- Pituitary Gland Disorders and Treatments
- Growth Hormone and Insulin-like Growth Factors
- Adrenal and Paraganglionic Tumors
- Adrenal Hormones and Disorders
- Neuroendocrine Tumor Research Advances
- Thyroid Cancer Diagnosis and Treatment
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Ophthalmology and Eye Disorders
- Cancer Diagnosis and Treatment
- Meningioma and schwannoma management
- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- Ovarian cancer diagnosis and treatment
- Sexual Differentiation and Disorders
- COVID-19 and healthcare impacts
- Cerebrospinal fluid and hydrocephalus
- Diabetes Management and Research
- Parathyroid Disorders and Treatments
- Myasthenia Gravis and Thymoma
- Neuroblastoma Research and Treatments
- Gestational Diabetes Research and Management
- Management of metastatic bone disease
- Peripheral Neuropathies and Disorders
- Thyroid and Parathyroid Surgery
- Bone health and treatments
Sağlık Bilimleri Üniversitesi
2020-2025
Bakırköy Dr.Sadi Konuk Eğitim ve Araştırma Hastanesi
2018-2025
University of Health Science
2021-2025
Turkish Society of Hematology
2024
University of Health Sciences
2021-2023
Istanbul University
2013-2022
Okmeydanı Eğitim ve Araştırma Hastanesi
2013
Dopamine agonist (DA)-induced impulse control disorder (ICD) in patients with prolactinomas is not sufficiently known. To evaluate the prevalence of DA-induced ICDs and possible risk factors related to these disorders prolactinoma. This a cross-sectional multicenter study involving 308 prolactinoma followed up tertiary referral centers who received at least three months DA therapy. (pathological gambling, hypersexuality, compulsive shopping, eating) impulsivity were assessed using...
Abstract Introduction Pregnancy and lactation-associated osteoporosis is a rare type of that often accompanied by vertebral fractures. It considered to be result pregnancy-related factors, as well due underlying secondary causes. Here we present case severe hypocalcemia following parenteral zoledronic acid administration for postpartum osteoporosis, in which further evaluation causes had not been made Celiac disease was missed. Clinical Case A 34-year-old female patient applied an...
Abstract Introduction Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder characterized by impaired steroid hormone synthesis. 21-hydroxylase deficiency (21OHD) the most common form of CAH. There are two main forms 21OHD; salt-wasting and simple virilising. The virilizing diagnosed early in females since it has severe effects on female sexual development; however, males, frequently late-diagnosed because hyperandrogenism could be overlooked. Therefore, male patients with...
Abstract Introduction Although the frequency of adrenal incidentalomas is increasing, they are rarely detected due to lack imaging during pregnancy. Here, we present a case incidentaloma diagnosed Clinical Case A 32-year-old female patient was with mass in liver obstetric ultrasonography performed 4th month pregnancy and referred gastroenterology clinic for further examination, but any additional intervention could not be made because patient’s refusion. She underwent an emergent caesarean...
Abstract Introduction Primary ovarian insufficiency (POI) is characterized by amenorrhea secondary to dysfunction accompanied high gonadotropin levels in women before the age of 40. Autoimmunity estimated account for 5-17% POI etiologies. Although it varies according its subtype, prevalence patients with autoimmune polyglandular syndrome (APS) reported be between 16% and 40%. It may take several years recognize syndrome. Generally, a multidisciplinary approach needed diagnose treat cases...
Abstract Introduction Pituitary apoplexy is a rare endocrinological emergency that may be life-threatening due to pituitary hormone deficiency or compression effect, if not treated appropriately. It usually develops secondary acute ischemia hemorrhage in the gland and presents with headache, vomiting, ophthalmoplegia, vision loss. In this case, we aim present case of who applied service complaint developed ophthalmoplegia while hospitalized. Clinical Case A 76-year-old male patient...
Abstract Introduction Maturity-onset diabetes (MODY) is a rare type of mellitus (DM) with autosomal dominant inheritance that occurs at young age, constituting 1-2% all DM cases. Most MODY cases are misdiagnosed as 1 or 2 DM. MODY9 caused by mutation in the Paired box gene 4 (PAX4). We aimed to present case had been followed for eight years, initially diagnosed DM, but later 9 after PAX4 was detected result genetic analysis. Clinical Case A 23-year-old male patient up years diagnosis In...
