- Diabetes Management and Research
- Diabetes and associated disorders
- Pituitary Gland Disorders and Treatments
- Diet and metabolism studies
- Adipokines, Inflammation, and Metabolic Diseases
- Thyroid Disorders and Treatments
- Diabetes Treatment and Management
- Regulation of Appetite and Obesity
- Growth Hormone and Insulin-like Growth Factors
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetic Foot Ulcer Assessment and Management
- Pancreatic function and diabetes
- Thyroid Cancer Diagnosis and Treatment
- Nutrition and Health in Aging
- Ophthalmology and Eye Disorders
- Gestational Diabetes Research and Management
- Pain Mechanisms and Treatments
- Adipose Tissue and Metabolism
- Diet, Metabolism, and Disease
- Glaucoma and retinal disorders
- Parathyroid Disorders and Treatments
- Metabolism, Diabetes, and Cancer
- Biochemical effects in animals
- Dietary Effects on Health
- Botulinum Toxin and Related Neurological Disorders
Gazi University
2013-2024
Hôpital Bichat-Claude-Bernard
2023
Université Claude Bernard Lyon 1
2023
Assistance Publique – Hôpitaux de Paris
2023
Cliniques du Sud Luxembourg
2023
Homi Bhabha National Institute
2023
Tata Memorial Hospital
2023
Azienda Ospedaliero-Universitaria di Modena
2023
Polytechnic of Međimurje in Čakovec
2023
Sahlgrenska University Hospital
2023
Background: Free radical-mediated oxidative stress has been implicated in the etiopathogenesis of several autoimmune disorders. Also, there is growing evidence supporting role reactive oxygen species pathogenesis thyroid The aim this study was to investigate influence hypothyroidism, hyperthyroidism, and their treatments on metabolic state stress, antioxidant status markers.
Adiponectin and tumor necrosis factor-α (TNF-α) have been implicated in insulin resistance diabetes mellitus (DM). In the present study we investigated levels of adiponectin TNF-α their relationships with each other metabolic factors women gestational DM (GDM). Thirty-four pregnant GDM 31 normal glucose tolerance (NGT) were included study. Plasma lower than NGT (36.9 ± 6.7 vs. 61.3 13.0 ng/ml, p = 0.028). Serum increased compared (20.5 2.4 14.0 1.5 pg/ml, 0.042). After adjustment for...
Commonly used immunoassays are not free from interference, which can be a confounder in the interpretation of test results. We present case with extremely high multiple hormone levels due to such interference.A 33-year-old woman no specific symptoms had markedly elevated TSH normal T4 and T3 levels. Repeated measurements revealed discordantly TSH, ACTH, FSH, PTH, IGF-1, prolactin, β-human chorionic gonadotropin, calcitonin without associated clinical pictures. The were repeated same patient...
The aim of the present study was to evaluate insulin resistance (IR), glucose tolerance status and cardiovascular risk factors in first degree relatives patients with polycystic ovary syndrome (PCOS).A total 120 family members [Mothers(PCOS) (n = 40), Fathers(PCOS) 38), Sisters(PCOS) 25) Brothers(PCOS) 17)] 55 PCOS 75 unrelated healthy control subjects without a history diabetes or (four age- weight-matched subgroups, i.e. Control(Mothers), Control(Fathers), Control(Sisters)...
Aim: To investigate the effect of diabetes mellitus on Achilles tendon, which may contribute to long-term complications in foot-ankle complex and factors relating its thickening.
The autosomal dominant form of familial neurohypophyseal diabetes insipidus (adFNDI) has been linked to 40 different mutations the gene encoding vasopressin-neurophysin II (AVP-NPII) precursor. All these have located in either signal peptide or neurophysin moiety. We now report a three-generation Turkish kindred which severe adFNDI cosegregates with novel missense mutation part AVP-NPII AVP This (T→C at position 285 genomic sequence) was found only one allele and predicts substitution...
