer (study group) 23 gastritis (control were evaluated. Immunohistochemistry was used expression of in cancers control group diagnosed gastritis. <b>Results:</b> The median age 63 years (18-83 years) the group. positive 15 (23%) fi ve (21.7%) (<i>P</i> = 0.559). UHRF1 level more powerful than 0.046)....
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Avcı N, Hartavi M, Kaçan T, et al. Retrospective analysis of the microbiological spectrum pneumonia in Turkish patients with lung cancer. Contemporary Oncology/Współczesna Onkologia. 2016;20(1):63-66. doi:10.5114/wo.2016.58502. APA Avcı, N., Hartavi, M., Kaçan, T., Bayındır, & Özakın, C. (2016). Onkologia, 20(1), 63-66. https://doi.org/10.5114/wo.2016.58502 Chicago Nilüfer, Mustafa Turgut Murat Cüneyt and Aynur...
The lung is a common location for malignant metastases. However, endobronchial metastases from nonpulmonary neoplasms are rare. Metastatic breast cancer usually occurs in 2-3 years of the disease course. A 65-year-old woman visited our hospital evaluation dry cough. patient had history cancer, which was treated with modified radical mastectomy and axillary dissection 10 ago; she then aromatase inhibitor 5 years. Chest X-ray revealed right hilum enlargement. Thorax computed tomography 35-mm...