N. S. Turhal

ORCID: 0000-0002-1013-5676
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About
Contact & Profiles
Research Areas
  • Colorectal Cancer Treatments and Studies
  • Lung Cancer Treatments and Mutations
  • Gastric Cancer Management and Outcomes
  • Lung Cancer Diagnosis and Treatment
  • Cancer Treatment and Pharmacology
  • Lung Cancer Research Studies
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Colorectal and Anal Carcinomas
  • Breast Cancer Treatment Studies
  • HER2/EGFR in Cancer Research
  • Colorectal Cancer Surgical Treatments
  • Advances in Oncology and Radiotherapy
  • Cancer survivorship and care
  • Peptidase Inhibition and Analysis
  • Cancer Diagnosis and Treatment
  • Renal cell carcinoma treatment
  • Cancer Risks and Factors
  • Palliative Care and End-of-Life Issues
  • Economic and Financial Impacts of Cancer
  • Advanced Breast Cancer Therapies
  • Colorectal Cancer Screening and Detection
  • Metastasis and carcinoma case studies
  • Neuroendocrine Tumor Research Advances
  • Cancer-related Molecular Pathways
  • Cancer, Lipids, and Metabolism

Anadolu University
2016-2024

AstraZeneca (Brazil)
2024

Weatherford College
2024

Pfizer (United States)
2024

Pfizer (United Kingdom)
2024

Roche (Switzerland)
2024

Novartis (Switzerland)
2024

Turkish Society of Hematology
2023

Health Center
2022

John Wiley & Sons (United States)
2021

Serum leptin level is associated with appetite and energy expenditure in healthy individuals. We aimed to evaluate the serum concentration other factors which may be weight loss patients advanced gastrointestinal cancer.Forty-four cancer (25 gastric 19 colorectal cancer) 25 controls were enrolled. levels measured as ng/ml via enzyme linked immuno-sorbent assay (ELISA) method all subjects. The difference between control group, factor its relationship was evaluated.Serum of group significantly...

10.1186/1471-2407-4-29 article EN cc-by BMC Cancer 2004-06-24

Ribociclib, palbociclib and abemaciclib are currently approved CDK4/6 inhibitors along with aromatase as the first-line standard-of-care for patients hormone receptor-positive, HER2-negative metastatic breast cancer.

10.2217/fon-2022-1287 article EN Future Oncology 2023-03-01

The long-term use of subcutaneous implanted ports for chemotherapy in cancer patients has been associated with the occurrence thrombosis and infection. In this study, we compared safety efficacy administration 1000 U heparin flushes prolonged interval (every 6 weeks) standard dose schedule (500 every 4 port-related infections during periods non-use. Data were collected retrospectively from treated various types (matched as 2:1 age, gender, stage disease). Patients who had diseases that could...

10.1111/j.1365-2354.2008.00973.x article EN European Journal of Cancer Care 2009-02-25

Metastatic castration-resistant prostate cancer (mCRPC) remains a challenging condition to treat despite recent advancements. This retrospective study aimed assess the activity and tolerability of Lutetium-177 (Lu-177) PSMA-617 radioligand therapy (RLT) in mCRPC patients across multiple centers Turkey. The included 165 who received at least one cycle Lu-177 RLT, with majority having bone metastases undergone prior treatments. Prostate-specific antigen (PSA) levels were assessed before each...

10.1002/ijc.34749 article EN International Journal of Cancer 2023-10-11

Background: Breast cancer is the most common in women. Primary treatment surgery, with breast conserving surgery (BCS) being widely used for early-stage disease. Due to changes body image, depressive symptoms can occur after surgery. Here, we evaluate factors that affect patients' decision on and investigate differences level of depression mastectomy or BCS a population Turkish patients. Patients Methods: One hundred patients who had undergone were followed up at our institution between 2007...

10.1159/000314266 article EN Breast Care 2010-01-01

This study aimed to determine the epidemiological characteristics of colorectal cancer in Turkey.In this multicenter, prospective, and cross-sectional registry study, data for 968 patients with from 21 centers 7 geographic regions were analyzed.Diagnosis was colon 662 (68.4%) rectum 306 (31.6%) patients. In total, 60.9% male; mean age 58.9±12.6 years. Among patients, 15.0% drinking alcohol, 17.5% smoking, 1.5% had familial history polyposis, diabetes mellitus, 1.0% inflammatory bowel...

