Ahmet Taner Sümbül

ORCID: 0000-0002-5573-906X
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About
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Research Areas
  • Lung Cancer Treatments and Mutations
  • Lung Cancer Research Studies
  • Cancer Treatment and Pharmacology
  • Cancer Immunotherapy and Biomarkers
  • Inflammatory Biomarkers in Disease Prognosis
  • Prostate Cancer Treatment and Research
  • Cancer-related molecular mechanisms research
  • Lung Cancer Diagnosis and Treatment
  • HER2/EGFR in Cancer Research
  • Bladder and Urothelial Cancer Treatments
  • Cholangiocarcinoma and Gallbladder Cancer Studies
  • Metastasis and carcinoma case studies
  • Gastric Cancer Management and Outcomes
  • Colorectal Cancer Treatments and Studies
  • Plant Physiology and Cultivation Studies
  • Horticultural and Viticultural Research
  • Cancer Diagnosis and Treatment
  • Neuroendocrine Tumor Research Advances
  • Urinary and Genital Oncology Studies
  • Phytochemicals and Antioxidant Activities
  • Lymphoma Diagnosis and Treatment
  • Multiple and Secondary Primary Cancers
  • Brain Metastases and Treatment
  • Chronic Lymphocytic Leukemia Research
  • Gastrointestinal Tumor Research and Treatment

Başkent University
2015-2025

Sivas Cumhuriyet Üniversitesi
2020-2025

Adana Hospital
2018-2023

Van Yüzüncü Yıl Üniversitesi
2022

Mustafa Kemal University
2012-2021

Istanbul Medipol University
2021

Bakırköy Psychiatric Hospital
2021

Sağlık Bilimleri Üniversitesi
2021

University of Health Science
2021

Acıbadem University
2021

Leukocytosis is thought to be directly associated with the pathogenesis of atherosclerosis and metabolic syndrome. Increased white blood cell (WBC) count related cardiovascular disease in patients type 2 diabetes mellitus; raised neutrophil lymphocyte ratio (NLR) There little information, however, concerning a correlation between glycosylated haemoglobin (HbA1c) NLR. The aim present study was investigate relationship NLR glucose regulation.This retrospective conducted mellitus, divided into...

10.1177/0300060513516944 article EN cc-by-nc Journal of International Medical Research 2014-02-24

Overexpression of Hox transcript antisense intergenic RNA (HOTAIR), a long non-coding (lncRNA), is associated with cancer cell proliferation, invasion, progression, and metastasis as well poor survival in variety human cancers including breast (BC). A common functional single nucleotide polymorphism (SNP) rs920778 (T → C) the intronic enhancer HOTAIR has been reported to influence expression predisposition, but association BC susceptibility clinicopathological features yet be investigated....

10.1007/s13277-014-3028-0 article EN Tumor Biology 2015-01-13

This study was conducted over two growing seasons (2010 and 2011) to evaluate effects on fruit quality phytochemical properties of new Turkish cultivars, hybrid between Irano-Caucasian- European eco-geographic groups, some important apricot cultivars in the eastern Mediterranean region Turkey. Fruit characteristics, sensory traits, parameters were investigated. The data showed that considerable variation existed Turkish, foreign based genotypes seasons. cultivar ‘Çağataybey’ contained...

10.15835/nbha4028044 article EN cc-by Notulae Botanicae Horti Agrobotanici Cluj-Napoca 2012-09-24

Hox transcript antisense intergenic RNA (HOTAIR), a long non-coding (lncRNA), is pervasively overexpressed and correlated with tumor invasion, progression, metastasis, poor prognosis in various human cancers including breast cancer (BC) that plays role as an oncogenic molecule. A common functional single-nucleotide polymorphism (SNP) (rs12826786 C>T) at the HOTAIR promoter has been reported to influence expression gastric adenocarcinoma susceptibility, but relation of rs12826786 C>T BC...

10.1007/s13277-015-4430-y article EN Tumor Biology 2015-11-14

Central nervous system (CNS) metastases can be seen at a rate of 30% in advanced stages for patients with non-small cell lung cancer (NSCLC). Growing evidence indicates the predictive roles driver gene mutations development brain (BM) recent years, meaning that oncogene-driven NSCLC have high incidence BM diagnosis. Today, 3rd generation targeted drugs intracranial efficacy, which cross blood-brain barrier, made positive contribution to survival these an increased propensity BM. It is...

10.1038/s41598-024-56046-w article EN cc-by Scientific Reports 2024-03-09

Türkiye has a unique position globally as it connects the Asian and European continents. In this study, genetic diversity of total 27 mulberry (Morus alba) genotypes collected from northeastern was evaluated in terms morphological, biochemical, molecular characteristics. fruits genotypes, fruit weight (FW) ranged 2.00 to 5.13 g, width (Fw) 12.64 16.93 mm, length (FL) 20.89 32.34 mm. Total soluble solids (TSS) 16.56% 26.00%, pH 3.87 5.10, phenolic content (TPC) 72.69 171.34 mg GAE/100...

10.3390/horticulturae11030298 article EN cc-by Horticulturae 2025-03-10

Background and Objectives: This study aimed to evaluate the effectiveness of immunotherapy compared chemotherapy across different treatment lines in patients with malignant pleural mesothelioma. It also sought identify factors influencing success immunotherapy, such as histological subtype, PD-L1 expression, type asbestos exposure, metastatic status. Materials Methods: A retrospective analysis was conducted 60 diagnosed Data on age, gender, exposure were collected for all expression assessed...

10.20944/preprints202503.0747.v1 preprint EN 2025-03-11

Background and Objectives: This study aimed to evaluate the effectiveness of immunotherapy compared chemotherapy across different treatment lines in patients with pleural mesothelioma. It also sought identify factors influencing success immunotherapy, such as histological subtype, PD-L1 expression, type asbestos exposure, metastatic status. Materials Methods: A retrospective analysis was conducted 60 diagnosed Data on age, gender, exposure were collected for all expression assessed a subset...

10.3390/medicina61040638 article EN cc-by Medicina 2025-03-31

MicroRNAs (miRNAs) are important factors during tumorigenesis by affecting posttranscriptional gene expression. miRNA 204 (miR-204) is a frequently investigated in different types of cancers. According to literature, autophagy has dual roles cancer, acting as both tumor suppressor and cell survival agent. Also, the current data suggests that activated human colorectal cancer cells enhances aggressiveness cells. So, our aim investigate potential effect miR-204-5p on associating its expression...

10.1007/s13277-014-2596-3 article EN Tumor Biology 2014-09-10
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