Fatih Keskin

ORCID: 0000-0003-3569-0307
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About
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Research Areas
  • Pregnancy and preeclampsia studies
  • Reproductive System and Pregnancy
  • Pregnancy and Medication Impact
  • Inflammatory Biomarkers in Disease Prognosis
  • Spine and Intervertebral Disc Pathology
  • Cardiac Ischemia and Reperfusion
  • Endometriosis Research and Treatment
  • Obstructive Sleep Apnea Research
  • Orthopedic Surgery and Rehabilitation
  • Electrolyte and hormonal disorders
  • Vitamin D Research Studies
  • Vaccine Coverage and Hesitancy
  • Neonatal Respiratory Health Research
  • Pharmacological Effects and Toxicity Studies
  • Neuroscience of respiration and sleep
  • Tryptophan and brain disorders
  • Maternal and fetal healthcare
  • Ectopic Pregnancy Diagnosis and Management
  • Reproductive Health and Contraception
  • Infectious Aortic and Vascular Conditions
  • Gynecological conditions and treatments
  • Caveolin-1 and cellular processes
  • Preterm Birth and Chorioamnionitis
  • Spinal Cord Injury Research
  • Antibiotics Pharmacokinetics and Efficacy

Helios Klinikum Krefeld
2022

Ankara (Czechia)
2021

Necmettin Erbakan University
2014-2020

State Hospital
2019

Sivas State Hospital
2018

Düzce Üniversitesi
2013-2015

Konya Eğitim ve Araştırma Hastanesi
2015

Sağlık Bilimleri Üniversitesi
2010

St. Josef-Hospital
2004-2005

Ruhr University Bochum
2004

Recent studies suggest an association of obstructive sleep apnoea (OSA) with cardiovascular risk factors, such as dyslipidaemia. The present study analyses the effects OSA and its therapy on serum lipid concentrations in 470 patients a single centre study. Multivariate regression showed significant between apnoea–hypopnoea index high-density lipoprotein cholesterol (HDL-C) levels (n = 366), independent age, sex, body mass index, diabetes lowering medication. There were no associations total...

10.1183/09031936.06.00131304 article EN European Respiratory Journal 2005-12-30

Background:There is increasing evidence that obstructive sleep apnea an independent risk factor for arterial hypertension. Previous studies on the antihypertensive effects of positive airway pressure therapy daytime blood (BP) revealed inconsistent results.

10.1016/j.amjhyper.2004.06.026 article EN American Journal of Hypertension 2004-12-01

Missed abortion occurs in ∼ 15% of all clinical pregnancies. The pathogenesis is not clearly known. However, defective placentation resulting maternal systemic inflammatory response considered responsible for missed abortion. Platelet lymphocyte ratio (PLR) and neutrophil (NLR) are increasingly cited parameters inflammation the literature. no study evaluated PLR NLR rates abortions so far. aim present to investigate whether complete blood count (CBC) such as increased patients with Medical...

10.1055/s-0040-1709693 article EN cc-by Revista Brasileira Ginecologia e Obstetrícia 2020-05-01

Vitamin D deficiency is a frequent finding in schizophrenia and may contribute to neurocognitive dysfunction, core element of the disease. However, there limited knowledge about neuropsychological profile vitamin deficiency-related cognitive deficits their underlying molecular mechanisms. As an inductor cytochrome P450 3A4, lack might aggravate by increased exposure anticholinergic antipsychotics. This cross-sectional study aims assess relationship between 25-OH-vitamin D-serum...

10.3390/biomedicines10051096 article EN cc-by Biomedicines 2022-05-09

Aims Patients with schizophrenia frequently show insufficient vitamin D levels, which are associated somatic comorbidity and may contribute to psychopathology. For many reasons, supplementation be indicated for this patient cohort. However, there is growing evidence a D‐mediated increase of drug metabolism by induction cytochrome P450 (CYP) 3A4. Hence, study aimed assess D's impact on both antipsychotic concentrations psychopathology in non‐interventional manner. Methods Totals 107 serum...

