A5072642303- Gastric Cancer Management and Outcomes
- Gastrointestinal Tumor Research and Treatment
- Gastrointestinal disorders and treatments
- Pancreatic and Hepatic Oncology Research
- Sarcoma Diagnosis and Treatment
- HER2/EGFR in Cancer Research
- Glioma Diagnosis and Treatment
- Head and Neck Cancer Studies
- Thyroid Cancer Diagnosis and Treatment
- Colorectal Cancer Surgical Treatments
- Lung Cancer Treatments and Mutations
- Pancreatitis Pathology and Treatment
- Neuroendocrine Tumor Research Advances
- Thyroid Disorders and Treatments
- Inflammatory Bowel Disease
- Colorectal and Anal Carcinomas
- Oral and Maxillofacial Pathology
- Microscopic Colitis
- Mitochondrial Function and Pathology
- Ear and Head Tumors
- Cancer Cells and Metastasis
- Cutaneous Melanoma Detection and Management
- Cardiac tumors and thrombi
- Bone Tumor Diagnosis and Treatments
- Genetic factors in colorectal cancer
Gazi University
2014-2023
Fırat University
2020
Roche (United States)
2019
Ludwig-Maximilians-Universität München
2017
Kırıkkale University
2006
Abstract The effect of dysfunctional mitochondria in several cell pathologies has been reported renal diseases, including diabetic nephropathy and acute kidney injury. Previous studies have that mitochondrial transplantation provided surprising results myocardial liver ischemia, as well Parkinson's disease. We aimed to investigate the beneficial effects isolated from mesenchymal stem cells (MSCs) vivo, mitigate damage arises doxorubicin‐mediated nephrotoxicity its action mechanism. In this...
Adhesion formation after peritoneal surgery is a major cause of postoperative bowel obstruction, infertility, and chronic pelvic pain. In this study, we compared the possible individual effects phosphatidylcholine (PC), Seprafilm II, tissue plasminogen activator (t-PA) combined t-PA on adhesion in rat surgical model.
Human protothecosis is a rare microalgae infection, and its dissemination typically occurs in immunocompromised individuals, but no specific immune defect has been reported. Here, we describe an 8-year-old daughter of consanguineous union with abdominal pain bloody diarrhea for 3 months who was found to have pancolitis numerous identified as Prototheca zopfii. In the absence known immunodeficiency, exome sequencing performed, which uncovered novel recessive frameshift mutation CARD9...
CD133 is one of the most important stem cell markers in solid cancers and Ki-67 a marker that reflects proliferation. The relationships between expression prognosis gastric carcinoma are unknown need exploring. We examined 50 cancer patients retrospectively Radiation Oncology Department Faculty Medicine, Gazi University. was using immunohistochemical staining. survival rate with positive significantly worse than negative (p=0.04). Expression had correlation (r=0.350; p=0.014). Multivariate...
Determination of human epidermal growth factor receptor-2 status in advanced gastric cancer is important clinical decision making. In the trastuzumab for GC trial, trastuzumab-based therapy demonstrated a significant overall survival benefit patients with receptor-2-positive cancer. Human discordance primary and its metastases has been long debated. The aim study was to evaluate rate effect on treatment decisions A total 74 were included study. Both immunohistochemical staining dual-color...
In the present study, we aimed to evaluate possible effects of methylphenidate on rat testes. Forty-two Wistar rats were randomly distributed into three experimental groups 14 each. For 90 days, each group via gavage received following: 1 = tap water (control group), 2 5 mg/kg/day ritalin (methylphenidate, MPH), and 3 10 ritalin. After sacrificing animals, body weights as well absolute relative testicular measured. Testes sampled, fixed, processed and, by histopathological examination,...
ABSTRACT Objectives: There are many unknowns about primary eosinophilic gastrointestinal disease (EGID) in childhood. The aim of this study is to provide data the frequency, management, control level, and prognosis well documented EGID Methods: This was conducted children who underwent endoscopy and/or colonoscopy at a single center over 10‐year period up August 2018. Primary diagnosed after exclusion secondary classified as gastritis (EG), enteritis (EE), gastroenteritis (EGE: with...
Grading and staging are important in gastroenteropancreatic neuroendocrine tumors for directing treatment. In this study, we evaluated the histopathological parameters of statistically analyzed correlations these between World Health Organization (WHO) 2000 2010 classifications.A total 77 cases diagnosed as were included study. Cases classified according to WHO classification systems, differences two systems discussed.Among 50 that well-differentiated tumor 2000, 45 found be Grade 1 5 2...
The goals of the present study were to review our archives in order evaluate both diagnostic and prognostic ABSTRACTObjective: We aimed significance DOG1 on gastrointestinal stromal tumors (GISTs), add further insight about those issues current literature including some conflicting results.Material Method: was evaluated 100 cases GISTs, immunohistochemically.Immunostaining index counted for each antibody by using intensity extent staining.The association between immunostaining CD117, CD34,...
BACKGROUND:The aim of this study was to compare the clinical outcome in patients with pancreatic ductal adenocarcinoma who underwent frozen section and paraffin histology surgical resection margins during pancreaticoduodenectomy. MATERIAL AND METHODS:Frozen routine histopathology were performed using following categories: R0 (no tumor cells at margin), R1 (tumor at, or within 1 mm, R2 seen macroscopically margin). additional achieve R0. RESULTS:Of 346 pancreaticoduodenectomy, showed positive...
The World Health Organization (WHO) proposed an updated reporting system for pancreaticobiliary cytology, which moves low-grade malignancies to "positive malignancy" group and serous cystadenoma "negative group. WHO also created two new categories, namely, pancreatic neoplasia-low grade (PaN-Low) neoplasia-high (PaN-High), includes neoplastic mucinous cysts stratifies them according their cytologic atypia. risk of malignancy (ROM) the categories needs be defined.
This study was designed to identify the effect of pentoxifylline on trinitrobenzene sulfonic acid (TNBS)-induced colitis in rats.Forty-two female Wistar rats were randomly divided into 7 groups: group A, TNBS + intraperitoneal (IP) pentoxifylline; B, IP saline; C, intrarectal (IR) D, IR E, TNBS; F, saline G, saline. Pentoxifylline given daily for 3 days before or 6 after induction colitis. Rats killed days.IP and similarly significantly reduced damage histopathological scores. attenuated...