A5050329466- Gastric Cancer Management and Outcomes
- Colorectal Cancer Treatments and Studies
- Lung Cancer Treatments and Mutations
- Gastrointestinal Tumor Research and Treatment
- Alkaline Phosphatase Research Studies
- Cardiovascular Disease and Adiposity
- Atrial Fibrillation Management and Outcomes
- Bone and Joint Diseases
- Bone health and osteoporosis research
- Esophageal Cancer Research and Treatment
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Genetic factors in colorectal cancer
- Cancer, Lipids, and Metabolism
- Chemical Reactions and Mechanisms
- Advanced Breast Cancer Therapies
- Selenium in Biological Systems
- Cancer-related cognitive impairment studies
- Iron Metabolism and Disorders
- Lipid metabolism and disorders
- Film in Education and Therapy
- Genomics, phytochemicals, and oxidative stress
- Retinal Diseases and Treatments
- Banking stability, regulation, efficiency
- BRCA gene mutations in cancer
- Prostate Cancer Diagnosis and Treatment
Trakya University
2023
Eskişehir Osmangazi University
2021-2022
Sağlık Bilimleri Üniversitesi
2018-2021
Sivas State Hospital
2018-2021
Ankara Onkoloji Eğitim ve Araştırma Hastanesi
2021
Framingham State University
2021
Eskişehir Osmangazi Üniversitesi Tıp Fakültesi Hastanesi
2021
Şişli Etfal Eğitim ve Araştırma Hastanesi
2014-2018
Muğla University
2017
Atatürk University
2001-2003
Docetaxel and cisplatin in combination with fluorouracil (DCF) regimen is accepted to be one of the standard regimens treatment advanced gastric cancer. However, substantial toxicity has limited its use daily clinical practice. Therefore, modification DCF regimens, including introduction capecitabine been investigated improve safety profiles. In present study, efficacy a modified dose docetaxel oral (DCX) was evaluated untreated patients HER2-negative cancer.Fifty-four locally or metastatic...
This study investigated the correlation between homocysteine levels in patients with Acute Coronary Syndrome and GRACE Score.This included 191 cases -140 Non-ST MI 51 ST-elevation Şişli Etfal Training Research Hospital Intensive Care Unit December 2008 March 2010. Homocysteine was measured by immulite 2000 device, using kemiluminesans method competitive immunoassay principle a kit DPC used during measurement. The reference range given producing company 5-15 Mmol/L for male female adults....
The aim of this study is to evaluate the correlation between epicardial adipose tissue thickness and oxidative stress parameters in patients with polycystic ovarian syndrome.The included 35 PCOS healthy women. Transthoracic echocardiography was used measure (EATT) all patients. For patients, serum TOS, TAS, hs-CRP, insulin levels were measured according literature, HOMA-IR values calculated. Independent samples t-test, Pearson's analysis, multivariate logistic regression receiver operator...
In this research, carbonic anhydrase enzyme, which was taken from the bones of an animal, purified and characterized for first time. For this, a young cow were used. The purification treatment completed in three steps. Three different isoenzymes, such as peripheral, cystolic, integral bone-cell cytozolic isoenzyme characterized. technique affinity chromatography, utilized Sepharose-4B-L-Tyrosine-Sulphanylamide, measuring activities enzymes, two methods applied. These are esterase that...
Optical coherence tomography angiography (OCT-A) may enable the identification of alteration in retinochoroidal microvasculature patients with iron deficiency anaemia.To investigate presence macular microvascular alterations females IDA by using OCT-A.This is a cross-sectional comparative study. Forty and 35 age-matched healthy women underwent complete ophthalmologic examination OCT-A imaging. Foveal avascular zone parameters vessel density superficial (SCP) deep capillary plexus (DCP) were...
Late-night salivary cortisol is a frequently used and easily implemented diagnostically valuable test for the diagnosis of overt Cushing's syndrome. The use late-night in subclinical syndrome somewhat controversial. In this study, we aimed to determine diagnostic value diagnosing compare it with 24-hour urinary free levels (UFC).The study consisted 33 cases syndrome, 59 non-functioning adrenal adenoma, 41 control subjects. UFC were measured all cases. was based on combined results 1 mg...
