- Lung Cancer Treatments and Mutations
- Breast Cancer Treatment Studies
- Cancer Immunotherapy and Biomarkers
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Treatments and Studies
- Advanced Breast Cancer Therapies
- Estrogen and related hormone effects
- Lung Cancer Research Studies
- Cancer Treatment and Pharmacology
- Renal cell carcinoma treatment
- HER2/EGFR in Cancer Research
- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Radiomics and Machine Learning in Medical Imaging
- Cancer, Lipids, and Metabolism
- Cancer survivorship and care
- Sulfur Compounds in Biology
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer-related Molecular Pathways
- Nutrition and Health in Aging
- Cancer Genomics and Diagnostics
- Multiple and Secondary Primary Cancers
- Cancer Risks and Factors
- Lung Cancer Diagnosis and Treatment
- Glutathione Transferases and Polymorphisms
Memorial Ankara Hospital
2023-2025
Ankara Bilkent City Hospital
2024-2025
Ankara Yıldırım Beyazıt University
2016-2025
Ankara Mevki Asker Hastanesi
2023
Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi
2008-2022
Ankara Onkoloji Eğitim ve Araştırma Hastanesi
2016
Ankara Atatürk Eğitim ve Araştırma Hastanesi
2013-2016
Ankara Numune Eğitim ve Araştırma Hastanesi
2011-2013
Istanbul University
1994
Central nervous system (CNS) metastases can be seen at a rate of 30% in advanced stages for patients with non-small cell lung cancer (NSCLC). Growing evidence indicates the predictive roles driver gene mutations development brain (BM) recent years, meaning that oncogene-driven NSCLC have high incidence BM diagnosis. Today, 3rd generation targeted drugs intracranial efficacy, which cross blood-brain barrier, made positive contribution to survival these an increased propensity BM. It is...
Purpose: CDK4/6 inhibitors require meticulous monitoring due to their potential cause hematological toxicities and hepatotoxicity. This study evaluates the safety of combining with palliative radiotherapy in patients metastatic hormone receptor-positive HER2-negative breast cancer. Patients Methods: included 188 treated between January 2021 June 2024. Data on patient demographics, tumor characteristics, treatment interventions were extracted from medical records. The primary focus was...
Background: Medication errors in oncology may cause severe clinical problems due to low therapeutic indices and high toxicity of chemotherapeutic agents.We aimed investigate unintentional medication underlying factors during chemotherapy preparation administration based on a systematic survey conducted reflect nurses experience.Materials Methods: This study was 18 adult units with volunteer participation 206 nurses.A developed by primary investigators (MAEs) defined preventable prescription...
Colorectal cancer (CRC) is one of the most common cancers worldwide and survival still approximately 24 months. Recently, importance molecular features, tumor localization, also inflammatory status increased, these entities can be used as a predictive marker for colon tumor. However, since tests are expensive unachievable, there need new prognostic markers that easily inexpensive.We aimed to investigate effect red cell distribution width (RDW)-to-platelet ratio (RPR) which reflects...
Gastric carcinomas are highly mortal neoplasms for which new therapeutic options being searched. The molecular subtyping of gastric adenocarcinomas was proposed recently, and the relationship between etiopathogenetic types is still under investigation. Here we compared histopathologic, prognostic, survival differences Epstein-Barr virus (EBV)-positive Her2-positive adenocarcinomas. In a retrospective design, searched EBV status with Epstein Barr Virus encoded small RNA (EBER) in situ...
Background: Utilizing geriatric screening tools for the identification of vulnerable older patients with cancer is important.The aim this study to evaluate hospitalization risk elderly hematologic based on assessment and laboratory parameters.Materials Methods: In cross sectional 61 malignancies, age 65 years older, were assessed at a hematology outpatient clinic.Standard tests; activities daily living (ADL), instrumental (IADL), Mini Nutritional Assessment (MNA), Mental State Examination...
Background: Breast cancer (BC) is the one of most common cancers in women. It also a leading cause death. Unfortunately, some patients initially present with distant metastases and are diagnosed stage IV disease that nearly always, by then, incurable. This retrospective analysis investigated risk factors for BC may underlie such late presentation. Materials Methods: In all, 916 who visited medical oncology polyclinic eight different centres Turkeybetween December 2011 January 2013 were...
The addition of aflibercept to the fluorouracil and irinotecan (FOLFIRI) regimen significantly improved clinical outcomes in patients with metastatic colorectal cancer (CRC) previously treated oxaliplatin. We aimed investigate efficacy safety second-line FOLFIRI combination CRC real-life experience.
<b>Background/Aims:</b> This study aimed to examine whether UHRF-1 and p53 overexpression is a prognostic marker for gastric cancer. <b>Patients Methods:</b> Sixty-four patients with cancer (study group) 23 gastritis (control were evaluated. Immunohistochemistry was used expression of in cancers control group diagnosed gastritis. <b>Results:</b> The median age 63 years (18-83 years) the group. positive 15 (23%) fi ve (21.7%) (<i>P</i> = 0.559). UHRF1 level more powerful than 0.046)....
Gastric cancer is one the most diagnosed and third leading cause of death from worldwide. As an indicator antioxidant capacity thiol/disulfide homeostasis regulates detoxification, cell signal mechanisms, apoptosis, transcription defense mechanisms. Disregulation identified in other types by recent data. In this study, we aimed to evaluate advanced gastric patients. The patients who with healthy control subjects were included study. Serum samples for thiol-disulphide test obtained at time...
Chest pain after thoracic trauma may be a symptom of cardiac injury or myocardial infarction. A 63-year-old healthy man had chest blunt in motor vehicle accident. computed tomography scan showed displaced sternal fracture, lung contusion the left upper lobe, atelectasis and consolidation both lower lobes, bilateral haemothorax. Electrocardiography ST elevation (2 mm) leads II, III, aVF depression I aVL, consistent with acute inferior Urgent coronary angiography ostial occlusion right artery....
Background: ABVD (doxorubicin, bleomycin, vinblastine (Vb) and dacarbazine) is the standard regimen in Hodgkin's lymphoma (HL).Vincristine (O) a mitotic spindle agent like Vb. We aimed to evaluate efficacy safety of O as part ABOD HL. Materials Methods: Patients who had were enrolled. Stage I-II HL evaluated for unfavorable risk factors according NCCN. National Cancer Institute Common Toxicity Criteria was used toxicity. Results: Seventy-nine patients our center between 2003 2007...