A5065094627- Bladder and Urothelial Cancer Treatments
- Urinary and Genital Oncology Studies
- Cancer Immunotherapy and Biomarkers
- Vasculitis and related conditions
- Systemic Sclerosis and Related Diseases
- Cardiovascular Health and Disease Prevention
- Cancer Genomics and Diagnostics
- Multiple and Secondary Primary Cancers
- Ocular Diseases and Behçet’s Syndrome
- Cardiovascular Function and Risk Factors
- Pancreatic and Hepatic Oncology Research
- Intraperitoneal and Appendiceal Malignancies
- Oral health in cancer treatment
- Inflammatory Biomarkers in Disease Prognosis
- RNA regulation and disease
- Cell death mechanisms and regulation
- Healthcare Education and Workforce Issues
- Management of metastatic bone disease
- Cardiac Imaging and Diagnostics
- Cancer Risks and Factors
- Retinal Imaging and Analysis
- Inflammasome and immune disorders
- Appendicitis Diagnosis and Management
- Family Support in Illness
- Colorectal Cancer Surgical Treatments
Kayseri Eğitim ve Araştırma Hastanesi
2021-2024
Pamukkale University
2013-2022
Advanced bladder cancer (BC) is associated with an inflammatory nature and poor prognosis Inflammatory biomarkers are potential predictors in BC. We conducted a study to assess the prognostic value of pretreatment neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte (PLR), lymphocyte-to-monocyte (LMR) advanced cancer.A total 226-patients muscle-invasive BC (MIBC) were included. Overall (OS) progression-free survival estimated using Kaplan-Meier method log-rank test was used for...
Background:: Diffusion Magnetic Resonance Imaging (MRI) is a useful method to evaluate tumor biology and microstructure. The apparent diffusion coefficient (ADC) value correlates negatively with the cellular density of tumor. Objective:: This study aimed investigate effectiveness ADC histogram analysis in showing relationship between breast cancer prognostic factors parameters. Methods:: retrospective observational descriptive study. parameters were evaluated all volumes 67 patients....
Nailfold videocapillaroscopy (NVC) is a diagnostic method for evaluating the microvasculature. Behçet's disease (BD) can affect vessels of all types and sizes. We performed NVC in 82 randomly selected patients with BD. was eight fingers (excluding thumbs) 200× magnification. Of BD, 75 had at least one capillaroscopic change, including tortuosity (91.5%), bizarre capillaries (9.8%), microhemorrhages four (4.9%) mega capillary two (2.4%). The mean number capillaries/mm length nailfold group BD...
<b><i>Objective:</i></b> This study aimed to evaluate the correlation between fragmented QRS complex (fQRS), aortic stiffness, and diastolic dysfunction in hemodialysis patients. <b><i>Subjects Methods:</i></b> A sample of 56 patients who received treatment was stratified into 2 groups according their electrocardiography (ECG) patterns with or without fQRS. Baseline characteristics laboratory parameters were documented. Conventional...
<h3>Background</h3> Fibromyalgia syndrome (FMS) is a common chronic musculoskeletal disorder characterized by the presence of widespread pain and multiple tender points on physical examination. Deficiency vitamin D can cause similar symptoms. Studies regarding FMS relationship have been done in recent years. Although some studies determined this relationship, other failed to do so. <h3>Objectives</h3> We aimed evaluate between serum parathyroid hormone (PTH) levels clinical findings...
Background: Triple-negative breast cancer (TNBC) is defined as tumors without estrogen receptor (ER), progesterone (PR), and human epidermal growth factor 2 (HER2) expression. This associated with higher rates of recurrence risk when compared to other subtypes cancers. In this study, we aimed explore the basic clinicopathological characteristics, prognosis, patterns TNBC patients. Methods: current forty-five female patients operated on for in General Surgery Clinic Kayseri City Training...
