Mehmet Muhittin Yalçın

ORCID: 0000-0002-1041-6881
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About
Contact & Profiles
Research Areas
  • Thyroid Cancer Diagnosis and Treatment
  • Pituitary Gland Disorders and Treatments
  • Thyroid Disorders and Treatments
  • Growth Hormone and Insulin-like Growth Factors
  • Diabetes Management and Research
  • Stress Responses and Cortisol
  • Hormonal Regulation and Hypertension
  • Adrenal and Paraganglionic Tumors
  • Thyroid and Parathyroid Surgery
  • Head and Neck Anomalies
  • Adrenal Hormones and Disorders
  • Diet and metabolism studies
  • Nutrition and Health in Aging
  • Adipose Tissue and Metabolism
  • Parathyroid Disorders and Treatments
  • Adipokines, Inflammation, and Metabolic Diseases
  • Kruppel-like factors research
  • Diabetes and associated disorders
  • Apelin-related biomedical research
  • Blood disorders and treatments
  • Pancreatitis Pathology and Treatment
  • Liver Disease Diagnosis and Treatment
  • Radiation Dose and Imaging
  • Pancreatic function and diabetes
  • Gestational Diabetes Research and Management

Gazi University
2016-2025

Süleyman Demirel University
2024

Sahlgrenska University Hospital
2023

Hôpital Bichat-Claude-Bernard
2023

Université Claude Bernard Lyon 1
2023

Assistance Publique – Hôpitaux de Paris
2023

Cliniques du Sud Luxembourg
2023

Homi Bhabha National Institute
2023

Tata Memorial Hospital
2023

Azienda Ospedaliero-Universitaria di Modena
2023

Commonly used immunoassays are not free from interference, which can be a confounder in the interpretation of test results. We present case with extremely high multiple hormone levels due to such interference.A 33-year-old woman no specific symptoms had markedly elevated TSH normal T4 and T3 levels. Repeated measurements revealed discordantly TSH, ACTH, FSH, PTH, IGF-1, prolactin, β-human chorionic gonadotropin, calcitonin without associated clinical pictures. The were repeated same patient...

10.1210/jc.2014-4023 article EN The Journal of Clinical Endocrinology & Metabolism 2015-04-21

Recent studies imply that euthyroid Hashimoto's thyroiditis (HT) might be related with impaired HRQoL, depression and anxiety. Ninety three patients HT 31 age- gender-matched control subjects were enrolled into this study. SF-36 questionnaire, Beck Depression Inventory Anxiety tests used for evaluating scores higher in compared to (7.5 (4.0-14.75) vs. 5.0 (2.25-9.0), p=0.008). Questionnaire also than controls (9.50 (5.0-17.0) (2.0-11.75), p=0.021). In questionnaire; physical functioning...

10.1507/endocrj.ej16-0418 article EN Endocrine Journal 2017-01-01

Adults with type 1 diabetes (T1D) are reported to be at higher risk for clinical eating disorders (ED) and other disordered behaviors (DEB) than their peers without diabetes. On the hand, there is insufficient data on DEB in adults 2 (T2D). Our study aimed investigate prevalence of patients T1D T2D intensive insulin therapy followed our outpatient clinic. Diabetes Eating Problem Survey-Revised (DEPS-R), electronically delivered who were an regimen up clinic center evaluation DEB. A total 120...

10.1186/s40337-025-01188-z article EN cc-by-nc-nd Journal of Eating Disorders 2025-01-21

Abstract Introduction X-linked adrenoleukodystrophy (X-ALD; OMIM:300100) is a progressive neurodegenerative disorder resulting from congenital defect in the ABCD1 gene, which encodes protein (ALDP). Deficiency of ALDP leads to impaired peroxisomal β-oxidation very long chain fatty acids (VLCFAs), causing their accumulation nervous system, testes, and adrenal cortex. Clinical Case A 20-year-old male patient was referred neurology clinic with speech disorder, coordination while eating,...

10.1210/jcemcr/luae218.003 article EN cc-by-nc-nd JCEM Case Reports 2025-01-01

Backgrounds Serum thyroglobulin immunometric assays (sTg) are crucial for monitoring differentiated thyroid cancer (DTC) treatment. However, challenges such as anti-thyroglobulin autoantibodies (TgAb) and assay variability hinder evaluations. This study assessed four sTg methods—three second-generation (Architect, Access, Elecsys) one first-generation (Immulite)—following Clinical Laboratory Standards Institute (CLSI) American Thyroid Association (ATA) guidelines.

10.1080/00365513.2025.2479037 article EN Scandinavian Journal of Clinical and Laboratory Investigation 2025-03-17

We investigated the clinical course and mortality of acute respiratory distress syndrome (ARDS) in patients with hematological malignancies.Sixty-eight malignancies ARDS admitted to medical intensive care unit (ICU) a university hospital were analyzed semi-prospectively study.The most common etiology was pneumonia. The ratio partial pressure oxygen arterial blood fractional concentration inspired (PO2/FiO2) 104 (74-165). Ten (15%) received non-invasive mechanical ventilation (NIV), 21 (31%)...