10.1111/bcp.15223 article EN cc-by-nc British Journal of Clinical Pharmacology 2022-01-10

In the recent years, traffic incidents sharply increase in Turkey. Although regulations strictly applied Middle East Technical University Campus (METU), Ankara, Turkey, this increasing trend also present campus. To prevent incidents, it is crucial to understand where and how they take place, relations among locations. The aim of study make a pattern analysis concerning time locations within METU using spatial data tools. aims at answering whether there are any which show clustering...

10.1016/j.sbspro.2011.05.108 article EN Procedia - Social and Behavioral Sciences 2011-01-01

To evaluate and compare the expression of thioredoxin reductase 1 (TrxR1) in primary secondary glioblastoma samples.Surgically resected human samples from 40 patients who underwent surgery at our institution were extracted their histopathological specimens divided into three groups. Ten histopathologically regular cerebral tissue samples, acquired non-neoplastic portion specimens, assigned as control group. Twenty that included tumoral each type (WHO grade IV, secondary) TrxR1 was analyzed...

10.5137/1019-5149.jtn.18991-16.2 article EN Turkish Neurosurgery 2017-01-01

AIM: Epidural fibrosis is an important factor for postoperative failed back syndrome development and causes clinical complaints in 6-25% of cases.An effective treatment modality has not been found yet.The aim this study to investigate the anti-adhesive effects a novel agent chitin compare these with popular adhesion barrier collagen matrix.MATeRIAL MeTHodS: 21 rabbits were allocated into three groups including 7 each.L5 total laminectomy was performed all groups.No given Group 1 (Control...

10.5137/1019-5149.jtn.3205-10.2 article EN Turkish Neurosurgery 2010-01-01

Background: Recurrent miscarriage (RM) is a frequent obstetric problem. Its’ pathophysiology poorly understood. Infections, genetic, endocrine, anatomic and immunologic problems have been suggested as causes for RM. Objective: To evaluate the frequency of chromosomal abnormalities 3 common thrombophilic mutations in couples with Methods: A retrospective data collection was performed results cytogenetic analysis Methylenetetrahydrofolate Reductase (MTHFR) C677T, Factor V Leiden (FVL) G1691A...

10.4314/ahs.v14i1.34 article EN cc-by African Health Sciences 2014-03-11

The sacral canal has been frequently used as "a passage" for minimally invasive diagnostic and therapeutic procedures spinal diseases. aim of the present study was to investigate morphometric analyses canal, hiatus, surrounding structures according different age groups gender by using "multidetector computed tomography" method.Multiplanar-reconstructed images from 300 adult (150 females 150 males, between 20 80 years old) were divided into three retrospectively examined. Various anatomic...

10.5137/1019-5149.jtn.10942-14.0 article EN Turkish Neurosurgery 2014-01-01

Background and Objective. It is unclear how immune tolerance develops to a semiallograft fetus in pregnancy. Human leukocyte antigen G (HLA-G) expressed by extravascular trophoblasts plays an important role the recognition of gestational tissues as self development against maternal system. The soluble form HLA-G (sHLA-G) molecule serum also reported contribute prevention rejection during aim study was compare sHLA-G levels women with missed abortions control subjects uncomplicated...

10.3390/medicina49100068 article EN cc-by Medicina 2013-11-04

Abstract Placenta accreta syndromes are associated with increased maternal mortality and morbidity. Cesarean hysterectomy is usually performed in cases of placenta syndrome. Fertility sparing methods can be applied. In the present study, we report a successful segmental uterine resection method for anterior wall cesarean section case. A 39-year-old woman underwent an elective at 38 + 2 weeks. placental tissue area 10 cm was observed extending from to serosa, above incision line. The removed...

