A5058377151- Autoimmune Bullous Skin Diseases
- Cancer and Skin Lesions
- Urticaria and Related Conditions
- Inflammatory Myopathies and Dermatomyositis
- Endometrial and Cervical Cancer Treatments
- Drug-Induced Adverse Reactions
- Skin Diseases and Diabetes
- Genital Health and Disease
- Peptidase Inhibition and Analysis
- Genetic factors in colorectal cancer
- Tendon Structure and Treatment
- Gastric Cancer Management and Outcomes
- Orthopedic Surgery and Rehabilitation
- Bone Tumor Diagnosis and Treatments
- Psoriasis: Treatment and Pathogenesis
- IgG4-Related and Inflammatory Diseases
- Gastrointestinal Tumor Research and Treatment
- Shoulder Injury and Treatment
- Cytomegalovirus and herpesvirus research
- Pancreatitis Pathology and Treatment
- Hernia repair and management
- Ubiquitin and proteasome pathways
- Sarcoma Diagnosis and Treatment
- Breast Lesions and Carcinomas
- Pediatric Urology and Nephrology Studies
Necmettin Erbakan University
2014-2025
European School of Oncology
2019
Selçuk University
2009-2010
Hacettepe University Hospital
1995
The clinical feature of breast cancer is very heterogeneous because the variable prognostic factors impact its behaviour. aim study to find importance Ki-67 and analyse correlation between index other conventional in patients.Between 2010 2017, patients with invasive ductal carcinoma who received radiotherapy after surgery were included study. A single pathologist re-defined all cases retrospectively. established three categories based on levels: low (<10%), intermediate (10-25%) high...
The cysteine-rich epidermal growth factor ligand domain 2 protein (CRELD2) is associated with pathways that regulate epithelial-to-mesenchymal transition, a critical process driving cancer metastasis. This study aimed to determine the prognostic value of CRELD2 status on survival outcomes in triple-negative breast (TNBC). Seventy patients were included study. Thirty-four metastatic, and 36 non-metastatic. expression tumor tissue was determined by immunohistochemical (IHC) staining. divided...
There is no marker that can predict whether there resistance to treatment in patients with psoriasis. In this study, we investigated the relationship between staining rates of TNF-α, IL-1, IL-12, IL-17, IL-23, and IL-36 markers immunohistochemically from cutaneous biopsy success.
In this study, we aimed to report long-term follow-up of our pediatric and adult patients with DCLRE1C (DNA cross-link repair 1C) hypomorphic mutation who were diagnosed leaky severe combined immunodeficiency (SCID).
To evaluate and compare the expression of thioredoxin reductase 1 (TrxR1) in primary secondary glioblastoma samples.Surgically resected human samples from 40 patients who underwent surgery at our institution were extracted their histopathological specimens divided into three groups. Ten histopathologically regular cerebral tissue samples, acquired non-neoplastic portion specimens, assigned as control group. Twenty that included tumoral each type (WHO grade IV, secondary) TrxR1 was analyzed...
Objective:The prognostic importance of extracapsular extension (ECE) in breast cancer is not yet clear, especially patients with pathological T1-2 and N1 (pT1-2N1) disease.We aimed to investigate whether the extent ECE was an independent factor for survival outcomes pT1-2N1 cancer. Materials Methods:A total number 131 treated between 2009 2015 were retrospectively evaluated.A single pathologist re-analyzed histologic examples all cases.The graded from 0 4. Results:There a significant...
Pseudolymphoma, also known as Jessner’s lymphocytic infiltration, is a benign but usually chronic, T-cell infiltrating disease with erythematous papules and plaques seen on the skin of face, neck, back. The use leech therapy hirudotherapy has increased in recent years. Here, we report 52-year-old male patient who had undergone his neck developed after four months. A biopsy confirmed diagnosis infiltration. In parallel increasing years, side-effect reports will likely to increase. Indications...
There are limited data about the cutaneous metastases of gynecological malignancies in literature. Based on this number studies, from uncommon occurrences. Cutaneous synchronous endometrioid carcinoma uterine corpus and bilateral ovaries arising endometriosis extremely rare. Herein, we report a 51-year-old woman with FIGO Stage 1A Grade 1 endometrial endometrioid-type adenocarcinoma 1B ovarian who presented 34 months following total abdominal hysterectomy salpingo-oophorectomy skin...
Objective: Discoid lupus erythematosus (DLE) is a chronic inflammatory skin disease that can be triggered by several factors although its etiology not yet known.Hypotheses have been reported the demodex mites may involved in etiopathogenesis of DLE.In this study, we aimed to investigate potential relationship between frequency immunohistochemical staining tumor necrosis factor (TNF)-α, interleukin (IL)-1, IL-12, IL-17 and IL-23 cytokines obtained from cutaneous biopsy DLE patients...
Objectives. This study aimed to determine histopathologic changes in the pelviureteral junction children with obstruction. Material and methods. Seventeen specimens obtained from were divided into two groups: obstruction (n = 7) control 10). Wall thickness of junction, tunica muscularis uroepithelium collagen evaluated resected junctions Main findings. The mean wall not significantly higher than those group. Collagen values group Conclusions. Our data suggest that (tunica uroepithelium) was...
Aim . We determined the effects of diclofenac sodium, octreotide, and their combination on extrapancreatic organ injuries in caerulein-induced acute pancreatitis mice. Methods A total 58 BALB-C male mice (25 g) were divided into seven groups used to create a model. Diclofenac given for treatment caerulin-induced At end experiment, lung, liver, kidney, stomach removed histopathologic assessment. Results Histopathologic investigation revealed statistically significant difference between mean...
The objective of this study was to investigate the effects that application mesenchymal stem cells (MSCs) and platelet rich plasma (PRP) following tendon repair has on strength healing also examine possible mechanisms action take place.The Achilles tendons 80 rats were repaired divided into eight groups. Following repairs, MSCs obtained from humans injected rat in groups 1 2, a combination PRP 3 4, 5 6. These procedures all took place simultaneously. Groups 7 8 did not receive any injections...
Background: The aim of this study was to investigate the antifibrinolytic and anti-inflammatory effects hesperidin, tenoxicam enoxaparin on intrapleural adhesions in an experimental rat model. Methods: A total 52 healthy adult male Wistar Albino rats from same colony were randomly divided into six groups as sham (Group 1), surgical control 2), low-dose hesperidin 3), high-dose 4), 5), 6). All subjects underwent left thoracotomy except for group, adhesion model applied and, postoperatively,...
Cardiac myxoma and papillary fibroelastoma are the most common benign primary cardiac tumors in adults. In this brief report, we described a male patient with mass tricuspid valve (papillary as result of pathology), who presented thrombocytopenia underwent replacement. The was followed treated by hematology clinic due to thrombocytopenia, but definitive diagnosis could not be made. incidentally diagnosed while being investigated for urinary stones. Thrombocytopenia improved postoperative...