Dünya genelinde meydana gelen ölümlerin nedenleri arasında kanser ikinci sırada yer almaktadır. Gelişmekte olan tedavi yöntemleri ile hastalarının prognozunda olumlu yönde ilerleme kat edilmiş olsada vakaların büyük bir kısmında hala daha kötüdür. Antikanser tedavisine karmaşık yaklaşımlar araştırmacıları bu konuda da yeni yollar aramaya teşvik etmektedir. Bağırsak mikrobiyotası amaçla araştırılması gereken geniş alanlardan biridir. Mikrobiyotanın insan vücudunda önemli yeri vardır....

Background: Inflammatory hematological parameters like the neutrophil/lymphocyte (N/L) ratio have been investigated in many cancer types and significant relationships found with prognosis, for example. The aim of this present study was to investigate impact notably on N/L mean platelet volume (MPV) papillary thyroid cases. Materials Methods: A total 79 patients who underwent a thyroidectomy operation Findikli, Goiter Research Treatment Center during 2011-2015 period were enrolled study, 41...

Restless legs syndrome (RLS), also known as Willis-Ekbom disease, is characterised by abnormal sensations in the well dysaesthesia. Although aetiology of RLS has not yet been determined, it may be associated with systemic inflammation. The neutrophil-to-lymphocyte ratio (NLR) a new and simple marker indicating present study aimed to investigate relationship between inflammation through use NLR. A total 75 newly diagnosed patients 56 healthy control subjects were included study. Baseline NLR...

Vitamin D deficiency is frequently seen in patients with polycystic ovary syndrome (PCOS) and has been shown to exhibit multiple effects on the disease process. The purpose of this study was investigate role vitamin complex PCOS pathophysiological pathways.Two hundred sixty-seven were divided into two groups Group 1 25(OH)D3 deficiency, 2 normal 25(OH)D3. Biochemical hormonal parameters (androgen hormones, gonadotropins, thyroid function tests) compared between groups.Eighty-six percent...

This study investigates whether C-reactive protein, platelet-lymphocyte ratio, and neutrophil-lymphocyte ratio could be useful to predict mortality in COVID-19.Data of 635 patients with COVID-19 followed up Sinop Ataturk State Hospital from February May 2020 were evaluated retrospectively. Diagnosis was made according the interim guidance World Health Organization. Patients grouped into two groups based on as survived non-survived patients. Age, gender, protein investigated compared.The mean...

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)

Objective: To investigate the impacts of demographic, hematological, and biochemical factors on clinical course prognostic outcome in adult COVID-19 patients. Methods: This retrospective study was performed internal medicine departments 2 hospitals data were extracted from medical files 1700 patients (836 females, 49.2%; 864 males, 50.8%) with an average age 48.23 ± 16.68 (range: 18-93). Clinical included baseline descriptives, prior history, admission date, treatment, hematological blood...

Background: Breast cancer (BC) is the one of most common cancers in women. It also a leading cause death. Unfortunately, some patients initially present with distant metastases and are diagnosed stage IV disease that nearly always, by then, incurable. This retrospective analysis investigated risk factors for BC may underlie such late presentation. Materials Methods: In all, 916 who visited medical oncology polyclinic eight different centres Turkeybetween December 2011 January 2013 were...

Hashimoto's thyroiditis (HT) is a common autoimmune disorder. Genetic, environmental, and immunological factors all play role in the pathogenesis of HT, but effects lymphocytes platelets on pathophysiology HT are still unknown. In this study, we evaluated neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte (PLR), mean platelet volume (MPV) groups subgroups with low cardiovascular risks.This study included 92 patients 38 control subjects. Among patients, three were formed according...

To investigate anxiety, depression, and Obsessive-Compulsive Disorders (OCDs) among the healthcare workers (HCWs) to compare in COVID positive services with control group. This cross-sectional study was conducted on 198 subjects participating study. test difference between two groups involved COVID-19 hospitalization section normal Anxiety, Depression, Scale, sample independent t-tests, however, Welch–Satterthwaite P Values were considered for significance. The categorical variables (sex,...

Objective:In this study, to evaluate the clinical course and prognosis in COVID-19 patients, hematological biochemical parameters at time of admission hospital.
 Methods:This retrospective study was performed a multicenter April October 2020. Demographic characteristics, features, age, gender length stay patients who exitus (EX) were discharged due examined.
 Results:Of (n:180) included 89 female 91 male. There significant difference between from hospital died complaints (p0.05)....

