A5064029387- Colorectal Cancer Treatments and Studies
- Cancer Treatment and Pharmacology
- Lung Cancer Treatments and Mutations
- Chemotherapy-related skin toxicity
- Lung Cancer Research Studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Immunotherapy and Immune Responses
- Neuroblastoma Research and Treatments
- Monoclonal and Polyclonal Antibodies Research
- Brain Metastases and Treatment
- HER2/EGFR in Cancer Research
- PI3K/AKT/mTOR signaling in cancer
- Neuroendocrine Tumor Research Advances
- Chronic Lymphocytic Leukemia Research
- Erythropoietin and Anemia Treatment
- Cancer Immunotherapy and Biomarkers
- Advances in Oncology and Radiotherapy
- Melanoma and MAPK Pathways
- Herbal Medicine Research Studies
- Protein Degradation and Inhibitors
- Advanced Radiotherapy Techniques
- Cancer, Lipids, and Metabolism
- Lung Cancer Diagnosis and Treatment
- Advanced MRI Techniques and Applications
- Uterine Myomas and Treatments
Bursa Uludağ Üni̇versi̇tesi̇
2017-2024
Balıkesir University
2018-2023
Creative Research Enterprises (United States)
2017-2018
(1) Background: Metastatic L-type sarcomas (liposarcoma and leiomyosarcoma) are rare have a poor prognosis. Trabectedin is an effective agent that can be used after anthracyclines. This study was designed to evaluate the real-life effectiveness safety of trabectedin. (2) Methods: A retrospective multicenter conducted on patients who were treated with trabectedin for metastatic at ten tertiary oncology centers between 2015 2023. The objective response rate (ORR), disease control (DCR), time...
The prognosis of patients with advanced HCC can vary widely depending on factors such as the stage cancer, patient's overall health, and treatment regimens. This study aimed to investigate survival outcomes associated in hepatocellular carcinoma (HCC). In this retrospective study, data from 23 medical oncology clinics were analyzed. Progression-free (PFS) (OS) values estimated using Kaplan–Meier method. Prognostic which identified univariate analysis subsequently evaluated a multivariate...
NUT midline carcinoma (NMC) is an aggressive malignant neoplasm arising from structures. Although it classified as a rare disease, the pathological nonspecific appearance undifferentiated/poorly differentiated and difficulty in making definitive diagnosis are probably reasons for underdiagnosis; disease thought to be more prevalent. There no standard treatment disease. The shows poor response chemotherapy radiotherapy, patients’ survival poor. We present case of sinonasal NMC treated with...
The aim of this study was to examine the value an additional atropine injection in patients who do not achieve adequate heart rate during dobutamine infusion for myocardial perfusion SPET (single photon emission tomography). Patients undergoing failed > or = 85% their age-predicted maximal at end (D protocol) had a second on separate day with addition + A protocol). Twenty-nine were studied. 201Tl used 27 and 99Tc(m)-MIBI two patients. All underwent coronary angiography significant artery...
Introduction Hyperprogression is a specific type of response seen with immunotherapy that observed in all malignancies frequency 9% - 29%, characterized by rapid increase tumor burden. Many possible related factors and markers have been evaluated but clinical or laboratory parameter associated hyperprogression has not yet established. For renal cell carcinoma, hypercalcemia known to be poor prognostic factor it linked hyperprogression. Case report We retrospectively 52 patients diagnosed...
Objective: This study aimed to evaluate radiotherapy (RT) doses, RT effects on neurocognitive functions, and possible factors that may affect recurrence or death in patients with glioblastoma multiforme (GBM). Methods:The data of 21 GBM were retrospectively analyzed.RT treatment plans doses hippocampus ipsilateral contralateral recorded.The Mini-Mental State Examination (MMSE) is used assess functions.The time death, if any, the was recorded.Factors such as gender, age, patient performance...
Thrombocytopenia is a characteristic adverse event of trastuzumab emtansine (T-DM1), one the essential treatment options for human epithelial growth factor receptor 2 (HER2)-positive breast cancer. The present study investigated predictive value thrombocytopenia time-to-treatment discontinuation (TTD) in patients receiving T-DM1 advanced-stage HER2-positive observational enrolled 138 who received at six oncology centers from January 2016 to December 2021. Univariate and multivariate Cox...
