Alpaslan Mayadağlı

ORCID: 0000-0003-3463-563X
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Research Areas
  • Lung Cancer Treatments and Mutations
  • Gastric Cancer Management and Outcomes
  • Brain Metastases and Treatment
  • Advanced Radiotherapy Techniques
  • Lung Cancer Diagnosis and Treatment
  • Lung Cancer Research Studies
  • Management of metastatic bone disease
  • Neuroendocrine Tumor Research Advances
  • Metastasis and carcinoma case studies
  • Cancer Diagnosis and Treatment
  • Colorectal Cancer Treatments and Studies
  • Head and Neck Cancer Studies
  • Glioma Diagnosis and Treatment
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Cancer and Skin Lesions
  • Colorectal and Anal Carcinomas
  • Medical Imaging and Pathology Studies
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Peptidase Inhibition and Analysis
  • Effects of Radiation Exposure
  • Cancer survivorship and care
  • Meningioma and schwannoma management
  • Dental Implant Techniques and Outcomes
  • Pancreatic and Hepatic Oncology Research
  • Endometrial and Cervical Cancer Treatments

Bezmiâlem Vakıf Üniversitesi
2014-2024

Ankara Onkoloji Eğitim ve Araştırma Hastanesi
2011-2021

Foundation University
2018

Dr Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi
2005-2014

İstanbul Eğitim ve Araştırma Hastanesi
2011-2014

Sivas State Hospital
2012

CyberOptics (United States)
2012

Ministry of Health
2011

Haydarpaşa Numune Eğitim ve Araştırma Hastanesi
2007

Marmara University
2006

The present study was undertaken to determine whether resveratrol (RVT) could ameliorate ionizing radiation-induced oxidative injury. After a 10-days pre-treatment with RVT (10 mg/kg/day p.o.), rats were exposed whole-body IR (800 cGy) and the treatment continued for 10 more days after irradiation. Irradiation caused significant decrease in glutathione level, while malondialdehyde levels, myeloperoxidase activity collagen content increased liver ileum tissues. Similarly, plasma lactate...

10.1080/10715760903171100 article EN Free Radical Research 2009-01-01

Radiation-induced enteritis is a well-recognized sequel of therapeutic irradiation. Therefore we examined the radioprotective properties Punica granatum peel extract (PPE) on oxidative damage in ileum. Rats were exposed to single whole-body X-ray irradiation 800 cGy. Irradiated rats pretreated orally with saline or PPE (50 mg/kg/day) for 10 days before and following days, while control received but no Then plasma ileum samples obtained. Irradiation caused decrease glutathione total...

10.1269/jrr.08126 article EN cc-by-nc Journal of Radiation Research 2009-01-01

Background: Breast cancer is the most common in women. Primary treatment surgery, with breast conserving surgery (BCS) being widely used for early-stage disease. Due to changes body image, depressive symptoms can occur after surgery. Here, we evaluate factors that affect patients' decision on and investigate differences level of depression mastectomy or BCS a population Turkish patients. Patients Methods: One hundred patients who had undergone were followed up at our institution between 2007...

10.1159/000314266 article EN Breast Care 2010-01-01

Several clinical studies have shown that thrombocytosis is a poor prognostic factor in some types of cancer, but data about the impact on prognosis patients with colon cancer are very limited. We investigated prevalence and effect pre-operative thrombocytosis, defined as platelet count > 400 x 10(9)/l, retrospectively node-negative cancer. Out 198 patients, 24 (12.1%) had its presence correlated tumour depth lymphatic invasion. Univariate analysis revealed disease-free survival overall were...

10.1177/147323000503300211 article EN Journal of International Medical Research 2005-03-01

The aim of this study was to determine the prognostic value metastatic lymph node ratio (n ratio).We retrospectively analyzed 202 patients who had undergone curative gastrectomy. factors including UICC/AJCC TNM classification and n were evaluated by univariate multivariate analysis.The significantly higher in with gastric tumors undifferentiated histology, greater size, lymphatic vessel, blood vessel perineural invasion (PNI), advanced stage. Multivariate analysis indicated that pN...

10.1159/000277927 article EN Oncology Research and Treatment 2010-01-01

Background: Although a number of studies have investigated whether tumor diameter is prognostic factor in gastric cancer, no consensus was reached on its clinical importance. In this study, we aimed to determine the effect size survival patients with pT3 cancer. Patients and Methods: A total 232 who underwent curative gastrectomy D2 lymph node dissection, were retrospectively analyzed. Receiver operating characteristics analysis showed that cutoff value for 8 cm. On basis point, divided into...

10.1159/000322215 article EN Onkologie 2010-01-01

Anemia is a major cause of morbidity in patients with cancer resulting poor physical performance, prognosis and therapy outcome. The aim this study to assess the efficacy intravenous (iv) iron administration for correction anemia, prevention exacerbation decreasing blood transfusion rates, survival patients.Patients different solid tumor diagnosis who received iv during their treatment were evaluated retrospectively. Sixty-three hemoglobin (Hgb) levels between ≥ 9 g/dL, ≤ 10 no urgent need...

