A5057455821- Cancer survivorship and care
- Renal cell carcinoma treatment
- Lung Cancer Treatments and Mutations
- Metastasis and carcinoma case studies
- Inflammatory Biomarkers in Disease Prognosis
- Palliative Care and End-of-Life Issues
- Lymphoma Diagnosis and Treatment
- Lung Cancer Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Cancer Immunotherapy and Biomarkers
- Central Venous Catheters and Hemodialysis
- Immunotherapy and Immune Responses
- Pharmaceutical Practices and Patient Outcomes
- Chronic Lymphocytic Leukemia Research
- Gastric Cancer Management and Outcomes
- Cancer-related cognitive impairment studies
- Management of metastatic bone disease
- Patient-Provider Communication in Healthcare
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Childhood Cancer Survivors' Quality of Life
- CNS Lymphoma Diagnosis and Treatment
- Vaccine Coverage and Hesitancy
- Adrenal and Paraganglionic Tumors
- Blood groups and transfusion
- Hormonal Regulation and Hypertension
Ankara University
2016-2024
Pfizer (United Kingdom)
2024
Roche (Switzerland)
2024
AstraZeneca (Brazil)
2024
Weatherford College
2024
Pfizer (United States)
2024
Novartis (Switzerland)
2024
Kutahya Saglik Bilimleri Universitesi
2021
Hacettepe University
2015-2021
Sağlık Bilimleri Üniversitesi
2021
Low serum sodium affects cancer prognosis, but its impact on immunotherapy is unclear.
Introduction and aim To investigate the effect of prognostic nutritional index on treatment response survival in patients with metastatic renal cell cancer. Methods We retrospectively analyzed modalities; demographic, clinical pathological features 396 RCC index. Based median value, were grouped as having low high values. Kaplan-Meier method was used for analysis, Cox-regression analysis multivariate analysis. Results The overall 39 months (95% CI 26.1–51.8), 28 17.9–38) 7 4.7–9.2)...
Background To describe the prognostic value of neutrophil–lymphocyte ratio and its effect on survival in patients with advanced renal cell carcinoma. Methods We retrospectively analyzed 331 patients. The cut-off was specified as “3” which is mostly close—and also clinically easily applicable—to median level our study group. High group identified >3 (n = 160) low ≤3 163). Results A total (with 211 male 120 female) were enrolled to study. age 58. International Metastatic RCC Database...
Tumor lysis syndrome (TLS) is an important oncological emergency that usually observed with hematological malignancies and rarely solid tumors. It can be induced either by therapy or spontaneously. Radiotherapy-induced TLS has been reported in the literature. Here we present a patient diagnosis of metastatic prostate cancer chronic lymphocytic leukemia complicated during palliative radiotherapy. Tümör lizis sendromu sıklıkla hematolojik malignitelerde görülen, nadiren tümörlerde karşımıza...
Objective To evaluate prognostic factors associated with the use of ipilimumab in patients mucosal and uveal melanoma. Methods In this multicenter, retrospective study, 31 melanoma diagnosed between 2010 2017 were enrolled. Patients’ characteristics, metastatic disease sites, treatment before therapy, performance status, hemoglobin, lactate dehydrogenase levels, B-RAF c-kit mutation toxicity, survival data assessed for SPSS version 17 was used statistical analysis. Kaplan–Meier method The...
To define the role of 18F-flourodeoxyglucose (FDG) positron emission tomography (PET)/computed (CT) in detection bone marrow (BM) involvement patients with diffuse large B cell lymphoma (DLBCL).Fifty-four (mean age: 55.5 ± 18.3 years, 20 female and 34 male) DLBCL who underwent pretreatment 18F-FDG PET/CT were included to study. Focal or BM uptake that is higher than mediastinal blood pool was accepted as positive. After staging disease by CT PET/CT, all received R-CHOP treatment after...
Purpose Studies in the last decade show survival improvement with checkpoint blocker therapy patients metastatic malign melanoma. Our purpose was to define efficacy of ipilimumab according patient's baseline characteristics including absolute lymphocytes count. Methods We collected data 97 advanced melanoma treated (3 mg/kg, q3w) retrospectively. Log-rank test used analyze univariate effects (age, gender, sites, ECOG PS, type melanoma, lactic dehydrogenase levels, anemia, (L), neutrophils...
