A5036416606- Inflammatory Biomarkers in Disease Prognosis
- Cancer, Lipids, and Metabolism
- HER2/EGFR in Cancer Research
- MicroRNA in disease regulation
- Cutaneous Melanoma Detection and Management
- Liver Disease Diagnosis and Treatment
- Cardiovascular Disease and Adiposity
- Education and Learning Interventions
- Cancer Treatment and Pharmacology
- Colorectal and Anal Carcinomas
- Biological Activity of Diterpenoids and Biflavonoids
- Peptidase Inhibition and Analysis
- Healthcare Education and Workforce Issues
- Health and Well-being Studies
- Neuroblastoma Research and Treatments
- Bladder and Urothelial Cancer Treatments
- Nonmelanoma Skin Cancer Studies
- Cancer Immunotherapy and Biomarkers
- Cancer-related molecular mechanisms research
- Ginseng Biological Effects and Applications
- Melanoma and MAPK Pathways
- Cancer Genomics and Diagnostics
- Retinal Imaging and Analysis
- Monoclonal and Polyclonal Antibodies Research
- Pancreatic and Hepatic Oncology Research
Pamukkale University
2021-2024
Our aim was to assess the efficacy of adjuvant programmed cell death protein-1 (PD-1) inhibitors and compare other treatments in patients with surgically resected stage III or IV acral melanoma. This study is a multicenter, retrospective analysis. We included 114 malignant melanoma who underwent surgery within past 10 years. analyzed effect on disease-free survival (DFS). The mean follow-up 40 months, during which 69 (59.5%) experienced recurrence. Among participants, 64 (56.1%) received...
Advanced bladder cancer (BC) is associated with an inflammatory nature and poor prognosis Inflammatory biomarkers are potential predictors in BC. We conducted a study to assess the prognostic value of pretreatment neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte (PLR), lymphocyte-to-monocyte (LMR) advanced cancer.A total 226-patients muscle-invasive BC (MIBC) were included. Overall (OS) progression-free survival estimated using Kaplan-Meier method log-rank test was used for...
Purpose:It is estimated that type 2 diabetes mellitus affects 530 million people worldwide and 10.5 per cent of these patients have diabetic retinopathy. This study aims to investigate the predictive value cardiometabolic control, GGT malnutrition-related inflammation markers for predicting Diabetic retinopathy prevalence prognosis.
 Materials Methods:Type Diabetes Mellitus who were consecutively admitted Internal Ophthalmology outpatient clinics included in this study. Clinical,...
We aimed to evaluate the efficacy and safety of trastuzumab emtansine in patients with metastatic breast cancer previously treated pertuzumab plus taxane. reviewed medical records who were diagnosed Human Epidermal Growth Factor Receptor 2 (HER-2) positive received then TDM-1 between January 2014 2021 from twenty- five centers. The Kaplan- Meier method estimated progression-free survival (PFS) overall (OS). Additionally, objective response rate (ORR), clinical benefit (CBR), evaluated. One...
Objective:We analysed the relationship between albumin and CRP related inflammation markers (Controlling nutritional status(Conut)score, lymphocyte factor(LA), albumin-bilirubin score (ALBI), highly sensitive modified Glasgow prognostic (Hs-mGPS), score(GPS)) locoregional treatment response in HCC. Materials methods:Among 180 HCC patients, 63 patients who underwent therapy were included this study. Albumin immuno-nutrition scores calculated by recording routine laboratory tests fourth eighth...
First-line treatments for metastatic pancreatic cancer are chemotherapy regimens consisting of 5-fluorouracil or gemcitabine; however, there no biomarkers to help determine which patients might benefit from treatment regimens. We aimed show that microRNAs let-7c and 7d can be used as independent predictive cancer.A total 55 who had first-line with FOLFIRINOX gemcitabine+capecitabine were included. Patients divided into groups based on let-7d levels let-7c-7d high FOLFIRINOX, let7c-7d...
Abstract
 Purpose:We evaluated the effect of pre-treatment inflammation response markers on overall survival (OS) and progression-free (PFS) in patients with locally advanced unresectable metastatic gastric cancer.
 Material Method:Patients cancer between January 2016 December 2021 were included. Among these patients, 114 ECOG (Eastern Cooperative Oncology Group) Performance status 0-2, who received at least one line chemotherapy, had no comorbidities brain metastases included...
Abstract
 Purpose: As systemic inflammatory indices and prognostic nutritional index are associated with poor prognosis in many tumor types, the goal of present study was to ascertain their effect along neutrophil/lymphocyte ratio, platelet/lymphocyte lymphocyte/monocyte C-reactive protein/albumin response on progression-free survival (PFS) overall (OS) hormone receptor-positive HER2-negative (HR+/HER2−) metastatic breast cancer patients before CDK4/6 inhibitor treatment. 
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Aim. The current standard treatment of locally advanced rectal carcinoma is total mesorectal excision and postoperative adjuvant chemotherapy after neoadjuvant concurrent chemoradiotherapy (NCRT). Many studies have shown that pathological complete response (pCR) an important prognostic factor for patients receiving NCRT. therefore been conducted to increase pCR rates by changing the perioperative strategies. Prolonging time may be a reasonable way effectiveness NCRT, pCR, survival rates. We...
Amaç: Over kanseri jinekolojik kanserler arasında en yüksek ölüm oranına sahip olan kanserdir.İnflamasyon temelli skorlar nötrofil lenfosit oranı (NLR), trombosit (PLR), CRP albümin (CRP/Alb) çoğu kanserde prognoz üzerine etkisi gösterilmiştir. Biz de bu çalışmada NLR, PLR, CRP/Albümin oranlarının over kanserinin prognozu etkisini değerlendirmeyi amaçladık. Gereç ve Yöntem: Çalışmamıza Eylül 2014 - Aralık 2020 tarihleri Pamukkale Üniversitesi Tıp Fakültesi Tıbbi Onkoloji Bilim Dalı...