10.1186/s12885-016-2686-2 article EN cc-by BMC Cancer 2016-08-20

Abstract The goal of this study was to demonstrate the effect radiotherapy (RT) on nasal mucosa in rats and evaluate radioprotective effects topical application black seed oil ( Nigella sativa [NS]) treat acute radiation-induced mucositis. A total 18 were randomized into 3 groups, with 6 animals per group. group 1 topically administered saline cavity after sham irradiation. Group 2 received at same dose given NS groups irradiated a single 40 Gy paranasal area. Only one drop (0.05 mL) applied...

10.1097/scs.0000000000004314 article EN Journal of Craniofacial Surgery 2018-01-21

Locoregional recurrence is a major problem in esophageal cancer patients treated with definitive concomitant chemoradiotherapy. Approximately half of the fail locoregionally. We analyzed impact enlarged radiation field size and higher dose incorporated to chemoradiotherapy on oncologic outcome. Seventy-four consecutive histologically proven nonmetastatic squamous or adenocarcinoma esophagus were included this retrospective analysis. All locally advanced cT3–T4 and/or cN0-1. Treatment...

10.1186/s12957-016-1024-0 article EN cc-by World Journal of Surgical Oncology 2016-10-13

Metastases are the most common neoplasm in adult brain. In order to initiate treatment, an extensive diagnostic workup is usually required. Radiomics a discipline aimed at transforming visual data radiological images into reliable information. We examine capability of deep learning methods classify origin metastatic lesions brain MRIs and compare Convolutional Neural Network (CNN) with image texture based features.One hundred forty three patients 157 tumors were included study. The...

10.1002/jcu.23558 article EN Journal of Clinical Ultrasound 2023-09-09

Breast-conserving surgery (BCS) followed by radiotherapy (RT) is the standard treatment for early-stage breast cancer. The use of an additional RT dose (boost) to tumour bed improves local control but may worsen quality life (QOL) and cosmetic results. Multifocal/multicentric tumours (MMTs) pose a challenge as they require larger boost volumes. This study investigated impact volumes on late-term outcomes QOL in patients with unifocal MMTs who underwent adjuvant after BCS.Retrospective data...

10.4274/ejbh.galenos.2023.2023-5-4 article EN cc-by-nc-nd Meme sağlığı dergisi/Meme sağlığı dergisi 2023-09-28

As in all individuals, improving the quality of life, balanced nutrition and physical activity habits must be acquired cancer patients. The purpose this study was to determine eating patients receiving chemotherapy. Sixty-six were completed questionnaire included sociodemographic data, type cancer, anthropometric measurements (size body weight), dietary habits. Body mass index for each patient calculated. Data analyzed using Statistical Package Social Science software. Patients ranged from...

10.1080/01635581.2015.1053500 article EN Nutrition and Cancer 2015-07-02

AIM:To evaluate survival data in patients with gastric cancer relation to postoperative adjuvant therapy and determinants METHODS: A total of 201 (mean ± SD age: 56.0 11.9 years, 69.7% were males) carcinoma who operated followed up at Lutfi Kirdar Kartal Training Research Hospital between 1998 2010 included this retrospective study.Follow was evaluated divided into two consecutive periods (before 2008 2008-2010, respectively) based on introduction 3-D conformal technique radiotherapy our...

10.3748/wjg.v21.i4.1222 article EN cc-by-nc World Journal of Gastroenterology 2015-01-01

This study investigated the shear bond strength (SBS) of a universal adhesive to enamel/dentin; 1) that had undergone radiotherapy (RT) and 2) were readily restored RT. Enamel dentin surfaces obtained from 90 intact human molars. They randomly divided into six groups according presence timing irradiation (RT0:no radiotherapy/control, RT1:RT before restoration, RT2:RT after restoration groups) application modes (etch&rinse/ER, self-etch/SE)(n=15). A resin composites applied. The protocol...

10.15517/ijds.2022.50665 article EN Odovtos - International Journal of Dental Sciences 2022-04-01

<b><i>Background:</i></b> We investigated the role of standardized uptake values (SUVs) primary tumor in small cell lung cancer (SCLC) patients. <b><i>Patients and Methods:</i></b> The relationship between SUV response to treatment was using receiver operating characteristic (ROC) curve analysis, efficient cut-off value for detecting determined. effects on survival were investigated. <b><i>Results:</i></b> 90 patients...

10.1159/000444272 article EN Oncology Research and Treatment 2016-01-01

10.5505/jkartaltr.2011.82787 article EN The Journal of Kartal Training and Research Hospital 2011-01-01

We investigated the prevalence of anaemia (haemoglobin concentration < 12 g/dl) in 336 women with early-stage breast cancer and its association other known prognostic factors. The median follow-up period was 60.5 months (range 9 - 123 months). Seventy-nine (23.5%) had a low pre-treatment haemoglobin concentration, but not correlated age, tumour size, nodal status, histological grade or hormone receptor status. Univariate analysis revealed that disease-free survival overall were shorter...

10.1177/147323000503300307 article EN Journal of International Medical Research 2005-05-01

Amaç: Bu çalışmada, radyasyon onkolojisi bölümü çalışanlarının tükenmişlik ve depresyon düzeyleri ile bunlarla bağlantılı olabilecek sosyodemografik etkenler incelendi

10.5505/jkartaltr.2012.05025 article TR The Journal of Kartal Training and Research Hospital 2012-01-01
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