A5101652352- Endometrial and Cervical Cancer Treatments
- Ovarian cancer diagnosis and treatment
- Cervical Cancer and HPV Research
- Uterine Myomas and Treatments
- Breast Cancer Treatment Studies
- Medical Imaging Techniques and Applications
- Gastric Cancer Management and Outcomes
- COVID-19 and healthcare impacts
- Breast Lesions and Carcinomas
- Radiopharmaceutical Chemistry and Applications
- Gastrointestinal disorders and treatments
- HER2/EGFR in Cancer Research
- Helicobacter pylori-related gastroenterology studies
- Endometriosis Research and Treatment
- Esophageal and GI Pathology
- Esophageal Cancer Research and Treatment
- Intraperitoneal and Appendiceal Malignancies
- Neuroendocrine Tumor Research Advances
- Eosinophilic Esophagitis
- Lymphoma Diagnosis and Treatment
- Multiple and Secondary Primary Cancers
- Cancer Risks and Factors
- Cancer and Skin Lesions
- Pancreatitis Pathology and Treatment
- Radiomics and Machine Learning in Medical Imaging
National and Kapodistrian University of Athens
2015-2024
Evangelismos Hospital
2019-2024
Laiko General Hospital of Athens
2017-2024
Sociedade Portuguesa de Cardiologia
2024
University of Birmingham
2024
Hospital Vila Franca de Xira
2024
Athens State University
2024
National Institute for Health Research
2024
NIHR Birmingham Biomedical Research Centre
2024
Alexandra Hospital
2014-2023
Mucinous and clear cell histology have been associated with adverse prognosis in ovarian carcinomas. The authors compared the outcome of these subtypes that serous tumors patients who were treated combination paclitaxel/platinum at their center.Four hundred twenty histologically confirmed, (n = 367), mucinous 24), or 29) carcinomas, International Federation Gynecology Obstetrics stage III IV disease, after cytoreductive surgery included this analysis.The median overall survival for each...
Background The aim of the present study was to investigate efficacy adjuvant dose-dense sequential chemotherapy with epirubicin, paclitaxel, and CMF in subgroups patients high-risk operable breast cancer, according tumor subtypes defined by immunohistochemistry (IHC). Materials Methods Formalin-fixed paraffin-embedded (FFPE) tissue samples from 1,039 participating two phase III trials were centrally assessed micro-arrays IHC for 6 biological markers, that is, estrogen receptor (ER),...
Several studies support an important role of angiogenesis in breast cancer growth and metastasis. The main objectives the study were to investigate immunohistochemical expression vascular endothelial factor (VEGF) family ligands (VEGF-A VEGF-C) receptors (VEGFR1, VEGFR2 VEGFR3) their associations with clinicopathological parameters, subtypes/subgroups patient outcome. Formalin-fixed paraffin-embedded tumor tissue samples collected from early-stage patients treated anthracycline-based...
The kidney and upper urinary tract develop through reciprocal interactions between the ureteric bud surrounding mesenchyme. Ureteric branching forms arborized collecting duct system of kidney, while tips promote nephron formation from dedicated progenitor cells. While cells are relatively well characterized, origin progenitors has received little attention so far. It is established that induced nephric duct, an epithelial derived intermediate mesoderm embryo. However, cell state transitions...
Twenty-five years after its first description the p53 protein has been shown to play a key role in both cancer and ageing.The is activated by many different stress pathways, including oncogene action DNA damage.The elucidation of response, which aberrant most cancers (including breast, lung, stomach colorectal cancer), provided new targets for drug development gene therapy now approved China.In tumours where mutant small molecules may be able restore function.In wild-type remains intact but...
To determine appropriate cone dimensions for predicting margin status after large loop excision of transformation zone (LLETZ) treatment.An observational study performed at the Colposcopy Unit a university hospital setting involving patients who underwent LLETZ conisation within 1-year period. Data concerning characteristics, dimensions, lesion grade and margins were recorded.The median age women (n = 61) was 38 years (18-53). specimens had 36.1% cervical intraepithelial neoplasia (CIN)2/3...
Background-Aim To evaluate the prognostic role of elaborate molecular clusters encompassing cyclin D1, E1, p21, p27 and p53 in context various breast cancer subtypes. Methods Cyclin p53, p21 were evaluated with immunohistochemistry 1077 formalin-fixed paraffin-embedded tissues from patients who had been treated within clinical trials. Jaccard distances computed for markers resulted matrix was used conducting unsupervised hierarchical clustering, order to identify distinct groups correlating...
// George Fountzilas 1, 2, * , Eleni Giannoulatou 3, 4 Zoi Alexopoulou 5 Flora Zagouri 6 Timotheadou 7 Kyriaki Papadopoulou 1 Sotiris Lakis Mattheos Bobos Christos Poulios 8 Maria Sotiropoulou 9 Aggeliki Lyberopoulou Helen Gogas 10 Pentheroudakis 11 Dimitrios Pectasides 12 Angelos Koutras 13 Christodoulou 14 Papandreou 15 Epaminontas Samantas 16 Pavlos Papakostas 17 Paris Kosmidis 18 Bafaloukos 19 Charisios Karanikiotis 20 Meletios-Athanassios Dimopoulos Vassiliki Kotoula 8, Laboratory of...
To identify and compare risk factors among endometrial cancer patients ≤40 years of age, postmenopausal women with the same malignancy without malignancy.Retrospective case-control study.Athens University, department obstetrics gynecology a tertiary hospital serving mainly urban population.Endometrial (study group, n = 40), (positive controls, 40) (negative cancer.Clinical history, treatment follow-up were evaluated. Factors studied included histology, stage, grade, lymphovascular space...
The aim of the present study was to identify relationships between uptake radiotracers – namely pentavalent dimercaptosuccinic acid [(V)DMSA] and sestamibi (MIBI) following parameters in primary breast cancer: steroid receptor concentrations (i.e. estrogen [ER] progesterone [PR]), Ki-67 expression, tumor size, grade, age, levels expression p53 c-erbB-2. In addition, by multivariate regression analysis, we further isolated those factors with independent associations (V)DMSA and/or MIBI...
<i>Background/Aims:</i> The differential diagnosis of cystic uterine tumors includes fibroids showing degeneration, adenomyomas, congenital cysts, and developmental anomalies. <i>Methods:</i> incidence, clinical presentation accuracy in preoperative were studied a university hospital population over 6-year period. <i>Results:</i> 29 cases included. Of these, 8 corresponded to the non-fibroid enlargement, 21 that fibroid with degeneration. Age parity...