Abstract Introduction Most gonadotropinomas are nonfunctional macroadenomas, usually diagnosed by immunohistochemical staining. Here, a rare case of functional gonadotropinoma will be presented. Clinical Case A 37-year-old female patient applied to the neurology clinic with severe headache, and macroadenoma was detected on cranial magnetic resonance imaging(MRI). She referred our endocrinology clinic. Her menstrual cycle irregular, she had frequent intermenstrual bleeding for about year. has...
Detection of early vascular changes prior to clinical manifestations atherosclerosis, such as increased arterial carotid intima-media thickness (CIMT) and impaired endothelial function is paramount importance for identification subjects at risk accelerated atherosclerosis. The present study was designed evaluate the relationship between atherosclerosis dysfunction in type 1 diabetic patients based on measurements CIMT soluble CD146 (sCD146) levels.Thirty-seven with diabetes, 14 males (37.8%)...
Objective The aim of this study was to determine the frequency central thyroid dysfunctions in Cushing's syndrome (CS). We also aimed evaluate hyperthyroidism due inappropriate secretion TSH (SITSH), which recently defined patients with insufficient hydrocortisone replacement after surgery. Materials and methods evaluated functions (TSH free thyroxine [fT4]) at time diagnosis, during hypothalamo-pituitary-adrenal axis recovery, surgery 35 CS. were separated into two groups: ACTH-dependent CS...
In this study, we aimed to evaluate the presence of glucose metabolism abnormalities and their impact on IGF-1 levels in patients with acromegaly. Ninety-three acromegaly (n=93; 52 males/41 females) were included study. Patients separated into three groups such as; normal tolerance (n=23, 25%), prediabetes (n=38, 41%), diabetes mellitus (n=32, 34%). Insulin resistance was calculated homeostasis model assessment (HOMA). HOMA-IR > 2.5 or ≤2.5 defined as insulin resistant noninsulin groups,...
The granulation pattern of pituitary tumors may be important to predict tumor behavior, treatment outcomes, and recurrences. Therefore, we compared densely granulated corticotroph (DGCT) sparsely (SGCT) in terms clinicopathologic findings.A total 41 patients (31 females/10 males) were assessed the study. patterns detected by Periodic Acid-Schiff (PAS) adrenocorticotropic hormone (ACTH) immunoreactivity. Diffuse strong staining PAS ACTH identified as DGCT, whereas faint focal, weak SGCT....
The purpose of this study was to determine possible cut-off levels basal DHEA-S percentile rank in the differential diagnosis patients with Cushing's syndrome (CS) ACTH gray zone and normal levels. In retrospective including 623 pathologically confirmed CS, calculated 389 within reference interval. were classified as group 1 (n=265 disease; CD), 2 (n=104 adrenal CS) 3 (n=20 ectopic syndrome).ROC-curve analyses used calculate optimal level interval effectiveness identification accurate...
Aims: Aryl hydrocarbon receptor-interacting protein (AIP) gene mutations have long been associated with apparently sporadic pituitary adenomas (PAs) a prevalence range of 0-12%. The aim this study was to evaluate the frequency germline AIP variations in large cohort PAs diagnosed before age 40 years, who did not exhibit hypercalcemia and/or MEN1 syndrome components during long-term follow-up. Materials and Methods: A total 97 patients, functional ≤40 years old, composed somatotropinoma (n =...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Sahbaz N, Dural A, Akarsu C, et al. Transperitoneal laparoscopic surgery in large adrenal masses. Videosurgery and Other Miniinvasive Techniques. 2020;15(1):106-111. doi:10.5114/wiitm.2019.85177. APA Sahbaz, N., Dural, A., Akarsu, C., Guzey, D., Kulus, M., & Dogansen, S. (2020). Techniques, 15(1), 106-111. https://doi.org/10.5114/wiitm.2019.85177 Chicago Nuri Alper, Ahmet Cem Cevher Deniz Mehmet Sema Ciftci...