A5051520275- Thyroid Disorders and Treatments
- Pituitary Gland Disorders and Treatments
- Thyroid Cancer Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Diabetes and associated disorders
- Electrolyte and hormonal disorders
- Neuroblastoma Research and Treatments
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Growth Hormone and Insulin-like Growth Factors
- Diet and metabolism studies
- Muscle and Compartmental Disorders
- Ion channel regulation and function
- Tracheal and airway disorders
- Myasthenia Gravis and Thymoma
- PI3K/AKT/mTOR signaling in cancer
- Ophthalmology and Eye Disorders
- Bone health and treatments
- Neurological and metabolic disorders
- Diabetic Foot Ulcer Assessment and Management
- Protein Tyrosine Phosphatases
- Adrenal Hormones and Disorders
- Pharmacology and Obesity Treatment
- Hormonal and reproductive studies
- Renal function and acid-base balance
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
Kent Hastanesi
2021
Necmettin Erbakan University
2012-2015
Istanbul Yeni Yüzyıl University
2015
Selçuk University
2005-2013
Weatherford College
2009
Akdeniz University
2002-2005
KTO Karatay University
2004
Ankara University
1999
Thyroid dysfunction may cause musculoskeletal symptoms. We have evaluated the prevalence of adhesive capsulitis, Dupuytren's contracture, trigger finger, limited joint mobility and carpal tunnel syndrome in a series patients with various thyroid diseases differing levels function.Patients euthyroid (diffuse and/or nodular) goitre, Hashimoto's thyroiditis, Graves' disease, toxic nodular diffuse goitre who had partial thyroidectomy were included study (n = 137). Neurological examinations...
Familial isolated pituitary adenoma (FIPA) due to aryl hydrocarbon receptor interacting protein (AIP) gene mutations is an autosomal dominant disease with incomplete penetrance. Clinical screening of apparently unaffected AIP mutation (AIPmut) carriers could identify previously unrecognized disease. To determine the mutational status FIPA and young patients, analyzing their clinical characteristics, perform AIPmut carrier family members. This was observational, longitudinal study conducted...
Raf/MEK/ERK and phosphatidylinositol 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) cascades are key signalling pathways interacting with each other to regulate cell growth tumourigenesis. We have previously shown B-Raf Akt overexpression and/or overactivation in pituitary adenomas. The aim this study is assess the expression their downstream components (MEK1/2, ERK1/2, mTOR, TSC2, p70S6K) effectors (c-MYC CYCLIN D1). studied tissue from 16 non-functioning adenomas (NFPAs), six...
Abstract Context Germline mutations in the aryl hydrocarbon receptor-interacting protein (AIP) gene are responsible for a subset of familial isolated pituitary adenoma (FIPA) cases and sporadic neuroendocrine tumors (PitNETs). Objective To compare prospectively diagnosed AIP mutation-positive (AIPmut) PitNET patients with clinically presenting to clinical characteristics AIPmut AIPneg patients. Design 12-year prospective, observational study. Participants & Setting We studied probands...
Sibutramine and orlistat are currently used for weight loss. We aimed to investigate the effect of sibutramine combination therapy in treatment obese women.Study population consisted 89 women who had a body mass index > or = 30 kg/m2, were normotensive, normal glucose tolerance. All patients placed on diet which contained fat approximately 30% total calorie intake was designed cause an energy deficit 2.51-3.56 megajoule/day. At first month (baseline), all randomly divided into three groups:...
Thyroid malignancy detected incidentally in patients who are operated for thyrotoxicosis has been reported at different rates. The aim of this study was to investigate the rate incidental thyroid carcinoma thyrotoxic managed with surgery our institution.Of 375 had between years 1997-2004, 70.7% were females and 29.3% males. Among 65.3% (n=245) toxic multinodular goiter (TMG), 16.8% (n=63) adenoma (TA) 17.9% (n=67) Graves' disease.Twenty-six (6.9%) all carcinoma. Eighteen (7.3%) TMG, 4 (6.3%)...
Vascular endothelial growth factor (VEGF) is a major regulator of angiogenesis and may be produced by some cancer cells. Several recent reports have documented that increased expression VEGF associated with risk recurrence or decreased recurrence‐free survival in papillary thyroid cancers (PTC). The aims this study were to determine whether immunohistochemical related local distant PTC evaluate the relationship between hypervascularization carcinomas. was examined immunohistochemically 48...
Thyroid hormone has been shown to control retinal cone opsin expression, the protein of color vision, in adult rodents.The aim this study was evaluate effect hypothyroidism on contrast sensitivity overt hypothyroid patients.Thirty-eight (31 females, 7 males) subjects and 20 euthyroid (16 4 controls were studied prospectively. Color vision examination performed by Chromatest, a software program analyzing tritan (blue-yellow) threshold (tritan CCT) protan (red-green) (protan CCT). analyses...
Thyroid hemiagenesis is a rare congenital anomaly in which one of the thyroid lobes with or without isthmus fails to develop. Here we present woman patient hemiagenesis, Graves' disease and ophthalmopathy nodular goiter. Fine needle aspiration biopsy dominant nodule was suspicious malignancy. The referred for surgery total thyroidectomy. Histopathological examination surgical material revealed benign features. case confirms that, although rare, number concomitant disorders can exist single...
Serum C-X-C motif chemokine 10 (CXCL10) levels have been shown to be elevated in autoimmune thyroid diseases (AITD). This study sought determine whether newly diagnosed AITD patients with neuromuscular findings had higher of CXCL10 than those without manifestations.A total 80 were recruited the study, which included treatment-naive hypothyroid Hashimoto's thyroiditis (n = 19) and hyperthyroid Graves' disease (GD; n 21), euthyroid autoantibody-positive 20) -negative patients.All underwent a...