Tuğçe Kütük

ORCID: 0000-0003-0416-8612
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About
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Research Areas
  • Glioma Diagnosis and Treatment
  • Brain Metastases and Treatment
  • Advanced Radiotherapy Techniques
  • Medical Imaging Techniques and Applications
  • Radiomics and Machine Learning in Medical Imaging
  • Head and Neck Cancer Studies
  • Radiopharmaceutical Chemistry and Applications
  • Meningioma and schwannoma management
  • Lung Cancer Research Studies
  • Lung Cancer Diagnosis and Treatment
  • Lung Cancer Treatments and Mutations
  • Economic and Financial Impacts of Cancer
  • MRI in cancer diagnosis
  • Adrenal and Paraganglionic Tumors
  • Advances in Oncology and Radiotherapy
  • Oral health in cancer treatment
  • Global Cancer Incidence and Screening
  • Occupational and environmental lung diseases
  • Pleural and Pulmonary Diseases
  • Cancer Research and Treatments
  • Cancer-related cognitive impairment studies
  • Salivary Gland Disorders and Functions
  • Ocular Oncology and Treatments
  • Multiple and Secondary Primary Cancers
  • Renal cell carcinoma treatment

Baptist Hospital of Miami
2021-2025

Baptist Health South Florida
2021-2025

Ankara University
2015-2024

Moffitt Cancer Center
2020-2024

Malatya Devlet Hastanesi
2018-2023

Miami Heart Research Institute
2023

Florida International University
2023

Digital Health Cooperative Research Centre
2022

Digital China Health (China)
2022

Education and Research Institute
2021

Abstract Background Despite advances in our understanding of the molecular underpinnings meningioma progression and innovations systemic local treatments, recurrent meningiomas remain a substantial therapeutic challenge. The objective this systematic review meta-analysis is to provide historical baseline, contemporary analysis, propose “rate probable interest” inform future clinical trial design development on behalf RANO group. Methods PubMed, ClinicalTrials.gov, ASCOpubs databases were...

10.1093/neuonc/noaf009 article EN Neuro-Oncology 2025-01-14

Radiation therapy (RT) plays a crucial role in the treatment of head and neck cancers (HNCs). This paper emphasizes importance effective communication collaboration between radiation oncologists dental specialists HNC care pathway. It also provides an overview RT illustrates interdisciplinary these teams to optimize patient care, expedite treatment, prevent post-treatment oral complications. The methods utilized include thorough analysis existing research articles, case reports, clinical...

10.3390/curroncol31040155 article EN cc-by Current Oncology 2024-04-07

PURPOSE Adaptive radiotherapy accounts for interfractional anatomic changes. We hypothesize that changes in the gross tumor volumes identified during daily scans could be analyzed using delta-radiomics to predict disease progression events. evaluated whether an auxiliary data set improve prediction performance. MATERIALS AND METHODS 108 patients (n = 90 internal; n 18 external) who received ablative radiotherapy. The internal included 42 with adrenal cancer, 23 lung and 25 pancreatic...

10.1200/cci.24.00002 article EN JCO Clinical Cancer Informatics 2025-01-01

PURPOSE Survival for patients with melanoma has recently improved. The propensity of to metastasize the brain remains a common and serious feature this disease. purposes study were evaluate prognostic factors newly diagnosed metastases (MBMs) in large cohort treated modern multimodal therapies, compare those results prior eras, update Melanoma Graded Prognostic Assessment (GPA). METHODS Univariable multivariable (MVA) analyses treatments associated survival performed on 1,796 MBM between...

10.1200/jco-24-01351 article EN Journal of Clinical Oncology 2025-04-17

We compared the clinical outcomes of BM treated with mask immobilization zero-SM (i.e., zero-PTV) to standard frame SRS. Consecutive patients BM, 0.5−2.0 cm in maximal diameter, single-fraction SRS (22−24 Gy) during March 2019−February 2021 were included. Univariable and multivariable analysis performed using Kaplan−Meier method Cox proportional hazards regression. A total 150 453 met inclusion criteria. 129 (28.5%) lesions a 324 (71.5%) immobilization. Frame treatments associated higher...

10.3390/cancers14143392 article EN Cancers 2022-07-13

The objective of this study was to evaluate the impact time interval between planning imaging and stereotactic radiosurgery (SRS) delivery on tumor volumes spatial anatomic displacements brain metastases (BM).Consecutive patients diagnosed with BM treated SRS over a 3-year period were evaluated. Only who underwent an institutionally standardized diagnostic MRI (MRI-1) treatment (MRI-2) included. histology, inter-scan interval, lesion location, volume, diameter evaluated final diameter,...

