A5042962967- Epilepsy research and treatment
- Pharmacological Effects and Toxicity Studies
- EEG and Brain-Computer Interfaces
- Neonatal and fetal brain pathology
- Neuroscience and Neuropharmacology Research
- Diet and metabolism studies
- Metabolism and Genetic Disorders
- Genetics and Neurodevelopmental Disorders
- Sleep and Wakefulness Research
- Cerebral Venous Sinus Thrombosis
- Traumatic Brain Injury and Neurovascular Disturbances
- Psychosomatic Disorders and Their Treatments
- Infant Development and Preterm Care
- Pregnancy and Medication Impact
- Facial Nerve Paralysis Treatment and Research
- Infectious Encephalopathies and Encephalitis
- Neurological Complications and Syndromes
- Vagus Nerve Stimulation Research
- Virology and Viral Diseases
- Peripheral Neuropathies and Disorders
- Intracranial Aneurysms: Treatment and Complications
- Attention Deficit Hyperactivity Disorder
- Long-Term Effects of COVID-19
- Testicular diseases and treatments
- Folate and B Vitamins Research
Gazi University
2016-2025
Creative Commons
2021-2022
Gazi Hastanesi
2012-2019
Ministry of Health
2015
King's College London
2013
Karadeniz Technical University
2011
Turkish Society of Cardiology
2011
Hacettepe University
2009
Ankara University
2009
Akdeniz University
2009
Acute disseminated encephalomyelitis (ADEM) is the most common demyelinating disorder of childhood. Its clinical features, prognosis and treatment vary in different reports.
EXamining everolimus In a Study of Tuberous sclerosis 3 (EXIST-3) demonstrated significantly reduced seizure frequency (SF) with vs placebo. this study, we evaluate the long-term efficacy and safety for tuberous complex (TSC)-associated treatment-refractory seizures.After completion core phase, patients could enter an open-label extension phase receive (target exposure, 3-15 ng/mL) ≥48 weeks. Efficacy end points included change from baseline in average weekly SF expressed as response rate...
Methylphenidate is commonly believed to lower seizure threshold. The safe use of methylphenidate has not been clarified in patients with attention-deficit hyperactivity disorder (ADHD) and concomitant active or electroencephalographic (EEG) abnormalities. Patients ADHD seizures ( n = 57) EEG abnormalities 62), 6 16 years age, were included the study. safety efficacy treatment antiepilepsy drugs combined determined by assessing frequency, changes symptoms, Conners' Rating Scales, differences,...
The aim of this cross-sectional study was to determine the prevalence cerebral palsy (CP) among children in Turkey between ages 2 and 16 years. Samples were selected from cities, towns, districts, villages using cluster sampling method; 41861 selected. Data collected by parental interview physical examination. One hundred eighty-six identified with CP. CP determined as 4.4 per 1000 live births included postnatally acquired Origin classified prenatal 49 (26.6%), perinatal/neonatal 34 (18.5%),...
Dual energy X-ray absorptiometry (DXA) was used to assess lumbar spine (L2-4) and femoral neck bone mineral density (BMD) in 36 children taking either carbamazepine or valproic acid for longer than one year, generalized idiopathic epilepsy. Patients were matched with controls. Biochemical parameters of metabolism also measured. BMD values at both the femur groups not significantly different from that control group. Serum levels calcium subnormal alkaline phosphatase high Urinary lower group...
The aim of this cross-sectional study was to determine the prevalence epilepsy in Turkey among children between ages 0 and 16 years. population consisted 24,773,569 living Turkey. Because childhood is reported be 0.001 1% literature, sample size determined as 48,260, with 0.05 error type I 0.10 2 (power 0.90), effect 2. With cluster sampling method, samples were selected from cities, towns, districts, villages, 46,813 (97%) reached. questionnaire contained sections individual informational...
The aim of this study was to evaluate the effects short-term oxcarbazepine (OXC) and valproate (VPA) monotherapy on thyroid functions in children.Fifty-five newly diagnosed epileptic children with normal (confirmed thyrotropin releasing hormone stimulation test) participated study. VPA treatment started 30 patients OXC 25 patients. Serum thyroxine (T(4)), free (fT(4)), triiodothyronine (T(3)), (fT(3)), reverse T3 (rT(3)), peroxidase antibodies (TPO-ab), urine iodine levels were evaluated at...
Abstract Background Tuberous sclerosis complex (TSC) is a rare multisystem autosomal dominant disorder caused by pathogenic variants in either the TSC1 or TSC2 gene. Common manifestations of TSC have been grouped into major and minor clinical diagnostic criteria assessed routine workup. However, case studies point towards existence disease to potential association with malignant tumors. In this study we sought characterize malignancies using large cohort patients. Methods TuberOus SClerosis...
Weight gain is a common side effect of valproate treatment. The potential mechanisms valproate-associated weight are not yet clear. Decreased blood glucose level, impairment β-oxidation fatty acids, and increased insulin levels some the possible mechanisms. aim present study to evaluate role insulin, leptin, neuropeptide Y in valproate-related epileptic children. In 20 children treated with before treatment after follow-up period 3 6 months, body mass index fasting ratio were calculated...
The aim of the present study was to investigate effects carbamazepine (CBZ), oxcarbazepine (OXC), and valproic acid (VPA) on thyroid function volume in epileptic children.Fifty-three children (age, 3-17 years) treated with OXC (n = 10), CBZ 12), or VPA 31) at least for 1 year were evaluated terms hormones, thyroid-stimulating hormone (TSH) levels, response thyrotropin-releasing (TRH) stimulation test, volumes.The patients groups had similar total thyroxin (TT4) free T4 (fT4) median levels...