Introduction Ipilimumab is an anti-cytotoxic T lymphocyte antigen 4 (CTLA-4) antibody. has shown improvement in overall survival patients with advanced melanoma. Because ipilimumab activates the immune system against tumor, associated adverse events related to activation. Immune-associated side effects are frequently seen gastrointestinal and skin. Sweet’s syndrome (SS) uncommon inflammatory disorder. Some drugs or malignancy can cause SS. Only a few case reports have been reported of...
Kaposi sarcoma (KS) is a low-grade mesenchymal angioproliferative disease, mostly observed in immune compromised patients. KS encountered HIV-positive or organ transplant The drugs causing immunosuppression have also been associated with KS. Here, we present experience rituximab-based therapy.
Objective Fear of cancer recurrence (FCR) is an important psychological trauma associated with reduction in the quality life, disruptions level adjustment, emotional distress and anxiety. The purpose study was to evaluate impact patient–physician relationship on FCR. Methods designed as a multicentre survey study. survivors, who were under remission, evaluated structured questionnaires. Patient–physician (PPR) scale which higher scores indicate better FCR inventory used. Results Between...
To evaluate radiological and clinical features in metastatic anaplastic lymphoma kinase+ non-small cell lung cancer patients crizotinib efficacy different lines. This national, non-interventional, multicenter, retrospective archive screening study evaluated demographic, clinical, imaging features, treatment approaches treated between 2013-2017. Totally 367 (54.8% males, median age at diagnosis 54 years) were included. Of them, 45.4% smokers, 8.7% had a family history of cancer. On findings,...
To evaluate the incidence, clinical features, risk factors, and prognosis of central nervous system (CNS) involvement in patients with acute myeloid leukemia (AML).All AML who were admitted to Hacettepe University hospital between 2000 2021 evaluated. The medical records 548 cases retrospectively analyzed.The frequency CNS was 2.4% (n = 13) at diagnosis 4.6% 25) or during follow-up. Parenchymal seen 5 patients, leptomeningeal 11 patients. Three had both parenchymal involvements, 6 optic...
Adjuvant chemoradiotherapy (CRT) is the optimal management strategy in resectable gastric cancer. There a debate about efficacy of more aggressive CRT plus chemotherapy regimens adjuvant setting. This study aimed to compare docetaxel-cisplatin-fluorouracil (DCF) versus fluorouracil-folinic acid (FUFA) stage III
To evaluate the factors associated with Deep vein thrombosis (DVT) and pulmonary thromboembolism (PTE) in cancer patients. A total of 237 patients who underwent lower extremity venous Doppler Ultrasonography (USG) and/or computed tomography angiography (PCTA) were included. Patients' demographic characteristics; chemotherapy data; immobilization status; use central catheter; histories 4-day-long bed rest, surgery within last 6 months, long anesthesia for at least 2 hours, smoking, patients'...
Objectives Using a comprehensive dataset derived from the American Association for Cancer Research (AACR) Project Genomics, Evidence, Neoplasia, Information, and Exchange (GENIE), we sought to demonstrate genetic characteristics of esophageal squamous cell cancer (ESCC) adenocarcinoma (EAC). Methodology Data were extracted cBioPortal genomics (genie.cbioportal.org). Patients with EAC carcinoma selected. To compare categorical variables, either chi-square or Kruskal-Wallis test was used. The...
Objective: The purpose of this study is to investigate nurses' levels knowledge about port catheters (PCs), define factors effecting them and the subjects in which more education strategies should be developed. Patients Methods: A descriptive, cross-sectional was carried out cancer centers Turkey. Participants were evaluated with structured questionnaires assess PCs management PC related complications. questions designed evaluate their different subscales. Results: 363 nurses 7 4 cities...
Introduction: The efficacy and tolerability of Enzalutamide Abiraterone Acetate have been reported in elderly patients with metastatic castration resistant prostate cancer (mCRPC). However, there is no randomized study directly comparing antitumor effects between these 2 agents geriatric patients. We aimed to evaluate the (ENZA) (AA) as a first-line treatment mCRPC Materials methods: (≥75 years age) diagnosis treated ENZA or AA were included. impacts clinical parameters modalities on overall...