Background: In non-small cell lung cancer (NSCLC), immunotherapy is a treatment option in patients without targetable mutations second and later lines. Nevertheless, there no validated test that can predict response.
 Material Methods: Our study aimed to investigate the effect of radiotherapy (RT) on survival with NSCLC receiving after first-line chemotherapy. Twenty-five diagnosed received at least one previous chemotherapy line were included our study.
 Results: The median age...
ÖZETKlasik kemoterapötik ilaçlar hücre siklusunda arrest, replikasyonunun durdurulması ve apopitoz indüksiyonu ile etki gösterir
Chemotherapy is controversial in non‑metastatic typical carcinoid (TC) tumors. Therefore, it was aimed to evaluate the impact of platin‑based chemotherapy on survival patients with lung TC. The medical records who underwent surgical resection for TC from 2002 2020 at our institution were retrospectively reviewed. Multivariate regression analysis performed and prognostic factors disease‑free (DFS) 72 patients. pathological stages as follows: 73.6% stage I, 15.3% II 11.1% III. A total 5 (6.9%)...
Objectives: Carcinoid tumors are rare neuroendocrine neoplasms of the lung. Although typical and atypical carcinoids have different clinical courses, most studies in literature evaluate them together. Therefore, we aimed to investigate prognostic factors patients with carcinoids, excluding carcinoids. Methods: We included 32 according WHO 2021 criteria admitted Uludag University Hospital. retrospectively extracted clinicopathological characteristics from electronic medical records. The...
Kronik böbrek hastalığı (KBH) 3 aydan uzun süren, böbrekte işlevsel ya da yapısal bozukluk ve/veya glomerüler filtrasyon hızında azalma olmasıdır. Hastanede edinilmiş anemi (HEA), hastaneye yatış sonrası hastalarda etyolojik bir neden olmaksızın gelişmesidir. İyatrojenik geliştiği düşünülmektedir. Çalışmamızda KBH tanısıyla hasta-neye yatırılan HEA prevalansını ve etki eden faktörleri saptamayı amaçladık. Mart- Eylül 2014 arasında, 18 yaş üzerine, tanılı, nefroloji servisine yatışı yapılan...
Amaç: Kanser, psikolojik sorunlara da sebep olan bir hastalıktır. Kanser hastalarında uyku bozukluğu, depresyon, anksiyete sık görülmektedir. Bu çalışmada, diğer kanser türlerine göre kür sağlanma olasılığı daha yüksek erken evre meme kanseri tanılı, hormonoterapi tedavisi almakta ya tedavisiz izlemde hastalarda sıklığının belirlenmesini amaçladık. Gereç ve Yöntemler: Çalışma poliklinik ortamında, Pittsburgh Uyku Kalite İndeksi (PUKİ), Uykusuzluk Şiddeti (UŞİ), Hastane Anksiyete Depresyon...
Lokal ileri evre rektum kanseri tanısıyla, radyoterapi (RT) ile eş zamanlı 5-florourasil (5-FU) /kapesitabin uygulanan hastaların 10 yıllık sağkalım sonuçlarını ve sağkalıma etki eden faktörleri incelemeyi amaçladık. Mart 2004-Ocak 2007 arasında Radyoterapi Merkezi’nde 5-florourasil/kapesitabin lokal adenokarsinomu tanılı 81 hasta (55 5-FU, 26 kapesitabin) retrospektif değerlendirildi. Hastaların nüks metastaz durumu yaş, T evresi, N patoloji, müsin komponent varlığı, vasküler invazyon,...
Endometrium kanseri (EK) gelişmiş ülkelerde en sık görülen jinekolojik kanserdir. Obezite önemli risk faktörü olarak kabul edilmektedir. kanserleri içerisinde alt tip endometrioid endometrial karsinomdur (EEK). Çalışmamızda metastatik EEK hastalarının demografik ve klinikopatolojik özelliklerini, kullanılan tedavi yöntemlerinin sağ kalıma etkisini incelemeyi amaçladık. Hastaların medyan yaşı 58 (39,4-81,9) idi. On altı hastanın hastaneye başvuru şikayeti vajinal kanamaydı. Medyan takip...