10.5152/tjg.2015.5685 article EN The Turkish Journal of Gastroenterology 2015-03-13

<i>Background:</i> Angiogenesis is one of the key steps in solid tumor growth and metastasis. We planned to investigate prognostic significance vascular endothelial factor (VEGF), hypoxia-inducible 1α (HIF-1α) CD34 expressions as markers angiogenesis gastric cancer. <i>Patients Methods:</i> retrospectively reviewed medical records 51 cancer patients who had total or subtotal gastrectomy at Marmara University Hospital from 1990 2004 evaluated expression VEGF, HIF-1α by...

10.1159/000111118 article EN Oncology 2007-01-01

Abstract Background The optimal treatment for metastatic colorectal cancer (mCRC) after the second line is still controversial. Regorafenib has been standard of care in this setting as it improved overall survival (OS) compared to placebo. In real-world practice chemotherapy rechallenge also a preferred option even though supporting evidence not enough. We aim compare efficacy regorafenib and 5-fluorouracil-based (5-FU) third mCRC. Methods retrospective multi-institutional trial, mCRC...

10.1186/s12885-023-11783-5 article EN cc-by BMC Cancer 2024-01-02

To determine and evaluate the pharmaceutical care needs quality of life patients with colorectal cancer.36 Patients cancer eligible for chemotherapy after surgery were included in study. The followed up during 3 courses individual plans developed. was evaluated before third course chemotherapy.The incidence drug-related problems (DRPs) chemotherapy-treated reduced 3rd as compared 1st (63.9% vs 75%, respectively; n=36; p>0.05). clinical oncology pharmacist gave 147 recommendations to...

10.1136/ejhpharm-2016-001188 article EN European Journal of Hospital Pharmacy 2017-03-10

We present demographic, clinical, laboratory characteristics and outcomes of the patients with solid malignancies novel coronavirus disease (COVID-19) collected from National COVID-19 Registry Turkey. A total 1523 a current or past diagnosis tumors diagnosed (confirmed PCR) between 11 March 20 May 2020 were included. The primary outcome was 30-day mortality. Median age 61 (range: 18-94), 752 (49%) male. most common types cancers breast (19.8%), prostate (10.9%) colorectal cancer (10.8%). 65%...

10.1002/ijc.33426 article EN International Journal of Cancer 2020-12-07

A high-risk group of patients with stage II colon cancer has been identified by the results studies in Western populations. The aim this study was to investigate prognostic factors adjuvant chemotherapy Turkish cancer.A total 554 were retrospectively enrolled study. Three hundred fifty-three had received (5-FU-LV, FOLFOX or FLOX) and 201 no chemotherapy. T4 tumor stage, lymphovascular invasion, perineural bowel obstruction and/or perforation, <12 harvested lymph nodes, poor differentiation...

10.1177/030089161410000205 article EN Tumori Journal 2014-03-01

Hepatocellular carcinoma (HCC) is the fifth most common male-predominant type of cancer worldwide. There no effective treatment regimen available for advanced‑stage disease and chemotherapy generally ineffective in these patients. The number studies on prevalence K‑Ras mutations HCC patients currently limited. A total 58 from 6 comprehensive centers 4 metropolitan cities Turkey were enrolled this study. Each center committed to enroll approximately 10 random whose formalin‑fixed...

10.3892/mco.2015.633 article EN Molecular and Clinical Oncology 2015-08-31

A high-risk group of patients with stage II colon cancer has been identified by the results studies in Western populations. The aim this study was to investigate prognostic factors adjuvant chemotherapy Turkish cancer.A total 554 were retrospectively enrolled study. Three hundred fifty-three had received (5-FU-LV, FOLFOX or FLOX) and 201 no chemotherapy. T4 tumor stage, lymphovascular invasion, perineural bowel obstruction and/or perforation, <12 harvested lymph nodes, poor differentiation...

10.1700/1491.16397 article EN Tumori Journal 2014-05-24

Hepatocellular carcinoma (HCC) is a significant health problem, and the associated mortality rate increasing.We aimed to determine clinical characteristics prognosis for HCC in member countries of OncoBridge Study Group.We recruited 630 patients diagnosed with between 2013 2019 from 4 (Türkiye, Russia, Georgia, Greece). Univariate multivariate analyses were conducted investigate laboratory prognostic factors. Receiver operating characteristic (ROC) analysis was used value neutrophil...

10.26719/emhj.23.087 article FR Eastern Mediterranean Health Journal 2023-06-27
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