Ayşa Hacıoğlu

ORCID: 0000-0002-6197-5659
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About
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Research Areas
  • Pituitary Gland Disorders and Treatments
  • Growth Hormone and Insulin-like Growth Factors
  • Adrenal Hormones and Disorders
  • Inflammasome and immune disorders
  • Pancreatitis Pathology and Treatment
  • Pancreatic function and diabetes
  • Adrenal and Paraganglionic Tumors
  • Amyloidosis: Diagnosis, Treatment, Outcomes
  • Fibroblast Growth Factor Research
  • Sexual Differentiation and Disorders
  • Lipoproteins and Cardiovascular Health
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Neuroblastoma Research and Treatments
  • Hormonal Regulation and Hypertension
  • Ovarian function and disorders
  • TGF-β signaling in diseases
  • Gut microbiota and health
  • Kawasaki Disease and Coronary Complications
  • Immunodeficiency and Autoimmune Disorders
  • Lipid metabolism and disorders
  • Tuberculosis Research and Epidemiology
  • Stress Responses and Cortisol
  • Cancer, Lipids, and Metabolism
  • Monoclonal and Polyclonal Antibodies Research
  • Myasthenia Gravis and Thymoma

Erciyes University
2019-2025

Bozok Universitesi
2022

Istanbul University
2013-2021

European Atherosclerosis Society
2021

Istanbul University-Cerrahpaşa
2017-2021

Center for Rheumatology
2015

Abstract Purpose We aimed to investigate the prevalence and diagnostic criteria of hypoprolactinemia in patients with panhypopituitarism effects on depression sexual functions. Materials methods Forty-eight 20 healthy volunteers were included. Basal hormone levels measured a TRH stimulation test was performed. For evaluation functions, questionnaries Female Sexual Functional Index (FSFI) for females International Erectile males performed subjects. Depressive symptoms evaluated by Beck...

10.1007/s11102-024-01393-0 article EN cc-by Pituitary 2024-05-03

Abstract Introduction Pituitary adenomas are the most common lesions of sellar region. The (40%) functional pituitary prolactinomas. Craniopharyngiomas epithelial tumors embryonal origin originating from Rathke's sac. Very few cases collision co-existing with adenoma and craniopharyngioma have been described in literature. Clinical Case We present a case histopathologically proven accompanying prolactinoma 63-year-old female patient diagnosed 40 years ago. She was treated bromocriptine after...

10.1210/jcemcr/luae218.045 article EN cc-by-nc-nd JCEM Case Reports 2025-01-01

Abstract Introduction 17-β-hydroxysteroid dehydrogenase type3 (17β-HSD3) is an enzyme that produces testosterone from androstenedione, encoded by the HSD17B3 gene. Its deficiency causes 46 XY disorder of sex development (DSD) with autosomal recessive inheritance. individuals this can exhibit a wide range phenotypes, ranging normal female external genitalia to ambiguous genitalia. In early childhood, diagnosis might be clinically indistinguishable other DSD such as partial androgen...

10.1210/jcemcr/luae218.008 article EN cc-by-nc-nd JCEM Case Reports 2025-01-01

We aimed to characterize the clinical features and remission rates of patients with Cushing's Disease (CD) without magnetic resonance imaging (MRI) detectable pituitary adenoma compared CD MRI-detectable adenoma.All adrenocorticotropic hormone (ACTH)-dependent syndrome (CS) underwent high-dose dexamethasone suppression test, corticotropin-releasing stimulation and/or bilateral inferior petrosal sinus sampling (BIPSS). The diagnosis in was confirmed when results dynamic testing concordantly...

10.1055/a-2527-2029 article EN Hormone and Metabolic Research 2025-03-01

There are some studies regarding the presence/absence of oxidative stress in patients with hypogonadism limited number parameters. We aimed to investigate effects male and its treatment on Thirteen hypogonadotropic 20 healthy subjects were involved study. Patients evaluated before after six months therapy. Markers indicating lipid protein oxidation, total oxidant status (TOS) anti-oxidant capacity (TAC) evaluated. Control had significantly higher serum testosterone levels comparison...

10.1507/endocrj.ej20-0133 article EN Endocrine Journal 2020-01-01

Results Data of 31 (17F/14M) patients who had received more than 3 injections canakinumab (150mg/mo) were included. The indications insufficient response to colchicine in 22 (>1 attack/month), amyloidosis 6, injection site reaction with anakinra 5, and adverse effects 4 (azoospermia neuropathy one each, myopathy 2). Six concomitant diseases like ankylosing spondylitis polyarteritis nodosa. mean age the was 35,90 ±13 years, disease duration 15±9,30 number 9,80±6 therapy 16±9,26 months. Twenty...

10.1186/1546-0096-13-s1-o45 article EN cc-by Pediatric Rheumatology 2015-09-28

11β hydroxylase deficiency (11βOHD) ranks as the second most common enzyme that causes congenital adrenal hyperplasia. Depending on severity of deficiency, it can lead to cortisol androgen excess and hypertension due increased mineralocorticoid precursor levels. Many different types mutations in CYP11B1 gene located chromosome 8q24.3 have been shown cause 11βOHD. Here, we report a novel missense mutation leads 11βOHD female patient.A 35-year-old patient was admitted Endocrinology Department...

10.2174/1871530322666221007145410 article EN Endocrine Metabolic & Immune Disorders - Drug Targets 2022-10-10

Abstract Objective Primary hypophysitis might be challenging to diagnose, and there is a lack of evidence regarding optimal treatment strategies due rarity the disease. We aim investigate clinical features compare outcomes different management primary in large group patients recruited on nationwide basis. Design A retrospective observational study. Methods The demographic, clinical, radiologic follow-up data were collected study protocol templates analyzed. Results One hundred thirteen...

10.1093/ejendo/lvae101 article EN European Journal of Endocrinology 2024-08-26
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