A5002448212- Colorectal Cancer Treatments and Studies
- Lung Cancer Treatments and Mutations
- Lung Cancer Research Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Surgical Treatments
- Lung Cancer Diagnosis and Treatment
- Metastasis and carcinoma case studies
- Pancreatic and Hepatic Oncology Research
- Gastrointestinal Tumor Research and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Neuroendocrine Tumor Research Advances
- Cancer Immunotherapy and Biomarkers
- Inflammatory Biomarkers in Disease Prognosis
- Cancer Treatment and Pharmacology
- Cancer Diagnosis and Treatment
- Cancer survivorship and care
- Colorectal and Anal Carcinomas
- Sarcoma Diagnosis and Treatment
- Multiple and Secondary Primary Cancers
- Cancer-related Molecular Pathways
- Neutropenia and Cancer Infections
- Cutaneous Melanoma Detection and Management
- Cancer, Lipids, and Metabolism
- Neuroblastoma Research and Treatments
Dokuz Eylül University
2015-2024
Dokuz Eylül Üniversitesi Hastanesi
2024
Izmir University
2021
Memorial Sisli Hospital
2021
Adnan Menderes University
2018
Van Yüzüncü Yıl Üniversitesi
2015
Atatürk University
2013
Pamukkale University
2007-2008
Abstract Purpose : Burnout is associated with decreased job performance and commitment, predicts stress‐related health problems, low career satisfaction. The specific objectives in our study were to assess the levels of burnout investigate interrelationships between demographic characteristics health‐care professionals working cancer patients Turkey. Methods A questionnaire‐based was conducted 77 physicians 56 nurses an oncology clinic at university hospital. We used quantitative survey...
<b><i>Background:</i></b> Several studies evaluating the prognostic factors of gastrointestinal and pancreatic neuroendocrine tumors (GEP-NETs) have been published. The neutrophil-lymphocyte ratio (NLR) platelet-lymphocyte (PLR) accepted as for cancer patients. <b><i>Materials Methods:</i></b> This study included 132 patients diagnosed with GEP-NETs. Peripheral blood samples were collected before pretreatment period....
Breast and cervical cancer are the most common causes of mortality among women worldwide, but actually they largely preventable diseases. There is limited data on breast knowledge, screening practices attitudes nurses in Turkey. A self-administered questionnaire was used to investigate knowledge attitude risk factors as well programmes such self-examination (BSE), clinical examination, mammography (MMG) papanicolaou (pap) smear test. In total, 125 out 160 participated study (overall response...
Abstract Aim The aim was to compare the pathological complete response (pCR) rate at 8 compared 12 weeks’ interval between completion of neoadjuvant chemoradiotherapy (CRT) and surgery in patients with locally advanced rectal cancer. Method This a randomized trial which included total 330 from two institutions. Patients (T3‐4N0M0, TxN+M0) cancer were into 8‐ 12‐week groups. All received long‐course CRT (45 Gy 1.8 fractions concomitant oral capecitabine or 5‐fluorouracil infusion). Surgery...
Prognostic nutritional index (PNI), which is calculated using the albumin level reflecting status and lymphocyte count immune status, useful in showing immunological related to survival prognosis many cancers. In this study, we aimed evaluate biomarker potential effect of PNI determining metastatic castration-sensitive prostate cancer (mCSPC). This retrospective observational study included complete data 108 patients with mCPSC who were treated for at least three months between 1 January...
We aimed to identify the incidence of cardiac events with capecitabine treatment.The study included 52 patients (median age 59 years) cancer treated at our Medical Oncology Clinic between 2009 and 2010. Cardiac from treatment were classified into 4 groups: symptoms, physical signs, electrocardiography (ECG) findings, severe adverse effects.The received either single-agent or a combination chemotherapy including capecitabine. After initiation capecitabine, 18 (34.6%) had new onset...
