A5065251701- Colorectal Cancer Treatments and Studies
- Cancer Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Renal cell carcinoma treatment
- Inflammatory Biomarkers in Disease Prognosis
- Chronic Lymphocytic Leukemia Research
- Nausea and vomiting management
- Advanced Breast Cancer Therapies
- Cancer Treatment and Pharmacology
- Lung Cancer Research Studies
- Genetic factors in colorectal cancer
- Lung Cancer Treatments and Mutations
- HER2/EGFR in Cancer Research
- Radiomics and Machine Learning in Medical Imaging
- Cancer Genomics and Diagnostics
- Sarcoma Diagnosis and Treatment
- Multiple and Secondary Primary Cancers
- Cancer, Lipids, and Metabolism
- Hepatocellular Carcinoma Treatment and Prognosis
- Cancer Immunotherapy and Biomarkers
- Glioma Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Peptidase Inhibition and Analysis
- Cardiac tumors and thrombi
Necmettin Erbakan University
2019-2025
Afyon Kocatepe University
2017-2024
Afyonkarahisar Sağlık Bilimleri Üniversitesi
2024
Antalya IVF
2024
Ankara University
2023
Sağlık Bilimleri Üniversitesi
2019-2022
University Research Co (United States)
2022
Bridge University
2022
Ege University
2022
Malatya Devlet Hastanesi
2015-2016
A prospective, randomised and single blind clinical trial was designed to compare intravenous methylprednisolone pulse (IVGC) with oral (OGC) monotherapy in terms of effectiveness tolerability Graves' ophthalmopathy (GO). Fifty-two consecutive patients untreated, moderately severe active GO were randomly treated either IVGC or OGC therapy for 12 weeks. achieved a more rapid significant improvement than according activity score (p < 0.01), proptosis 0.038), lid width 0.0001), extraocular...
This study was conducted for the purpose of adapting Functional Assessment Chronic Illness Therapy-Spiritual Well-Being Scale (FACIT-Sp) Turkish context and determining its validity reliability.In 2016, a convenience sample 137 cancer patients from Malatya State Hospital completed structured questionnaire, which provided demographic characteristics, FACIT-Sp-12 with cancer. The obtained data were assessed using Cronbach's alpha reliability coefficient (α), Pearson's product-moment...
Background and Objectives: Malignant pleural mesothelioma (MPM) is a rare aggressive malignancy with poor prognosis. Identifying reliable prognostic factors crucial for risk stratification optimizing treatment strategies. This study aimed to evaluate the impact of clinicopathologic systemic inflammatory markers on survival outcomes in patients MPM. Materials Methods: retrospective, multicenter included 217 diagnosed MPM between January 2009 March 2024. Data age, gender, histology, disease...
The cysteine-rich epidermal growth factor ligand domain 2 protein (CRELD2) is associated with pathways that regulate epithelial-to-mesenchymal transition, a critical process driving cancer metastasis. This study aimed to determine the prognostic value of CRELD2 status on survival outcomes in triple-negative breast (TNBC). Seventy patients were included study. Thirty-four metastatic, and 36 non-metastatic. expression tumor tissue was determined by immunohistochemical (IHC) staining. divided...
ABSTRACT Objective The Prognostic Nutritional Index (PNI), reflects the nutritional and immunological status of patient has been associated with outcomes in various cancers. In this study, prognostic significance PNI metastatic hormone‐sensitive prostate cancer (mHSPC) its potential role guiding treatment decisions between abiraterone acetate enzalutamide is investigated. Methods Retrospective analysis was performed on 167 mHSPC patients treated 2019 2024. calculated using formula: 10 ×...
<title>Abstract</title> <bold>Aim:</bold> Immunotherapy has brought a new perspective to cancer treatments. However, the response of patients novel drug is heterogeneous. It essential reveal factors that may affect outcomes. was aimed evaluate effect antibiotherapy (Abx) on overall survival (OS) and progression-free (PFS) in with metastatic renal cell carcinoma (mRCC) receiving second-line nivolumab treatment. <bold>Method:</bold> The study multicentre, retrospective, multicentre design...
Despite numerous studies on second-line therapies in metastatic pancreatic cancer, there is no randomized study evaluating the efficacy of gemcitabine plus nab-paclitaxel as a treatment. This aims to examine therapy. In this retrospective study, total 218 patients from 23 centers were included. The primary endpoint was progression-free survival (PFS), secondary endpoints included overall (OS), treatment based ECOG performance status (PS), and tumor marker (CEA, CA 19 - 9) levels. with...
Introduction Cyclin-dependent kinase (CDK) 4/6 inhibitors have shown a different adverse effect. In this case, persistent grade 3 hepatoxicity was observed after ribociclib. Therefore, ribociclib therapy stopped, and then palbociclib introduced. Transaminase levels returned to normal by switching therapy. Case report 71-year-old postmenopausal female patient with luminal subtypes of metastatic breast cancer treated Management & outcome Grade hepatotoxicity secondary developed. She...
It is red cell distribution width (RDW) that has been reported to show an inflammatory response which studied recently. The aim of this study investigate whether the pre-treatment RDW in patients using first-line vascular endothelial growth factor tyrosine kinase inhibitor (VEGFR TKI) with diagnosis metastatic renal carcinoma (mRCC) predicts treatment and a prognostic or not.About 92 diagnosed mRCC who were being treated sunitinib pazopanib first line between January 2015 June 2021 included...
e20609 Background: Invasive mucinous adenocarcinoma (IMA) is a relatively rare histological subtype of lung adenocarcinomas that differs in its clinical behavior, radiologic features, histopathological, and genomic characteristics than invasive non-mucinous (INMA). Methods: We retrospectively investigated medical records patients diagnosed with IMA at four oncology centers Turkey. Patients who were ≥18 years age, pathologically IMA, received least one course treatment for metastatic or...
Bloom syndrome (BS) is a rare autosomal recessive disorder caused by loss-of-function mutation in the BLM gene encoding an RecQ helicase involved DNA repair and maintenance of chromosomal stability. In patients with BS, significant sensitivity to both DNA-damaging chemotherapy (CT) ionizing radiation complicates management neoplasms exacerbating comorbidities predisposing toxicities poor outcomes.
e13010 Background: The standard of care in patients with hormone receptor (HR) -positive metastatic breast cancer is a cyclin-dependent kinase (CDK) 4/6 inhibitor combined endocrine therapy (ET). Preclinical studies show that metabolic processes and cell metabolism such as adipogenesis, lipid synthesis glucose regulation affected by cycle regulators CDK 4 6. There are limited data regarding the impact body mass index (BMI) on efficacy inhibitors plus (ET) cancer. We aimed to investigate...
Abstract Background The adverse effects of COVID-19 pandemic on the mental health high-risk group patients for morbidity and mortality its impact public in long term have not been clearly determined. Objective To determine level related transmission fear anxiety healthcare workers with primary immunodeficiency disorder (PID), severe asthma, ones other comorbidities. Methods PID, asthma (all receiving biological agent treatment), malignancy, cardiovascular disease, hypertension (90% ACEI or...