- Prostate Cancer Treatment and Research
- Cancer, Lipids, and Metabolism
- Inflammatory Biomarkers in Disease Prognosis
- Cancer Immunotherapy and Biomarkers
- Lung Cancer Treatments and Mutations
- Lung Cancer Diagnosis and Treatment
- Liver Disease Diagnosis and Treatment
- Immune cells in cancer
- Liver Diseases and Immunity
- Cutaneous Melanoma Detection and Management
- Colorectal Cancer Treatments and Studies
- Mast cells and histamine
- Vascular Tumors and Angiosarcomas
- Melanoma and MAPK Pathways
- Pediatric Hepatobiliary Diseases and Treatments
- Cancer Genomics and Diagnostics
- Bone and Joint Diseases
- Cancer Diagnosis and Treatment
- Prostate Cancer Diagnosis and Treatment
- Eosinophilic Disorders and Syndromes
- CAR-T cell therapy research
- Bone health and treatments
Şanlıurfa Mehmet Akif İnan Eğitim ve Araştırma Hastanesi
2025
Dokuz Eylül University
2021-2024
Management of melanoma has changed significantly with the discovery targeted therapies and immune checkpoint inhibitors (ICI). Our aim in study is to determine which treatment alternatives, specifically dabrafenib plus trametinib ICIs, are effective adjuvant therapy as first-line metastatic therapy. This retrospective, multicenter included 120 patients diagnosed stage IIIB-IIID receiving both between 2007 2023. Data on clinicopathologic characteristics, regimens outcomes were collected....
Prognostic nutritional index (PNI), which is calculated using the albumin level reflecting status and lymphocyte count immune status, useful in showing immunological related to survival prognosis many cancers. In this study, we aimed evaluate biomarker potential effect of PNI determining metastatic castration-sensitive prostate cancer (mCSPC). This retrospective observational study included complete data 108 patients with mCPSC who were treated for at least three months between 1 January...
Background: In this paper, it was aimed to evaluate the biomarker potential as well effect of prognostic nutritional index (PNI), which is calculated using albumin level reflecting status and lymphocyte count immune status, in determining prognosis metastatic castration-sensitive prostate cancer (mCSPC).
 
 Methods: This retrospective observational study included complete data 108 patients with mCPSC who were treated for at least three months between January 1, 2010, June 2021. The...
Objective: Prostate cancer is the second common in men Turkey. We aimed to share our single center experience on characteristics of patients with metastatic castration sensitive prostate (mCSPC) and factors affecting survival.
 Materials Methods: Between January 2007 December 2020, 280 (aged 18 years older men) who applied diagnosis carcinoma were screened this retrospective cross-sectional study. Sociodemographic clinicopathological obtained retrospectively from hospital database. The...
Primary Biliary Cholangitis (PBC) is a chronic cholestatic liver disease typically diagnosed by elevated enzymes and positive anti-mitochondrial antibody (AMA) test. The clinical importance of AMA positivity in patients with normal unclear. aim this study was to determine the relationship between PBC detected individuals enzyme levels. files and/or AMA-M2 2009 2018 whose alkaline phosphatase (ALP) levels were below upper limit (ULN) at initial admission retrospectively analyzed. ALP all...
<title>Abstract</title> Background Denosumab, a RANK-ligand inhibitor, is an effectivetreatmentforfor bone metastasesfromsolidtumors.Unlikethebisphosphonates, it not excretedbythekidney. Little known, however, aboutitsefficacyandsafety in patientswith severe chronickidneydisease (CKD). Methods This study retrospective observational and was conducted as multicenter within the scope of Turkish Oncology Group (TOG) project. Patients with breast, prostate lung cancer who received denosumab...
<title>Abstract</title> Background To determine the relationship between SIRI, PIV and prognosis in metastatic Non-Small Cell Lung Cancer (NSCLC) to create a formula based on parameters that can be easily accessed daily practice. Methods A total of 126 patients diagnosed with NSCLC receiving systemic chemotherapy were evaluated. Laboratory values measured within 24 hours before initiation recorded. The immune-inflammation index (SIRI) was calculated using (neutrophil count × monocyte count)...
Renal cell carcinoma (RCC) can cause various paraneoplastic syndromes, including metabolic and hematologic disturbances. Paraneoplastic hypereosinophilia has been reported in a variety of solid tumors. Hypereosinophilia due to RCC is very rare only available as case reports the literature. A 66-year-old male patient's thoracoabdominal computed tomography (CT) performed showed an increase size right kidney heterogeneous contrasting mass approximately 12 cm × 9 cm, which formed lobulations its...
P rostate carcinoma is the most common cancer in men and second causing death world. [1]Metastatic prostate accounts for approximately 18% of all carcinomas.As a result new treatments developed recent years, survival times have exceeded 5 years.In metastatic castration-sensitive (mCSPC), androgen deprivation therapy (ADT) has been mainstay treatment since 1940s. [2]However, with ADT alone, patient varied.Some patients survived less than two Objectives: Prostate world.In this study, we will...
Abstract Objectives To compare the survival of first- and second-generation tyrosine kinase inhibitors (TKIs) in patients with rare EGFR exon 18 20 mutation-positive non-small cell lung cancer (NSCLC). Materials Methods We retrospectively evaluated characteristics 125 mutated NSCLC who received erlotinib or afatinib as first line treatment between 2012 2021 from 34 oncology centres. Since insertion is associated TKI resistance, these were excluded study. Results mutations seen 60%, 16%,...