To evaluate the cardiotoxicity of LV5FU2 regimen (bolus plus infusional 5-fluorouracil/folinic acid) treatment by non-invasive methods such as echocardiography, plasma troponin I (TnI) level, QT interval and dispersion on ECG.Twenty-two patients with gastrointestinal cancer who received chemotherapy were evaluated prospectively during 12 cycles chemotherapy. Plasma TnI assay ECG recording analyses performed before first cycle, at 24 h, each cycle until 6 every three thereafter. The longest...
The cardiac toxicity of LV5FU2 (de Gramont) regimen which is a widely used chemotherapy in gastrointestinal system cancers not well defined. We aimed to evaluate the impact this on rhythm. Two Holter ECG recordings were obtained all patients with treated as first-line (one before and second during first 24 h chemotherapy). Records reviewed for heart rate, rhythm, atrial premature complexes (APC), ventricular (VPC), grades according Lown-Wolf grading ST segment changes. evaluated 27 patients....
Background: To investigate epidermal growth factor receptor (EGFR) gene mutations in patients with non-small cell lung cancer (NSCLC) and to analyze any relationship clinicopathological features prognosis. Materials Methods: EGFR exons 18-21 48 specimens of paraffin-embedded tumor tissue from NSCLC were amplified by PCR, followed direct sequencing analysis links Results: detected 18 (42.6%) NSCLC. There 9 cases exon 20, 7 19 2 21. Mutations more frequently observed women (5/7 pts, 71.4%)...
Fluoropyrimidine-based chemotherapy is extensively used for the treatment of solid cancers, including colorectal cancer. However, fluoropyrimidine-driven toxicities are a major problem in management disease. The grade and type depend on demographic factors, but substantial inter-individual variation fluoropyrimidine-related toxicity partly explained by genetic factors. aim this study was to investigate effect dihydropyrimidine dehydrogenase (DPYD), thymidylate synthase (TYMS),...
Purpose. To determine the values of prognostic nutritional and inflammatory markers in chemotherapy outcomes survival patients with advanced nonsmall cell lung cancer (NSCLC) also secondary malnutrition cachexia. Methods. Twenty-five diagnosis aNSCLC were registered for prospective study. Malnutrition was determined by Subjective Global Assessment (SGA) performance status criteria Eastern Cooperative Oncology Group (ECOG). Before treatment, serum levels albumin, prealbumin, vitamin D, zinc...
The angiotensin-converting enzyme (ACE) plays an important role not only in the regulation of vascular homeostasis but also stimulation hematopoiesis. We aimed to evaluate association between insertion/deletion (I/D) polymorphism ACE gene and anemia at time diagnosis. enrolled 75 patients with non–small-cell lung cancer (NSCLC) 85 age- sex-matched healthy control participants. I/D was identified by using polymerase chain reaction from peripheral blood samples. Statistical analyses were...
The purpose of our study was to investigate the immunohistochemical expression TGF-beta1 and p27 in pancreatic adenocarcinomas compare findings with clinicopathological features survival. We also aimed evaluate context other cell cycle proliferation markers such as cyclin D1 Ki-67.We examined immunohistochemically 63 cases invasive ductal adenocarcinoma pancreas. Standard streptavidin-biotin immunperoxidase method used for immunostaining stained slides were microscopically using...
In non-small-cell lung cancer (NSCLC), stage of the disease is still most important prognostic factor. Other than stage, many biological markers and other factors are studied to define their effects on prognosis cancer. this study, we aimed evaluate expressions Bax bcl-2 genes which in apoptosis c-kit, a tyrosine kinase transmembrane receptor, as well searched response treatment modalities survival. Sixty-nine NSCLC cases' pathological samples were stained with specific Bax, c-kit dyes by...
The aims of the present study were to investigate distribution insertion/deletion (I/D) polymorphism angiotensin-converting enzyme (ACE) gene in breast cancer patients and association between ACE genotypes clinicopathologic features, as well their effects on prognosis. We assessed I/D polymophism by using polymerase chain reaction from peripheral blood healthy age-matched women. parameters obtained medical records. Of 57 patients, 31 (54.4%) had DD, 24 (42.1%) ID, 2 (3.5%) II genotypes. In...