10.1055/s-0038-1668528 article EN cc-by Revista Brasileira Ginecologia e Obstetrícia 2018-08-01

<b><i>Background/Aims:</i></b> Recent investigations in both males and females show that there may also be some genetic risk factors associated with infertility, endothelial nitric oxide synthase (eNOS) has important functions implantation. We aimed to investigate the association of three different polymorphisms eNOS (promoter -786T/C, exon 894 G/T intron G10T) unexplained female infertility. <b><i>Materials Methods:</i></b> Two groups patients...

10.1159/000357442 article EN Gynecologic and Obstetric Investigation 2014-01-01

Aim: The incidence of missed abortion is around 15% clinically diagnosed pregnancies, and the etiology uncertain. Limited studies in literature report increased platelet indices such as mean volume (MPV), distribution width (PDW), plateletcrit (PCT). number cases these low results are inconsistent. There no study that investigates all indices. This has largest series abortion. Methods: In this retrospective case-control study, complete blood count parameters patients who were with examined....

10.28982/josam.530098 article EN Journal of Surgery and Medicine 2019-08-06

Pendrin is an integral membrane protein and plays a key role in extracellular fluid volume blood pressure control. We aimed to investigate the relationship between pendrin immunostaining intensity normal pre-eclamptic placental tissue.Fifty-six tissues, of which 26 were pre-eclamptic, 30 control group evaluated by immunohistochemical staining. Positive was using semiquantitative score: 0, negative; +, mild; ++, moderate; +++, intense.There more positive immunstaining placenta compared...

10.3109/14767058.2013.833600 article EN The Journal of Maternal-Fetal & Neonatal Medicine 2013-08-14

OBJECTIVE: To determine the effect of lemon-flavored lollipop on nausea and vomiting pregnancy.STUDY DESIGN: This prospective case-control study included 67 first trimester pregnant women. The 12-hour Pregnancy-Unique Quantification Emesis Nausea score was calculated at time presentation to hospital. group (32 cases) given lollipops while control (35 did not receive lollipops. scores patients were recalculated morning post-treatment day.RESULTS: higher (p=0.013) than in day admission....

10.21613/gorm.2019.973 article EN cc-by Gynecology Obstetrics and Reproductive Medicine 2019-10-07

OBJECTIVES: Online education and certification programs which help most gynecologic surgeons to advance, improve prove their skills. However, the benefits of such distant in terms complication rate operation time has not been evaluated so far. The aim this study was report improvement a single surgeon’s learning curve total laparoscopic hysterectomy who had no previous mentorship/fellowship education, working rural district hospital before after completion on-line program - Gynaecological...

10.21613/gorm.2019.1003 article EN cc-by Gynecology Obstetrics and Reproductive Medicine 2019-10-25

Spinal cord injury effects social and economical life negatively with its high mortalitiy morbidity. Paraplegia which occurs due to spinal ischemia, during thoracic thorocoabdominal aorta surgery is still a serious complication. In this study, we investigate the possible neuroprotective of strong antioxidant, free radical scavenger; octreotide acetate on rabbit ischemia/reperfusion (I/R) model. A total 18 rabbits were divided into 3 groups 6 each, as follows: group 1 (n=6) sham, laparotomy...

10.1097/wnq.0000000000000109 article EN Neurosurgery Quarterly 2014-07-10

Unexpected pregnancy with an intrauterine device (IUD) in situ is not uncommon finding daily practice.It generally agreed that IUD should be removed the first trimester when its tail visible vaginally.However, because of limited experience and data literature, uncertainty exists about management technique removal during tails are inaccessible on examination, especially second trimester.The may left or using a grasping tool under ultrasonographic guidance by hysteroscopy.Here, we report case...

10.4293/crsls.2013.00062 article EN CRSLS Journal of the Society of Laparoscopic and Robotic Surgeons 2015-03-27

Objective: Preterm deliveries increased in many countries recent years.However, despite fetal lung maturity, substantial neonatal morbidity may occur even after 34 weeks of gestation.The aim this study was to evaluate and mortality women with late preterm births.Design: Retrospective.

10.5505/tjod.2013.18942 article EN Journal of Turkish Society of Obstetric and Gynecology 2013-01-01
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