10.1093/nop/npab047 article EN Neuro-Oncology Practice 2021-07-28

The objectives of this study were to evaluate the implementation, device usage rates, clinical outcomes, and treatment-related toxicities associated with TTFields pemetrexed plus platinum-based chemotherapy in patients unresectable MPM, outside initial trial results.Consecutive MPM enrolled onto an FDA-required HDE protocol from 2019 2021. All treated a protocol-defined regimen continuous (150 kHz) chemotherapy.Five enrolled. median number 4-week cycles was 5 (range: 2-7 cycles). Median...

10.3390/cancers14082020 article EN Cancers 2022-04-16

While dose escalation is associated with improved local control (LC) for adrenal gland metastases (AGMs), the proximity of gastrointestinal (GI) organs-at-risk (OARs) limits that can be safely prescribed via CT-based stereotactic body radiation therapy (SBRT). The advantages magnetic resonance-guided SBRT (MRgSBRT), including tumor tracking and online plan adaptation, facilitate safe escalation.

10.1016/j.ctro.2023.100719 article EN cc-by-nc-nd Clinical and Translational Radiation Oncology 2024-01-05

Patients with stage III non-small-cell lung cancer (NSCLC) treated chemoradiotherapy (CRT) in low- and middle-income countries (LMIC) continue to have a poor prognosis. It is known that FDG PET/CT improves staging, treatment selection target volume delineation (TVD), although its use has grown rapidly, it still not widely available LMIC. CRT often used as sequential treatment, but be more effective when given concurrently. The aim of the PERTAIN study was assess impact introducing...

10.1007/s00259-019-04421-5 article EN cc-by European Journal of Nuclear Medicine and Molecular Imaging 2019-07-31

10.1007/s40257-020-00572-6 article EN American Journal of Clinical Dermatology 2020-12-23

Randomized data show a survival benefit of stereotactic ablative body radiation therapy in selected patients with oligometastases (OM). Stereotactic magnetic resonance guided adaptive (SMART) may facilitate the delivery dose for OM lesions, especially those adjacent to historically dose-limiting organs at risk, where conventional approaches preclude dosing.The RSSearch Registry was queried (1-5 metastatic lesions) treated SMART. Freedom from local progression (FFLP), freedom distant (FFDP),...

10.1016/j.adro.2022.100978 article EN cc-by-nc-nd Advances in Radiation Oncology 2022-04-25

Purpose To report the utilization of radiation therapy in Syrian refugee patients with prostate cancer residing Turkey. Methods and materials A multi-institutional retrospective review including 14 centers Turkey was conducted to include 137 treated (RT). Toxicity data scored using National Cancer Institute Common Terminology Criteria for Adverse Events version 3.0. Noncompliance defined as a patient missing two or more scheduled RT appointments. Results Advanced disease, stage III IV,...

10.3389/fpubh.2023.1172864 article EN cc-by Frontiers in Public Health 2023-05-31

Image-based biomarkers could have translational implications by characterizing tumor behavior of lung cancers diagnosed during cancer screening. In this study, peritumoral and intratumoral radiomics volume doubling time (VDT) were used to identify high-risk subsets patients in screening that are associated with poor survival outcomes.Data images acquired from the National Lung Screening Trial. VDT was calculated between two consequent intervals approximately 1 year apart; extracted baseline...

10.3233/cbm-210194 article EN Cancer Biomarkers 2022-04-18

We evaluated the effect of lesion number and volume for brain metastasis treated with SRS using GammaKnife® ICON™ (GK) CyberKnife® M6™ (CK). Four sets sizes (<5 mm, 5–10 >10–15 >15 mm) were contoured prescribed a dose 20 Gy/1 fraction. The lesions was increased until threshold mean 8 Gy reached; then individually optimized to achieve maximum conformity. Across GK plans, linearly proportional total GTV all sizes. numbers needed reach this 177, 57, 29, 10 each size group,...

10.3390/cancers15030780 article EN Cancers 2023-01-27

Tubarial glands are a new organ at risk for head and neck cancer radiation therapy (RT). We aimed to study the feasibility of sparing them using intensity-modulated (IMRT).

10.1002/hed.27791 article EN Head & Neck 2024-05-15
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