Objective: As the coronavirus disease 2019 (COVID-19) pandemic continues, clinical and laboratory predictors of progression to serious lethal types illness are urgently needed. We aimed investigate how well hematologic, biochemical, immunologic biomarkers could distinguish between patients with without severe or fatal COVID-19. Material Methods: This retrospective study was performed in internal medicine departments two institutions. Data were collected from hospital database, medical files...

Objective: Covid-19 may cause thrombosis in both venous and arterial systems. Familiarity with the signs symptoms of their treatment plays an important role treating infection its complications. D-Dimer Mean platelet volume (MPV) are measurements related to development thrombosis. This study investigates whether MPV values could be used determine risk mortality early stages. Methods: 424 patients were randomly retrospectively included study, Covid 19 positive according World Health...

Background: There is an urgent need for mortality predictors COVID-19 so that clinicians can diagnose severe cases and triage them as soon possible. Many studies have suggested using hematologic markers to predict severity of disease. This study investigates the use monocyte-to-high density lipoprotein cholesterol ratio (MHR) a predictive marker mortality. Methods: retrospective cross-sectional was performed on 81 PCR-confirmed patients between 25 March 2020 26 June 2020. Patients were...

Aim: The aim of this study is to investigate relationship between immunoglobin (Ig) levels and severity COVID-19 disease.Material Methods: was carried out at Ayancık State Hospital.Ethics committee approval obtained before starting the study.Patients who applied Hospital 2021-2022 were diagnosed with over age 19 included in study.Data on demographic laboratory parameters patients from hospital information system records.Patient files additional not study.Demographic data, immunoglobulin...

Objective: It is known that Thyroid Ultrasonography (US), guided by Fine Needle Aspiration (FNA), a cost-effective and safe diagnostic method for evaluating thyroid nodules. Our purpose in the present study to determine reliability of Imaging Reporting Data Systems (TIRADS) Scoring System evaluation Materials Methods: A total 3612 patients who were followed up our endocrinology general surgery clinic operated on with diagnosis multinodular nodular goiter included study. The malignancy risk...

Objective:The risk of gallstones is increased in fatty liver, overweight, and metabolic syndrome.The hyperinsulinemiceuglycemic clamp method considered the best for insulin resistance (IR); but it a time consuming expensive procedure.As an alternative strategy, this study, we would like to demonstrate triglyceride-glucose (TyG) index as predictor development gallstone disease associated with disorders. Methods:The TyG was investigated our study 1484 patients between ages 18-75 who underwent...

Aim: This study was planned to compare perioperative 5-Fluorouracil (5-FU), oxaliplatin and docetaxel (FLOT) chemotherapy regimens with postoperative adjuvant oral capecitabine oxaliplatin/5-FU (CAPEOX/FOLFOX) regimens. Material Method: single-center, retrospective recruited 59 subjects (17 females 42 males) at least T2 or more invasive gastric cancers without positive lymph node(s). All the patients underwent total subtotal ((sub) total) resection D2 node dissection. The Statistical Package...

Amaç: Bu çalışmada amaç iç göçün Tüberküloz (TB) epidemiyolojisine etkisini incelemek ve TB hastalarının sosyodemografik özelliklerini, tanı tedavi süreçlerini değerlendirmektir. Gereç Yöntem: Çalışma Yalova Eğitim Araştırma Hastanesi (YEAH)’nde yürütüldü. Çalışmaya başlamadan önce gerekli kurum izinleri alındı. 2022-2024 arasında takip edilen hastalarına ait veriler, hastane otomasyon sistemi üzerinden retrospektif olarak incelendi. Elde veriler SPSS 22 programında analiz edildi. Bulgular:...

Objective: The purpose of the research is to evaluate antibiotic consumption in hospitalized patients with a single-day point prevalence study. Methods: study was conducted at Yalova Training and Research Hospital (YEAH) on April 12, 2023. day, all clinics intensive care units were visited, information about sociodemographic data antibiotics used recorded form. resulting box-based analyzed SPSS program Defined Daily Dose (DDD) unit World Health Organization. Results: 150 included research,...

Objective: This study aims to examine the relationship between serum vitamin D levels and hematological parameters, body mass index. Material Methods: It was carried out in internal medicine outpatient clinic of Ayancık State Hospital April 2017 November 2020. Information about sociodemographic laboratory values patients obtained from hospital information system. The were divided into two groups as those with below 20 ng/ml over 30 ng/ml. Vitamin parameters all examined. Results: Of 343...