Ayşe Dursun

ORCID: 0000-0002-2591-0487
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Research Areas
  • Gastric Cancer Management and Outcomes
  • Helicobacter pylori-related gastroenterology studies
  • Gastrointestinal disorders and treatments
  • Sarcoma Diagnosis and Treatment
  • Gastrointestinal Tumor Research and Treatment
  • Microscopic Colitis
  • Colorectal Cancer Surgical Treatments
  • Angiogenesis and VEGF in Cancer
  • Inflammatory mediators and NSAID effects
  • Metastasis and carcinoma case studies
  • Inflammatory Bowel Disease
  • Colorectal and Anal Carcinomas
  • Cancer-related Molecular Pathways
  • Soft tissue tumor case studies
  • Cancer Diagnosis and Treatment
  • Cancer Research and Treatments
  • HER2/EGFR in Cancer Research
  • Estrogen and related hormone effects
  • Genetic factors in colorectal cancer
  • Celiac Disease Research and Management
  • Effects of Radiation Exposure
  • Eosinophilic Esophagitis
  • Neurofibromatosis and Schwannoma Cases
  • Breast Lesions and Carcinomas
  • Cancer, Stress, Anesthesia, and Immune Response

Gazi University
2011-2024

Bezmiâlem Vakıf Üniversitesi
2023-2024

Turkish Society of Hematology
2005

Abstract Background: Recent studies indicate a potential role of Saccharomyces boulardii in the prevention Helicobacter pylori treatment‐related side‐effects and also improvement eradication rate. Our aim is to investigate efficacy safety S. related H. eradication. The secondary study was define effect on success anti‐ therapy. Materials methods: One hundred twenty‐four patients with infection (male/female: 44/80, mean age: 48 ± 14.25 year) receiving 14 days triple therapy (clarithromycin...

10.1111/j.1523-5378.2007.00516.x article EN Helicobacter 2007-07-30

To determine the association between Helicobacter pylori (H. pylori) and globus sensation (GS) in patients with cervical inlet patch.Sixty-eight esophageal patches were identified from 6760 consecutive undergoing upper gastrointestinal endoscopy prospectively. In these 68 patches, symptoms of (lump throat), hoarseness, sore throat, frequent clearing cough, dysphagia, odynophagia at least 3 mo duration was questioned prior to endoscopy.Cervical heterotopic gastric mucosa (CHGM) found...

10.3748/wjg.v16.i1.42 article EN PubMed 2010-01-07

Determination of human epidermal growth factor receptor-2 status in advanced gastric cancer is important clinical decision making. In the trastuzumab for GC trial, trastuzumab-based therapy demonstrated a significant overall survival benefit patients with receptor-2-positive cancer. Human discordance primary and its metastases has been long debated. The aim study was to evaluate rate effect on treatment decisions A total 74 were included study. Both immunohistochemical staining dual-color...

10.1093/jjco/hyv020 article EN Japanese Journal of Clinical Oncology 2015-03-02

Hashimoto's thyroiditis is an autoimmune thyroid disorder. Lymphocytic colitis and collagenous are characterized by diarrhea with normal endoscopic findings. Autoimmune disorders common in lymphocytic colitis. The aim of this study was to investigate the incidence patients thyroiditis.Fifty well-documented were included. Twenty nonulcer dyspepsia served as a control group. Five 50 reported intermittent diarrhea, whereas no had All group underwent total colonoscopy, multiple colonoscopic...

10.1097/00004836-200203000-00008 article EN Journal of Clinical Gastroenterology 2002-03-01

Aims and background p53, c-erbB-2 Ki-67 protein expression microvessel density (MVD) determined by CD34 antibody were evaluated immunohistochemistry their correlation with clinicopathological parameters including estrogen (ER) progesterone (PR) receptor status survival investigated in patients axillary lymph node-negative infiltrating ductal breast carcinoma. Methods The study population consisted of 47 Results p53 was detected 36.2% 31.9% patients, respectively. Median 10%. There no...

10.1177/030089160509100109 article EN Tumori Journal 2005-01-01

AIM:To evaluate whether serum and tumor indoleamine 2,3-dioxygenase activities can predict lymphatic invasion (LI) or lymph node metastasis in colorectal carcinoma. METHODS:The study group consisted of 44 carcinoma patients.The patients were re-grouped according to the presence absence LI metastasis.Forty-three cancer-free subjects without any metabolic disturbances included into control group.Serum neopterin was measured by enzyme linked immunosorbent assay.Urinary biopterin, tryptophan...

