A5007668098- Cancer Genomics and Diagnostics
- Inflammatory Biomarkers in Disease Prognosis
- Colorectal Cancer Treatments and Studies
- Genetic factors in colorectal cancer
- Gastric Cancer Management and Outcomes
- Cancer Immunotherapy and Biomarkers
- Lung Cancer Treatments and Mutations
- MicroRNA in disease regulation
- Colorectal and Anal Carcinomas
- Biomarkers in Disease Mechanisms
- Urinary and Genital Oncology Studies
- HER2/EGFR in Cancer Research
- Cancer survivorship and care
- Cardiac Health and Mental Health
- Colorectal Cancer Screening and Detection
- Caveolin-1 and cellular processes
- Dental Research and COVID-19
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Dental Education, Practice, Research
- Medical Education and Admissions
- Nutritional Studies and Diet
- Hippo pathway signaling and YAP/TAZ
- Cell death mechanisms and regulation
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pancreatic and Hepatic Oncology Research
Liv Hospital
2024
Bridge University
2024
Gaziantep Children's Hospital
2024
Moffitt Cancer Center
2022-2023
Education Training And Research
2023
Pamukkale University
2020-2022
Kayseri Eğitim ve Araştırma Hastanesi
2020
Advanced bladder cancer (BC) is associated with an inflammatory nature and poor prognosis Inflammatory biomarkers are potential predictors in BC. We conducted a study to assess the prognostic value of pretreatment neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte (PLR), lymphocyte-to-monocyte (LMR) advanced cancer.A total 226-patients muscle-invasive BC (MIBC) were included. Overall (OS) progression-free survival estimated using Kaplan-Meier method log-rank test was used for...
239 Background: The benefit of immunotherapy for patients with mCRC high tumor mutational burden (TMB-H) has been widely debated. In 2020, the FDA approved use pembrolizumab treatment TMB-H unresectable or metastatic solid tumors, defined as ≥10 mutations/Mb on a commercial tissue-based assay, based KEYNOTE 158 results. However, clinical value applying this universal cut off to needs further investigation. Methods: We queried Moffitt Cancer Center (MCC) databases MSS mCRC, harboring (tested...
<title>Abstract</title> Purpose The present study was conducted to investigate the cognitive functions, quality of life, and exercise compliance lung cancer patients given Callisthenic Exercises. Method A total 33 who were diagnosed with advanced included in after being randomly divided into two groups as Physical Activity Adherence (PAC) (Group 1) Home Exercise Training (HET) 2). participants Group performed prescribed Exercises under guidance a physiotherapist for 8 weeks. an booklet asked...
PURPOSE Syrian refugees (SRs) have had difficulties in the diagnosis, treatment, and follow-up of chronic diseases, such as cancer, because conflict region. The cancer diagnosis treatment process SR are also a matter curiosity. We aimed to compare demographic characteristics survival outcome data SRs Turkish citizens (TCs), colorectal (CRC) is one most common types seen with similar frequency globally. MATERIALS AND METHODS A total 421 patients CRC were included. Overall (OS) was estimated...
Aim: Fetuin-B, which is part of the fetuin family, has been demonstrated to be related with emergence insulin resistance. Here, we examined relationship between metabolic parameters in treatment-naive patients diabetes and B levels serum. Material Method: Individuals aged 30-65 years old who were diagnosed newly mellitus, had no chronic disease history, provided informed consent enrolled study. The clinical examined. Results: Forty recently type 2 diabetic individuals 43 controls analyzed...
First-line treatments for metastatic pancreatic cancer are chemotherapy regimens consisting of 5-fluorouracil or gemcitabine; however, there no biomarkers to help determine which patients might benefit from treatment regimens. We aimed show that microRNAs let-7c and 7d can be used as independent predictive cancer.A total 55 who had first-line with FOLFIRINOX gemcitabine+capecitabine were included. Patients divided into groups based on let-7d levels let-7c-7d high FOLFIRINOX, let7c-7d...
e15569 Background: Increased molecular profiling ability has resulted in the recognition of important actionable genes that can be used to direct targeted therapies colorectal cancers (CRC). Neurotrophin receptor tyrosine kinase (NTRK) gene fusions are one these alterations potentially with novel therapeutics. However, other biologically pathogenic NTRK alterations, including point mutations, not yet CRC. This study aimed characterize metastatic CRC patients. Methods: Molecular...
Abstract
 Purpose: As systemic inflammatory indices and prognostic nutritional index are associated with poor prognosis in many tumor types, the goal of present study was to ascertain their effect along neutrophil/lymphocyte ratio, platelet/lymphocyte lymphocyte/monocyte C-reactive protein/albumin response on progression-free survival (PFS) overall (OS) hormone receptor-positive HER2-negative (HR+/HER2−) metastatic breast cancer patients before CDK4/6 inhibitor treatment. 
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Lung cancer continues to be the leading cause of cancer-related deaths. 1 Only 15% all patients with lung have more than five years survival after diagnosis. 2Cytotoxic chemotherapy is standard first-line therapy for squamous cell cancer.More recent efforts been made identify novel biomarkers prediction prognosis and response chemotherapy.Intrinsic extrinsic apoptotic pathways use caspase steps.In intrinsic pathway, Bax Bak are activated by various stimuli through DNA damage or cellular...
e15568 Background: Next-generation sequencing (NGS) based molecular profiling technologies have revealed several oncogenic fusion genes that are actionable with small molecule inhibitors leading to practice change, particularly in lung cancer. The and clinical characteristics of these gene fusions not well defined colorectal cancer patients (CRC). In this study, we aimed define CRC who underwent profiling. Methods: Molecular tissue confirmed 917 were retrieved from the Moffit Cancer Center...
Aim. The current standard treatment of locally advanced rectal carcinoma is total mesorectal excision and postoperative adjuvant chemotherapy after neoadjuvant concurrent chemoradiotherapy (NCRT). Many studies have shown that pathological complete response (pCR) an important prognostic factor for patients receiving NCRT. therefore been conducted to increase pCR rates by changing the perioperative strategies. Prolonging time may be a reasonable way effectiveness NCRT, pCR, survival rates. We...
Amaç: Over kanseri jinekolojik kanserler arasında en yüksek ölüm oranına sahip olan kanserdir.İnflamasyon temelli skorlar nötrofil lenfosit oranı (NLR), trombosit (PLR), CRP albümin (CRP/Alb) çoğu kanserde prognoz üzerine etkisi gösterilmiştir. Biz de bu çalışmada NLR, PLR, CRP/Albümin oranlarının over kanserinin prognozu etkisini değerlendirmeyi amaçladık. Gereç ve Yöntem: Çalışmamıza Eylül 2014 - Aralık 2020 tarihleri Pamukkale Üniversitesi Tıp Fakültesi Tıbbi Onkoloji Bilim Dalı...