A5013941417- Testicular diseases and treatments
- Renal cell carcinoma treatment
- Cancer Immunotherapy and Biomarkers
- Inflammatory Biomarkers in Disease Prognosis
- Lung Cancer Treatments and Mutations
- Multiple Myeloma Research and Treatments
- Multiple and Secondary Primary Cancers
- Colorectal Cancer Treatments and Studies
- Angiogenesis and VEGF in Cancer
- Sarcoma Diagnosis and Treatment
- Apelin-related biomedical research
- Lung Cancer Diagnosis and Treatment
- Cancer Genomics and Diagnostics
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cancer Treatment and Pharmacology
- Lymphoma Diagnosis and Treatment
- Antiplatelet Therapy and Cardiovascular Diseases
- Glioma Diagnosis and Treatment
- Renal and Vascular Pathologies
- Hepatocellular Carcinoma Treatment and Prognosis
- HER2/EGFR in Cancer Research
- Cancer, Lipids, and Metabolism
- Renal and related cancers
- Urologic and reproductive health conditions
- Ovarian cancer diagnosis and treatment
Bolu Abant İzzet Baysal University
2025
Gülhane Askerî Tıp Akademisi
2017-2024
Sağlık Bilimleri Üniversitesi
2017-2024
Military Medical Academy
2024
University of Health Sciences Antigua
2021-2022
Antalya Eğitim ve Araştırma Hastanesi
2022
University of Health Sciences
2021
Istanbul Medeniyet University
2018
Ministry of Health
2018
Turkish Armed Forces
2011
To evaluate the immunogenicity and safety of CoronaVac vaccine in patients with cancer receiving active systemic therapy.
ABSTRACT This study tested the impact of troughing on detection rates MB2 canals with and without calcifications. Traditional access cavities were prepared was recorded in 200 maxillary molars selected based micro‐CT scans. In specimens, orifice not detected; performed. The number negotiated compared using McNemar's test. After traditional cavity preparation troughing, operator detected 142 specimens (82%). Troughing remaining led to further identification 16 canals, increasing rate 91%....
Introduction and aim To investigate the effect of prognostic nutritional index on treatment response survival in patients with metastatic renal cell cancer. Methods We retrospectively analyzed modalities; demographic, clinical pathological features 396 RCC index. Based median value, were grouped as having low high values. Kaplan-Meier method was used for analysis, Cox-regression analysis multivariate analysis. Results The overall 39 months (95% CI 26.1–51.8), 28 17.9–38) 7 4.7–9.2)...
The aim of the study was to evaluate real-world clinical outcomes atezolizumab and bevacizumab (Atez/Bev) as initial therapy for advanced hepatocellular carcinoma (HCC). We retrospectively analyzed 65 patients treated with Atez/Bev HCC from 22 institutions in Turkey between September 2020 March 2023. Responses were evaluated by RECIST v1.1 criteria. median progression-free survival (PFS) overall (OS) calculated using Kaplan–Meier method. Cox regression model employed conduct multivariate...
This study aims to investigate the prognostic value of systemic immune-inflammation index (SII)and its impact on survival in patients with metastatic renal cell carcinoma (mRCC). A total 706patients mRCC treated tyrosine kinase inhibitors (TKIs)between January 2007 and June 2020 (i.e., sunitinib, pazopanib) were included this study. SII was calculated 621 following formula:[neutrophil (cellsx109/L) x platelet (cellsx109/L)] / lymphocyte (cellsx109/L).All classified into SII-high SII-low...
Aim: To investigate the efficacy and safety of bevacizumab in patients with recurrent low-grade serous ovarian carcinoma. Materials & methods: The data who received at least two cycles combination chemotherapy were retrospectively recorded. Results: median age 51 was 56 (range: 33-75) years. complete response rate 10.4% partial 43.7%. objective 54.1%. Median progression-free survival 15.9 months (95% CI: 9.1-22.6) overall 42.5 37.2-47.8). Conclusion: Bevacizumab is an effective option for treating
Background To describe the prognostic value of neutrophil–lymphocyte ratio and its effect on survival in patients with advanced renal cell carcinoma. Methods We retrospectively analyzed 331 patients. The cut-off was specified as “3” which is mostly close—and also clinically easily applicable—to median level our study group. High group identified >3 (n = 160) low ≤3 163). Results A total (with 211 male 120 female) were enrolled to study. age 58. International Metastatic RCC Database...
