- Pituitary Gland Disorders and Treatments
- Thyroid Disorders and Treatments
- Growth Hormone and Insulin-like Growth Factors
- Thyroid Cancer Diagnosis and Treatment
- Adrenal and Paraganglionic Tumors
- Neuroendocrine Tumor Research Advances
- Glioma Diagnosis and Treatment
- Vitamin D Research Studies
- Hormonal Regulation and Hypertension
- Cancer, Hypoxia, and Metabolism
- Parathyroid Disorders and Treatments
- Meningioma and schwannoma management
- Neuroblastoma Research and Treatments
- Myasthenia Gravis and Thymoma
- Thyroid and Parathyroid Surgery
- Gestational Diabetes Research and Management
- Bone health and osteoporosis research
- Pancreatic and Hepatic Oncology Research
- Head and Neck Anomalies
- Diabetes Management and Research
- Pulmonary Hypertension Research and Treatments
- Adrenal Hormones and Disorders
- Liver Disease Diagnosis and Treatment
- Diabetes Treatment and Management
- Diabetes, Cardiovascular Risks, and Lipoproteins
Namık Kemal University
2015-2024
Şişli Etfal Eğitim ve Araştırma Hastanesi
2011-2016
Endocrinology Research Center
2011
Istanbul University
2011
Istanbul University-Cerrahpaşa
2010
OBJECTIVE:To assess the relationship between low maternal serum 25-hydroxyvitamin D levels and gestational diabetes mellitus in Turkish pregnant women according to severity of deficiency intact parathyroid hormone with controls sufficient levels.METHODS: We analyzed 234 168 controls.To define status, were further classified into severely deficient, insufficient groups.RESULTS: Women had significantly lower compared (30.8¡16.3 vs. 36.0¡16.2nmol/L).However, when subgroups analyzed, was more...
Abstract Background: Helicobacter pylori infection is a most frequent cause of chronic gastritis. H. may decrease absorption oral thyroxine by decreasing gastric acid secretion in the stomach. In this study, we aimed to investigate change thyroid function tests cases after eradication who were not responding high doses treatment before eradication. Methods: Hypothyroid among ones presented Endocrinology and Gastroenterohepatology Clinics Sisli Etfal Training Research Hospital between 2009...
To compare anterior pituitary functions between subjects with total and partial primary empty sella (PES) to assess whether all cases PES need endocrinological evaluation.Eighty-one (34 47 partial) were included in the study. Basal its target hormones assessed those low insulin like growth factor-1 and/or basal cortisol levels underwent tolerance test (ITT).67.4% of 14.9% had different degrees hypopituitarism. However, frequency hypopituitarism was significantly higher PES. The odds ratio...
Acute pancreatitis (AP) is a common systemic inflammatory disorder of the pancreas. The data related to lipid changes in patients with AP were insufficient. In this study, we aimed investigate relation between high-density lipoprotein (HDL) and other parameters severity disease cases.Seventy-five cases admitted Gastroenterohepatology Clinic diagnosis included study. Ranson scores Glasgow used for prognosis. Lipid evaluated first 24 hours after clinic laboratory remission.The causes among...
Abstract Recently, the Gravesʼ Recurrent Events After Therapy score (GREAT) was proposed as a useful tool to predict relapse before starting antithyroid drugs (ATD) in patients with disease (GD). Therefore, we intended assess validity of GREAT Turkish GD, including who experienced poorly controlled (multiple episodes hyperthyroidism followed by euthyroidism or rarely hypothyroidism) during ATD dose titration. This is retrospective multicenter study 517 first episode GD were treated for at...
Screening of the community for diabetes is generally costly and imposes a significant financial burden. Therefore, some non-invasive measures such as Finnish Diabetes Risk Score (FINDRISK) Scale have been developed are recommended screening people, particularly those with high risk diabetes. However, university employees including academics FINDRISK scale has not performed so far. in this study, we intended to assess by FINDRISC among other well make awareness them.
Although the TSH-receptor antibody (TRAb) plays a central role in pathogenesis of Graves' disease (GD), association between TRAb at first diagnosis and clinical laboratory parameters is not well known. On other hand, minority patients with GD may be negative, there lack adequate evidence to demonstrate characteristics these patients. Therefore, we aimed investigate initial large number compare high levels TRAb-negative patients.This study included 440 [326 (74%) female, 114 (26%) male]. All...
OBJECTIVE:To determine the role of peak systolic velocity, end-diastolic velocity and resistance indices both right left inferior thyroid arteries measured by color-flow Doppler ultrasonography for a differential diagnosis between gestational transient thyrotoxicosis Graves' disease during pregnancy. METHODS:The artery-peak 96 patients with (41 thyrotoxicosis, 31 age-matched pregnant 24 age-and sex-matched non-pregnant disease) 25 ageand healthy euthyroid subjects were assessed...
To determine the immunohistochemical expression of ErbB2 in adamantinomatous craniopharyngiomas (ACP) and to assess its relationship with nuclear β-catenin surgically resected human ACP tissue sections estimate whether these tumors could be candidates for anti-ErbB2 therapy.The immunostaining was performed on paraffin embedded 20 using avidin-biotin-peroxidase complex method. immunoreactivity interpreted according American Society Clinical Oncology/ College Pathologists criterions breast...
Introduction: Normocalcaemic hyperparathyroidism is a condition first defined in 2008, characterized by normal serum calcium and high parathormone levels. Although normocalcaemic considered to have milder clinical picture compared asymptomatic primary hyperparathyroidism, recent studies shown that it may be associated with osteoporosis, insulin resistance, metabolic syndrome, cardiovascular risk factors. Considering pose the setting of carotid atherosclerosis, we sought examine structural...
Late-night salivary cortisol is a frequently used and easily implemented diagnostically valuable test for the diagnosis of overt Cushing's syndrome. The use late-night in subclinical syndrome somewhat controversial. In this study, we aimed to determine diagnostic value diagnosing compare it with 24-hour urinary free levels (UFC).The study consisted 33 cases syndrome, 59 non-functioning adrenal adenoma, 41 control subjects. UFC were measured all cases. was based on combined results 1 mg...
Introduction: The outcome of medical treatment in patients with Graves' disease (GD) is generally difficult to predict. In this study, we examined the hypothesis that gender may affect antithyroid drugs (ATDs). Material and methods: This a retrospective multicentre study including 717 (514 female 203 male) first episode GD treated for at least 12 months. Patients were classified as relapse, poorly controlled (several episodes hyperthyroidism followed by euthyroidism rarely hypothyroidism,...
Abstract Objectives Skin changes in acromegaly are often the first sign of disease. The aim this study was to describe cutaneous findings patients with acromegaly. In addition, a secondary investigate possible association these remission status and concomitant endocrinopathies. Design, Patients, Measurements prospective multicenter study, 278 over age 18 years who were followed up 14 different tertiary healthcare institutions included. These patients, by Endocrinology Department, then...
To assess the relation between fetal and maternal blood type (ABO, Rh) incompatibility development of gestational diabetes mellitus (GDM).A total 500 pregnant women underwent diagnostic test for GDM by a 100-g oral glucose tolerance (OGTT) after an 8 to 12-h overnight fast participated in this study. OGTT was performed 24-28 weeks gestation, but participants who were at high risk tested first prenatal visit. In postpartum period, infant types determined. Presence evaluated terms matched...