First-line treatments for metastatic pancreatic cancer are chemotherapy regimens consisting of 5-fluorouracil or gemcitabine; however, there no biomarkers to help determine which patients might benefit from treatment regimens. We aimed show that microRNAs let-7c and 7d can be used as independent predictive cancer.A total 55 who had first-line with FOLFIRINOX gemcitabine+capecitabine were included. Patients divided into groups based on let-7d levels let-7c-7d high FOLFIRINOX, let7c-7d...
451 Background: Anti-tumor activity and manageable safety profile of atezolizumab (ATZ) has been demonstrated in the previous clinical trials patients with locally advanced or metastatic platinum-resistant urothelial carcinoma. In this study, we reported results real-life data carcinoma Turkey who were treated ATZ. Methods: Data registered to ATZ Expanded-Access Program at least one course from 36 oncology centers collected. The primary endpoint was overall response rate (ORR); secondary...
409 Background: In the current study, we evaluated whether response first-line chemotherapy could impact atezolizumab benefit in terms of rate and overall survival patients with metastatic urothelial carcinoma. Methods: this present retrospective analysis 105 cancer treated ATZ after progression on chemotherapy. The association between to was assessed using Fisher’s exact test. Overall (OS) estimated by Kaplan-Meier method. Univariate used identify clinical laboratory factors that...
The aim of the study was level anxiety, depression and alexithymia in patients with rheumatoid arthritis (RA). Alexithymia is defined as difficulty verbal expression feelings. more common seen chronic temporary health problems. One hundred forty eight a healthy subject were included into study. assessed Toronto Scale- 20 (TAS-20). Depression anxiety disorders severity quality life (QoL) Beck Inventory (BDI), Anxiety (BAI), World Health Organization Quality Life Assessment- Brief...
<h3>Background</h3> Behçet's disease is a systemic vasculitis with the involvement of all kinds veins and arteries characterized by repeating mucocutaneus ocular involvement. <h3>Objectives</h3> We aimed to determine microvascular abnormalities in Behçet patients nailfoldvideocapillaroscopy. <h3>Methods</h3> included 82 who were diagnosed according international diagnosis criteria. Patients reviewed about smoking, Raynaud's phenomena ischemic ulcers. had comorbidities including hypertension,...
<h3>Background</h3> Familial Mediterranean Fever (FMF) is an inflammatory disease characterized by synovitis and pleurotic attacks. It autosomal recessive disorder, the exact etiology unknown. 7% of patients can have Henoch-Schönleinpurpura polyarthritis nodosa. <h3>Objectives</h3> We aimed to determine microvascular abnormalities in FMF with nailfoldvideocapillaroscopy. <h3>Methods</h3> included non-smoker 29 30 healthy individuals. Patients were reviewed about smoking, Raynaud's phenomena...
Lung cancer continues to be the leading cause of cancer-related deaths. 1 Only 15% all patients with lung have more than five years survival after diagnosis. 2Cytotoxic chemotherapy is standard first-line therapy for squamous cell cancer.More recent efforts been made identify novel biomarkers prediction prognosis and response chemotherapy.Intrinsic extrinsic apoptotic pathways use caspase steps.In intrinsic pathway, Bax Bak are activated by various stimuli through DNA damage or cellular...
Low-grade appendiceal mucinous neoplasms (LAMN) of the appendix have bland cytological features and well-differentiated morphology. Despite this, they may cause a pseudomyxoma peritonei (PMP) disease characterized by deposits in peritoneal cavity exhibit malignant behavior.In this study, we evaluated clinical course histopathological findings LAMN. The rate progression to PMP, factors affecting its development, cases with PMP were investigated.Twelve thousand forty-seven who underwent...
Aim. The current standard treatment of locally advanced rectal carcinoma is total mesorectal excision and postoperative adjuvant chemotherapy after neoadjuvant concurrent chemoradiotherapy (NCRT). Many studies have shown that pathological complete response (pCR) an important prognostic factor for patients receiving NCRT. therefore been conducted to increase pCR rates by changing the perioperative strategies. Prolonging time may be a reasonable way effectiveness NCRT, pCR, survival rates. We...