10.1179/1607845412y.0000000038 article EN Hematology 2013-01-16

Aims . Growth Differentiation Factor-15 (GDF-15) has been suggested as one of the regulators hepcidin, an important regulatory peptide for iron deposition. Current data is conflicting about relationship between hepcidin and disorders glucose metabolism. We aimed to investigate serum GDF-15 concentrations their associations with each other, in nonanemic subjects impaired tolerance (IGT) comparison normal (NGT). Methods Thirty-seven IGT 32 control NGT, who were age-, gender-, body mass index-...

10.1155/2016/1240843 article EN cc-by Journal of Diabetes Research 2016-01-01

To investigate the association between papillary thyroid cancer (PTC) and Hashimoto's thyroiditis (HT).This study is a retrospective that conducted during 7 consecutive years with median 119.5 months follow-up.Patients who underwent thyroidectomy in Dokuz Eylül University Hospital were included. Patients' demographics, biochemical, radiological, pathological results retrospectively assessed.Four hundred sixty nine patients evaluated. Among 469 thyroidectomy, 132 (28.1%) malignant, while 182...

10.4183/aeb.2022.74 article EN Acta Endocrinologica (Bucharest) 2022-01-01

Thyroglobulin (Tg) assessment in the needle washout after fine-needle aspiration biopsy (FNAB) of a suspicious neck lymph node (LN) is known to improve diagnostic accuracy patients with papillary thyroid cancer (PTC). However, there still controversy on best cut-off levels for FNAB-Tg and whether thyroglobulin antibody (TgAb) positivity affects FNAB-Tg. The objectives this study were determine (i) power different cut-offs (ii) if serum TgAb(+) negatively evaluation.This was retrospective...

10.3109/07435800.2016.1141936 article EN Endocrine Research 2016-02-23

In this study, the presence of aminoglycoside-modifying enzyme (AME) and virulence factor genes were investigated in previously isolated 32 high-level aminoglycoside-resistant (HLAR) Enterococcus strains from retail chicken meat Turkey. At least one AME-encoding gene was detected HLAR enterococci by polymerase chain reaction (PCR). The ant(6ʹ)-Ia identified as most prevalent (87.5%, 28/32) AME gene. aph(3ʹ)-IIIa (78.13%, 25/32), ant(4ʹ)-Ia (68.75%, 22/32), aph(2ʹʹ)-Ib (62.5%, 20/32),...

10.12681/jhvms.30850 article EN cc-by-nc Journal of the Hellenic Veterinary Medical Society 2024-01-18

Objective: There may be an association between hyperprolactinemia and autoimmune diseases, possibly because of the immunostimulatory effect prolactin.The aim this study was to investigate prevalence thyroid non-thyroid serum B-cell activating factor (BAFF), proliferation-inducing ligand (APRIL) levels as indicators increased autoimmunity, quality life, depression, anxiety in patients with prolactinoma.Methods: Fifty-six premenopausal women prolactinoma 50 healthy were included...

10.12996/gmj.galenos.2023.3597 article EN cc-by Gazi Medical Journal 2024-01-01

Parathyroid hormone (PTH) interacts with components of the gut microbiota to exert its bone-regulating effects. This study aimed investigate microbial composition in patients primary hyperparathyroidism (PHPT). Nine PHPT and nine age-sex body mass index-matched healthy controls were included. Gut was assessed using 16S rRNA gene amplicon sequencing both groups at baseline 1 month after parathyroidectomy group. Data imported into QIIME-2 R packages used for microbiome analysis. Alpha beta...

10.1177/10815589241251695 article EN Journal of Investigative Medicine 2024-04-20

Abstract Although PSMA-targeted PET imaging is predominantly used for prostate carcinoma (PC), it has also been reported thyroid (TC). A 77-year-old man had a liver metastasectomy poorly differentiated TC, which elevated 18 F-FDG uptake. Two years later, he was diagnosed with acinar-type modified Gleason score of 7 (3 + 4) PC. Four metastatic lesions that no radioactive iodine and avidity. These were 68 Ga-PSMA avid, the biopsy confirmed TC metastasis. This case emphasizes importance...

10.1097/rlu.0000000000005299 article EN Clinical Nuclear Medicine 2024-06-03

Abstract Context The impact of abnormal cortisol secretion on cognitive functions in patients with mild autonomous (MACS) remains uncertain. Objective To assess functions, determine serum brain-derived neurotrophic factor (BDNF) concentration MACS, and investigate the association between subdomains BDNF. Methods We prospectively recruited 84 participants—28 28 nonfunctional adrenal adenoma (NFAA), control subjects matched for age, gender, body mass index (BMI), visceral adiposity,...

10.1093/ejendo/lvae070 article EN cc-by-nc European Journal of Endocrinology 2024-06-25
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