Warfarin is the most frequently used therapy as an oral anticoagulant medication for reducing risk of thromboembolic complications. However, poor adherence to may cause ineffective INR levels with increased complication risk. In our study, we aimed show rates awareness patients atrial fibrillation (AF) using warfarin and whether they achieved targeted values.In this 300 male (60%, n=180) female (40%, n=120) over 18 years age who applied polyclinic were receiving treatment due AF included....
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The aim of our study was to assess the impact combination HALP score with TTCR on OS and PFS in PC patients who developed castration resistance.
Abstract Two distinct genetic mutational pathways characterized by either chromosomal instability or high‐frequency microsatellite (MSI‐H) are recognized in the pathogenesis of colorectal cancer (CRC). Recently, it has been shown that patients with primary CRC displays MSI‐H have a significant, stage‐independent, multivariate survival advantage. Biological properties CMS1 (MSI‐H type) can affect therapeutic efficiencies agents used treatment CRC, and therefore become new predictive factor...
Abstract In this research, acid phosphatase was purified and characterized from approximately 3000-year-old human bones archeological excavations. Using anion exchange chromatography, two isoenzymes, TrACP TsACP, were isolated the bone. TsACP eluted separately, with a concentration gradient, CM-sepharose column. The resulting further on cellulose phosphate activity determined by using pNPP as substrate. Additionally, protein Bradford Coomassie Brilliant Blue method. optimum pHs of 6 5,...
Hipertansiyon, çoğu yaşlı insanın mustarip olduğu bir hastalıktır. Yüksek tansiyonu olan insanlar genellikle hayatları boyunca sağlıklı yaşam sürdürebilmek için kan basıncını düşüren ilaçları kullanmak zorundadırlar. Bu çalışmada, lisiniprol adlı hipertansiyon ilacının kemik yapım ve yıkımının göstergesi alkalen fosfataz (ALP) tartarata dayanıklı asit (TrACP) enzimlerinin aktiviteleri üzerine etkilerini in vitro olarak incelenmiştir. İnsan serumundan enzimi DEAE-selüloz, ise CM-selüloz iyon...
Diabetes mellitus (DM) is a chronic metabolic disease requiring lifelong medical care, and its prevalence increasing worldwide. Early diagnosis of prediabetes diabetes significant in view the mortality, morbidity cost associated with them. Because difficulties application reproducibility oral glucose tolerance test (OGTT), which considered to be gold standard DM, more feasible diagnostic tests are needed. This study aims evaluate validity hemoglobin A1c (HbA1c) predicting Turkish population...
The present study aims to compare different types of insulin concerning treatment success and dose requirement in type 2 diabetes patients who were receiving basal-bolus therapy evaluate the causes failure despite high doses insulin.In our retrospective study, 198 included. Patients divided into three groups according (Group 1: short long-acting analogue users (n=83), Group 2: human regular (n=58), 3: + (57)). Demographic data daily recorded from patient follow-up files. These rates...
Myrosinaz glukosinolatlarin hidrolizinden sorumlu bir enzimdir (E.C: 3.2.3.2 I²-thioglucosidase, I²-thioglucoside glucohydrolase olarak da bilinir). Kanserle mucadele icin umut verici bilesikler kabul edilen sinigrin, glukoraphanin (GRA) ve glukoraphenin (GRE) gibi ara yikim urunlerinden dolayi bazi alifatik glukosinolatlar oldukca ilgi cekmis ve myrosinaz enziminin bu tumor kucultucu etkisi son yillarda onem kazanmistir. Bu calismada, amonyum sulfat cokturmesi, Q-sepharose, Konkanavalin...
e15055 Background: Docetaxel and cisplatin in combination with fluorouracil (DCF) is accepted to be one of the standard regimens advanced gastric cancer, but substantial toxicity has limited use this regimen daily clinical practice. Therefore, modification DCF regimen, including introduction capecitabine have been investigated improve safety profiles. In present study, efficacy a modified dose docetaxel oral (DCX) were evaluated untreated patients HER-2 negative cancer. Methods:...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)