- Renal cell carcinoma treatment
- Cancer Immunotherapy and Biomarkers
- Bladder and Urothelial Cancer Treatments
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Treatments and Studies
- Cancer Treatment and Pharmacology
- Hepatocellular Carcinoma Treatment and Prognosis
- Metastasis and carcinoma case studies
- Breast Cancer Treatment Studies
- Lung Cancer Treatments and Mutations
- Prostate Cancer Treatment and Research
- Multiple and Secondary Primary Cancers
- Viral-associated cancers and disorders
- Ovarian cancer diagnosis and treatment
- Advanced Breast Cancer Therapies
- Cancer Genomics and Diagnostics
- Cancer, Lipids, and Metabolism
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Urinary and Genital Oncology Studies
- Cancer, Hypoxia, and Metabolism
- Cancer Diagnosis and Treatment
- Chronic Myeloid Leukemia Treatments
- Inflammatory Biomarkers in Disease Prognosis
- HER2/EGFR in Cancer Research
- Esophageal Cancer Research and Treatment
Ankara Onkoloji Eğitim ve Araştırma Hastanesi
2018-2025
Sağlık Bilimleri Üniversitesi
2019-2025
Memorial Ankara Hospital
2018-2024
Gazi University
2015-2024
Ministry of Health
2018-2020
Ankara Spine Center
2020
Güven Hospital
2020
Kutahya Saglik Bilimleri Universitesi
2019
Ali Osman Sonmez Oncology Hospital
2019
Erciyes University
2019
Aim: To investigate how COVID-19 fear and anxiety (COV-FA) affects chemotherapy adherence in patients with cancer. Materials & methods: The records of 3661 (CT) appointments were retrospectively reviewed. Results: CT postponement rates before after 11.6% 14.2%, respectively (p = 0.017). rate COV-FA-related telemedicine was lower than that (4.6% vs 17.4%; p 0.012). median time to come back treatment the COV-FA group 47 days (range 19–72 days). Advanced age (≥60 years) found be independent...
To evaluate the immunogenicity and safety of CoronaVac vaccine in patients with cancer receiving active systemic therapy.
708 Background: This study evaluates the real-world efficacy and safety of avelumab maintenance therapy in metastatic urothelial carcinoma (mUC) patients who have not progressed following first-line platinum chemotherapy, using data from EAP. Methods: The primary endpoint was overall survival (OS), progression-free (PFS) secondary endpoints included safety. PFS OS were estimated by Kaplan-Meier method. Results: One hundred seventeen received at least one cycle Avelumab. median number...
The identification of prognostic factors in patients with glioblastoma multiforme (GBM) represents an area increasing interest. Carbonic anhydrase IX (CA‐IX), a hypoxia marker, correlates tumor progression variety human cancers. However, the role CA‐IX GBM remains largely unknown. In present study, we evaluated patients. total, 66 consecutive who received concomitant chemoradiotherapy and adjuvant chemotherapy temozolomide were retrospectively reviewed, all for at least 3 months....
<b><i>Introduction:</i></b> The aim of the study was to evaluate impact systemic immune-inflammation index (SII) on prognosis and survival within International Metastatic Renal Cell Carcinoma Database Consortium (IMDC) score groups. <b><i>Methods:</i></b> records 187 patients with metastatic renal cell carcinoma (RCC) were reviewed retrospectively. SII calculated as follows: = Neutrophil × Platelet/Lymphocyte. categorized into 2 groups based a...
The prognosis of patients with advanced HCC can vary widely depending on factors such as the stage cancer, patient's overall health, and treatment regimens. This study aimed to investigate survival outcomes associated in hepatocellular carcinoma (HCC). In this retrospective study, data from 23 medical oncology clinics were analyzed. Progression-free (PFS) (OS) values estimated using Kaplan–Meier method. Prognostic which identified univariate analysis subsequently evaluated a multivariate...
Membraneous nephropathy (MN) is the most commonly occurring nephrotic syndrome in adults as well common paraneoplastic associated with solid tumors, and it mostly gastrointestinal system lung carcinomas. Accurate diagnosis important treatment of glomerulonephritis very varied from that idiopathic ones. In current report, a case patient was referred proteinuria edema diagnosed cancer, responded markedly to malignancy, improvement MN, presented. Active cancer present all patients MN. numerous...
Abstract To compare enzalutamide (E) and abiraterone acetate (AA) in terms of efficacy, survival to characterize prognostic factors affecting metastatic castration-resistant prostate cancer (mCRPC) patients. A total 250 patients treated with E or AA 5 centers were included. The number no specific antigen (PSA) decline was higher the group than that group, proportion a PSA ≥ 50% (p = 0.020). Radiological progression free (rPFS) overall (OS) significantly longer when compared < 0.001 p...
To investigate the role of surgical resection primary tumor on overall survival (OS) in advanced gastric cancer patients at time diagnosis.The rates metastatic whose was resected diagnosis were compared with nonresected.The median progression-free and OS operated nonoperated group 10 versus 6, 14 9 months, respectively (p < 0.001). In multivariate analysis, tumor, Eastern Cooperative Oncology Group performance status, second-line chemotherapy had a significant effect (hazard ratio [HR]: 0.52...
The addition of aflibercept to the fluorouracil and irinotecan (FOLFIRI) regimen significantly improved clinical outcomes in patients with metastatic colorectal cancer (CRC) previously treated oxaliplatin. We aimed investigate efficacy safety second-line FOLFIRI combination CRC real-life experience.
Introduction To investigate the level of psychological resilience and impact attachment styles on degree to distress in patients with cancer receiving chemotherapy. Methods Patients chemotherapy were included study. Participants requested complete Relationship Scales Questionnaire (RSQ), Resilience Scale for Adults (RSA), a personal information form during data collection phase. One-way analysis variance (ANOVA) was used compare that parameter among styles. Logistic regression carried out...
Adjuvant chemotherapy for gastric cancer in elderly patients has same benefits as younger
Amaç: Biz bu çalışmamızda tip 2 diabetes mellitus (DM) gelişiminde rol aldığı öne sürülen nflamasyon, oksidatif stres ve insülin direncini gösteren parametrelerin prediyabetik dönemdeki düzeylerinin, serum rezistin düzeyi ile olan ilişkisini araştırmayı amaçladık.Yöntemler: Rezistin; son yıllarda keşfedilmiş, yağ dokusundan salgılanan adipokindir.Son dönemde yapılan çalışmalar obeziteyle ilişkili insulin direncinde önemli rolünün olduğunu göstermiştir.Çalışmamıza
Objective: To evaluate the prognostic role of systemic immune-inflammation index (SII), neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte (PLR) in patients who received platin-pemetrexed combination therapy and/or maintenance pemetrexed therapy.
Pazopanib is an effective treatment for advanced renal cell carcinoma and soft tissue sarcoma. Besides classical adverse events of this drug class, hepatotoxicity has been described as a frequent side effect. The aim the present study was to evaluate effect pazopanib on liver in experimental rat model. Sixteen Wistar albino rats were divided into 3 groups: toxicity induced with (10 mg/kg) administered 28 days (group 2) or 56 3) orally by gavage. Group 1 (control group) received only...
Aims: In this multicenter study, the authors aimed to determine real-life efficacy and safety of first-line alectinib. Materials & methods: This retrospective trial included advanced-stage, ALK-positive non-small-cell lung cancer patients who were treated with alectinib in terms ALK-tyrosine kinase inhibitors, regardless previous chemotherapy. The co-primary end points progression-free survival both for all treatment-naive population. secondary overall response rate, survival, rate CNS...