10.3748/wjg.v22.i13.3592 article EN cc-by-nc World Journal of Gastroenterology 2016-01-01

This prospective study evaluated 382 pediatric patients with peripheral lymphadenopathy (LA) presenting at the Pediatric Oncology and Hematology Departments of Social Security Children's Hospital Gazi University Medical Faculty Hospital. The ages ranged between 2 months 16 years (median 7 years); 72% were male. Of patients, 138 had localized LA (a single anatomic area involved), 171 limited (two or three areas 73 generalized ( four more involved). specific etiology (either benign malign) was...

10.1080/088800199276813 article EN Pediatric Hematology and Oncology 1999-01-01

The aim of this study was to determine number and diameter milk ducts in the nipple investigate possible influences age, breast weight, on ducts. Two hundred twenty-six carcinoma mastectomy specimens were weighed diameters measured. counted histological cross sections. Mean mean weight 13.9 mm 844.6 g, respectively. There a small but statistically significant positive correlation between (rho = 0.158; p 0.01), no with weight. duct bundle 17.5. This is significantly higher than reported open...

10.1159/000096775 article EN European Surgical Research 2006-01-01

Heterotopic gastric mucosa (HGM) is commonly seen in the upper esophagus during endoscopyand generally considered a benign disease. A hyperplastic polyp and an adenocarcinoma arising heterotopic are quite rare occurences.We present two cases: The first patient who suffered from dysphagia because of large that arose HGM; was excised endoscopically. Secondly, we report case HGM cervical esophagus.Morphologic changes or malignant transformation can develop inlet patch. Therefore,...

10.1186/1752-1947-1-127 article EN cc-by Journal of Medical Case Reports 2007-11-02

Near infrared spectroscopy measures tissue oxygenation even when there is complete cessation of blood flow. We evaluated near to diagnose testicular torsion and blindly compared its accuracy with that Doppler ultrasound. also it by immunohistochemical evaluation hypoxia cell viability.Rats were randomized 4 groups, including group 1-720-degree unilateral torsion, 2-360-degree 4-sham operation 4-720-degree followed surgical reduction at minute 180. ultrasound done minutes 0, 5, 30, 60, 180...

10.1016/j.juro.2011.09.145 article EN The Journal of Urology 2011-12-16

Grading and staging are important in gastroenteropancreatic neuroendocrine tumors for directing treatment. In this study, we evaluated the histopathological parameters of statistically analyzed correlations these between World Health Organization (WHO) 2000 2010 classifications.A total 77 cases diagnosed as were included study. Cases classified according to WHO classification systems, differences two systems discussed.Among 50 that well-differentiated tumor 2000, 45 found be Grade 1 5 2...

10.5152/tjg.2014.6579 article EN The Turkish Journal of Gastroenterology 2014-05-21

We investigated the relation of expression tumor-suppressor gene product p53, apoptosis-regulator bcl-2, and CD34 (as a measure microvessel density [MVD]) with traditional clinicopathologic prognostic variables in endometrial carcinoma (histologic type, grade, depth myometrial invasion, angiolymphatic lymph node involvement). In specimens from 63 patients carcinoma, mean MVD (64.38±28.71 microvessels per 200× field) was not related to any variables. Nuclear p53 detected 15 (23.8%) higher...

10.1097/01.pgp.0000070850.25718.a5 article EN International Journal of Gynecological Pathology 2003-07-01

The goals of the present study were to review our archives in order evaluate both diagnostic and prognostic ABSTRACTObjective: We aimed significance DOG1 on gastrointestinal stromal tumors (GISTs), add further insight about those issues current literature including some conflicting results.Material Method: was evaluated 100 cases GISTs, immunohistochemically.Immunostaining index counted for each antibody by using intensity extent staining.The association between immunostaining CD117, CD34,...

10.5146/tjpath.2016.01376 article EN cc-by Turkish Journal of Pathology 2016-01-01

In this study, we measured tissue transglutaminase IgA antibody for the serologic screening of celiac disease in 70 children with epilepsy. A pathologic titer was found eight patients (4.7%). Small intestinal biopsies were performed all antibody-positive patients, and two them had small bowel histology typical (1.17%). Six normal considered to have potential disease. The prevalence epileptic group 1.17%. None serum samples 103 healthy comprising control positive antibody. Therefore, suggest...

10.1177/08830738060210010301 article EN Journal of Child Neurology 2006-01-01

Lamotrigine is an antiepileptic drug that inhibits presynaptic voltage-gated sodium channels and reduces the release of glutamate in pathological states. Neuroprotective effects this have already been demonstrated cerebral ischemia models. The aim present study was to determine inhibition on experimental spinal cord injury (SCI).A total 66 adult Wistar rats were randomly allocated into 6 groups. Group I control group used obtain normal blood samples specimens. Spinal introduced by using...

10.3171/foc.2008.25.11.e6 article EN Neurosurgical FOCUS 2008-11-01
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