Hakan Akbulut

ORCID: 0009-0009-0015-2630
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About
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Research Areas
  • Cancer Treatment and Pharmacology
  • Lung Cancer Treatments and Mutations
  • HER2/EGFR in Cancer Research
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Metastasis and carcinoma case studies
  • Colorectal Cancer Screening and Detection
  • Sodium Intake and Health
  • Soft tissue tumor case studies
  • Colorectal Cancer Surgical Treatments
  • Frailty in Older Adults
  • Hormonal Regulation and Hypertension
  • Neuroblastoma Research and Treatments
  • Neutropenia and Cancer Infections
  • Electrolyte and hormonal disorders
  • Lymphoma Diagnosis and Treatment
  • Gastric Cancer Management and Outcomes
  • Occupational and environmental lung diseases

Ankara University
1995-2024

Aim: Identification of patient with increased risk cardiotoxicity would allow not only prevention and early diagnosis chemotherapy related but also administration optimal dose duration chemotherapy. Materials methods: Fiftytwo women HER2+ breast cancer treated trastuzumab were included in this study. Patients prospectively followed routine cardiac evaluation. Before after blood samples for NT-proBNP taken. Results: The median age was 48.5 year (range: 26–74). Hypertension obesity two most...

10.31768/2312-8852.2015.37(1):53-57 article EN Experimental Oncology 2015-03-22

Twenty-one consecutive patients with refractory or relapsed non-Hodgkin's lymphomas were treated a novel combination chemotherapy (MINE-BOP), comprising myelosuppressive (ifosfamide, mitoxantrone, etoposide) and non-myelosupressive (bleomycin, vincristine prednisone) drugs. Median age of the was 42 years all had intermediate high-grade lymphoma. Fifteen disease. All previously been one two regimens, containing anthracyclines. In cases duration between last MINE-BOP regimen shorter than 12...

10.3109/02841869509127208 article EN Acta Oncologica 1995-01-01

Based on the promising results of EAP (etoposide, doxorubicin, and cisplatin) combination, a phase II study modified combination was performed in patients with advanced gastric cancer to evaluate response, toxicity, survival.Fifty-two consecutive measurable or evaluable cancer, who had no prior therapy except surgery, were treated every 28 days etoposide 120 mg/m2/day, doxorubicin 25 cisplatin 40 mg/m2/day 1 8, intravenously. Forty-seven for response toxicity.Overall rate 40.5% (95% CI =...

10.1002/(sici)1096-9098(199704)64:4<318::aid-jso13>3.0.co;2-z article EN Journal of Surgical Oncology 1997-04-01
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