The clinical effect of angiostatin in diabetes mellitus (DM) patients receiving insulin is a meaningful gap the literature. In this study, we aimed to show levels and significance DM insulin.This case-control study. Serum were determined by ELISA. A total 83 people consisting healthy subjects (n = 36) with diagnosis therapy 47) included study.The mean group significantly higher than those control (86.0 ± 68.1 ng/mL 58.0 22.4 ng/mL, respectively; P 0.011). Significantly lower metformin...
To show the levels of vascular endothelial growth factor (VEGF), soluble receptor-1 (sVEGFR-1) in patients with end-stage renal disease (ESRD) and to associations clinical findings such as demographic features, laboratory findings, comorbidities, medications.A total 73 people, consisting ESRD (n=38) healthy subjects (n=35) Gulhane Education Research Hospital, Ankara, Turkey, were included this cross-sectional study between years 2011 2013. Blood samples obtained plasma VEGF, sVEGFR-1...
To investigate the clinical significance of VEGF, sVEGFR-1 in heart failure reduced ejection fraction (HFrEF) and mid-range (HFmrEF) patients. Methods: A total 104 people consisting HFrEF HFmrEF patients (n=54) healthy (n=50) subjects were included this comparative cross-sectional study. The study took place Gulhane Training Research Hospital, Ankara, Turkey, between 2011 2013. Serum sVEGFR-1, plasma pro-BNP analysis transthoracic echocardiography performed. Results: average level was...
Aims: In this multicenter study, the authors aimed to determine real-life efficacy and safety of first-line alectinib. Materials & methods: This retrospective trial included advanced-stage, ALK-positive non-small-cell lung cancer patients who were treated with alectinib in terms ALK-tyrosine kinase inhibitors, regardless previous chemotherapy. The co-primary end points progression-free survival both for all treatment-naive population. secondary overall response rate, survival, rate CNS...
Aim: The authors present real-world data on the efficacy and safety of nivolumab in patients with metastatic renal cell carcinoma (mRCC). Methods: Turkish Oncology Group Kidney Cancer Consortium (TKCC) database includes mRCC from 13 cancer centers Turkey. Patients treated second line beyond were extracted TKCC database. Results: A total 173 included. rates second, third, fourth fifth lines 47.4%, 32.4%, 14.5% 5.7%, respectively. median overall survival progression-free 24.2 months 9.6...
<title>Abstract</title> Background We aimed to evaluate the survival analysis, response rates and factors affecting high-dose chemotherapy (HDCT) autologous stem cell transplantation (OSCT) in patients with relapsed/refractory extragonadal germ tumours. Methods The study included diagnosed tumors who underwent HDCT + ASCT between November 2016 January 2023 at Gülhane Training Research Hospital. Clinical characteristics follow-up data were retrospectively analyzed from patient records...
Extragonadal germ cell tumours have a more unfavourable prognosis than gonadal tumours. We aimed to evaluate the survival analysis, response rates, and factors affecting responses high-dose chemotherapy (HDCT) autologous stem transplantation (ASCT) in patients with relapsed/refractory extragonadal
Background: Salvage treatment options have not been validated in relapsed or refractory germ cell tumors. Moreover, the study populations including these patients different heterogeneities. This aimed to evaluate efficacy and safety of three cycles TIP sequential high-dose chemotherapy with testicular non-seminomatous tumors who had a course after first-line platinum-based chemotherapy. Methods: Data 141 underwent followed by HDCT due relapsed/refractory gonadal NSGCTs cisplatin-based...
Abstract Objectives The literature about atypical cells in automated urine analyzers begins with the introduction of Sysmex UN. While modern urinalysis instruments report various kinds epithelial cells, presence has not been considered. This study aims to observe efficiency parameter on UN Automated Urine Analyzer respect customary manual cytology. Methods patients any indication for a cystoscopy examination were enrolled between March 2022 and October 2022. Voided samples gathered before...
Lung involvement, an uncommon initial presentation of Hodgkin Lymphoma (HL), may appear as primary or secondary pulmonary HL. Although the combination Brentuximab vedotin (BV) with AVD is suggested alternative treatment to combinations including bleomycin for patients involvement. The efficacy and adverse effects BV have not been specialized on There insufficient data about neutrophil lymphocyte ratio (NLR) cases treated BV. We performed this retrospective study evaluate toxicity in HL...