<i>Purpose:</i> To evaluate the effect of blood glucose (BG) regulation on retinal nerve fiber layer (RNFL) in diabetic patients by using a scanning laser polarimeter (NFA-GDx). <i>Methods:</i> We prospectively assessed RNFL thickness and an age-matched control group. Patients without retinopathy, with BG >250 mg/dl, HbA1c >8%, fructosamine >285 µmol/l triglyceride >200 mg/dl were included study. assessment was performed before after metabolic diabetes....
Hashimoto's thyroiditis is an autoimmune thyroid disorder. Lymphocytic colitis and collagenous are characterized by diarrhea with normal endoscopic findings. Autoimmune disorders common in lymphocytic colitis. The aim of this study was to investigate the incidence patients thyroiditis.Fifty well-documented were included. Twenty nonulcer dyspepsia served as a control group. Five 50 reported intermittent diarrhea, whereas no had All group underwent total colonoscopy, multiple colonoscopic...
Objective: Hypothyroidism is associated with changes in appetite and body weight. Ghrelin an orexigenic peptide, it stimulates increases food intake. However, the potential relationship between circulating ghrelin levels, hypothyroidism, thyroid antibodies has not been adequately studied. Design: Forty-seven patients hypothyroidism due to Hashimoto's thyroiditis 48 euthyroid subjects were enrolled study. Thyroid hormones antibodies, insulin, glucose, lipid parameters measured all subjects....
We aimed to investigate the relationship between serum osteoprotegerin (OPG) level and glycemic control, lipids, renal function, microalbuminuria, insulin resistance markers of atherosclerosis including C-reactive protein (CRP), fibrinogen erythrocyte sedimentation rate (ESR) in patients with type 2 diabetes mellitus (DM). A total 166 (99 women 67 men) DM were recruited study. Serum OPG was higher poorly controlled diabetic (HbA(1c) ≥ 7%) than well-controlled < [4.0 (3.6-5.0) 3.5 (2.9-4.4)...
Aims . Growth Differentiation Factor-15 (GDF-15) has been suggested as one of the regulators hepcidin, an important regulatory peptide for iron deposition. Current data is conflicting about relationship between hepcidin and disorders glucose metabolism. We aimed to investigate serum GDF-15 concentrations their associations with each other, in nonanemic subjects impaired tolerance (IGT) comparison normal (NGT). Methods Thirty-seven IGT 32 control NGT, who were age-, gender-, body mass index-...
Purpose To evaluate the changes in intraocular pressure (IOP), corneal thickness (CT), and retinal nerve fiber layer (RNFLT) patients with hypothyroidism before after treatment. Methods A complete ophthalmic examination including visual acuity, IOP, anterior segment, fundus together CT RNFLT measurements were performed for each patient newly diagnosed hypothyroidism, at initial diagnosis third ninth months of L-thyroxine Wilcoxon signed rank test Spearman's correlation used statistical...
Targeting better glycated hemoglobin (HbA1c) and blood pressure (BP) goals may endanger older adults with type 2 diabetes mellitus (T2DM). Overtreatment of T2DM hypertension is a trending issue, although undertreatment still common. We investigated the rates predictors overtreatment glycemia BP in physicians' attitudes to deintensify or intensify treatment. Data from (≥ 65 years) enrolled large nationwide survey 2017 across Turkey were analyzed. was defined as HbA1c < 6.5% plus use ≥ oral...
Recent studies have revealed that circulating ghrelin levels seem to play a role in energy homeostasis. The effect of hyperthyroidism on is not fully known.Serum and its relationship with insulin resistance were evaluated 48 patients 43 euthyroid healthy controls. Thyroid hormones, insulin, glucose, lipid parameters measured all subjects. Insulin sensitivity was determined using the homeostasis model assessment.Serum significantly decreased hyperthyroid than controls (32.5 +/- 23.3 vs. 54.1...
Aim. This study was designed to examine the relationship between Pro12Ala polymorphism of peroxisome proliferator-activated receptor-γ (PPAR-γ) gene and insulin resistance (IR) in first-degree relatives subjects with polycystic ovary syndrome (PCOS).Materials methods. One hundred twenty family members 55 patients PCOS 80 unrelated healthy control without a history diabetes or were studied. IR assessed by homeostatic model assessment (HOMA-IR) area under curve (AUC) for during an oral glucose...