Erol Çakmak

ORCID: 0000-0002-6468-3483
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About
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Research Areas
  • Esophageal and GI Pathology
  • Liver Disease Diagnosis and Treatment
  • Hepatitis B Virus Studies
  • Hepatitis C virus research
  • Lipid metabolism and biosynthesis
  • Drug-Induced Hepatotoxicity and Protection
  • Pediatric Hepatobiliary Diseases and Treatments
  • Celiac Disease Research and Management
  • Tracheal and airway disorders
  • Ubiquitin and proteasome pathways
  • Gallbladder and Bile Duct Disorders
  • Biliary and Gastrointestinal Fistulas
  • Lymphoma Diagnosis and Treatment
  • Foreign Body Medical Cases
  • Potassium and Related Disorders
  • Organ and Tissue Transplantation Research
  • Inflammatory Biomarkers in Disease Prognosis
  • Bone health and osteoporosis research
  • Hepatitis Viruses Studies and Epidemiology
  • Research in Cotton Cultivation
  • Ovarian function and disorders
  • Adipose Tissue and Metabolism
  • Endoplasmic Reticulum Stress and Disease
  • Drug Transport and Resistance Mechanisms
  • Intestinal and Peritoneal Adhesions

Sivas Cumhuriyet Üniversitesi
2010-2021

Sağlık Bilimleri Üniversitesi
2021

Ümraniye Eğitim ve Araştırma Hastanesi
2021

Ordu University
2015

Hitit Üniversitesi Çorum Eğitim ve Araştırma Hastanesi
2015

Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi
2015

Sivas State Hospital
2015

Memorial Sisli Hospital
2014

Erciyes University
2006

Dicle University
2003

Obstructive sleep apnea (OSA) is a major disease that can cause significant mortality and morbidity. Chronic intermittent hypoxia potential causal factor in the progression from fatty liver to nonalcoholic steatohepatitis.This study evaluated association between degree of steatosis severity nocturnal hypoxia.In this study, December 2011 2013, patients with ultrasound-diagnosed NAFLD by standart polysomnography were subsequentally recorded. Patients alcohol use, viral hepatitis other chronic...

10.5812/hepatmon.32655 article EN cc-by Hepatitis Monthly 2015-11-03

Abstract Objective Sclerostin is an osteocyte-secreted endogenous inhibitor of Wnt signaling. Several systemic and local factors have been suggested as possible regulators sclerostin expression by osteocytes. In this study, we examined the effect vitamin D treatment on levels. Subject Methods 44 patients with diagnosis deficiency (25(OH)D≤20 ng/ml) were involved in study. Patients had monthly intramuscular injection 300.000 IU cholecalciferol for 3 consecutive months. Sclerostin, 25(OH)D,...

10.1055/s-0035-1559790 article EN Experimental and Clinical Endocrinology & Diabetes 2016-01-29

BACKGROUND This study aimed to investigate ovarian reserve in patients of reproductive age with Celiac disease (CD) using anti-Müllerian hormone (AMH) levels, antral follicle counts (AFCs), and volume. MATERIAL AND METHODS We included into this 46 CD female 40 healthy subjects age, ages 18-45 years. Venous blood samples were taken from both groups on days 2-4 the menstrual cycle, stimulating (FSH), luteinizing (LH), estradiol (E2), prolactin (PRL), AMH levels measured. On same day, AFCs...

10.12659/msm.909033 article EN Medical Science Monitor 2018-02-24

Although alveolar echinococcosis (AE) can cause a serious disease with high mortality and morbidity similar to malign neoplasms. A 62-year-old woman admitted hospital located in Sivas, Turkey, the complaints of fatigue right upper abdominal pain. On contrast CT, 54×70×45 mm sized cystic lesion was detected left lobe liver that seen extend posterior mediastinum invade diaphragm, esophagus, pericardium. The be occluding inferior vena cava hepatic vein at level where veins poured into cava....

10.3347/kjp.2013.51.4.475 article EN Korean Journal of Parasitology 2013-08-30

Evaluation of liver fibrosis is important for treatment decisions, complications and to predict prognosis in patients with chronic hepatitis B (CHB). Our aim was develop a new non-invasive scoring method prove its accuracy the differentiation no/low grade advanced CHB.Our study included 273 who underwent biopsy from February, 2007 2019 medical records retrospectively reviewed. Preparations these were divided into two groups as ≤ 3 no-low (n=236) ≥ 4 (n=37) according histological ISHAK...

10.1016/j.aohep.2021.100544 article EN cc-by-nc-nd Annals of Hepatology 2021-09-24

An acceleration of the wound healing process expedites chronic patient's return to normal social environments significantly. Sildenafil, a cyclic guanosine monophosphate (cGMP)-dependent phosphodiesterase- 5 inhibitor has been shown be potent stimulator angiogenesis through upregulation cGMP. In our study, sildenafil was administered orally as cost-effective supplement in treatment full thickness defects and wounds that manner with low incidence side effects morbidity.Randomly selected 72...

10.4149/bll_2014_055 article EN Bratislavské lekárske listy/Bratislava medical journal 2014-01-01

Fas (CD95/APO-1) is a protein that mainly related to apoptosis of lymphoid cells. The increment expression associated with long-term survival in various malignancies. However, there are limited studies regarding the effect on course and prognosis non-Hodgkin's lymphoma. aim this study was investigate significance immunohistochemical nodal diffuse large B-cell A total 63 patients primary lymphoma diagnosed Erciyes University Department Hematology between 1990 2003 were included study. median...

10.1002/ajh.20564 article EN American Journal of Hematology 2006-04-20

Paraneoplastic syndromes are functional clinical disorders caused by the direct effect of primary tumor or metastasis.The initial presenting symptom patients may be associated with paraneoplastic manifestations.Paraneoplastic cholestasis is most frequently defined in association renal cell carcinoma (Stauffer's syndrome), but it an extremely rare entity seen prostate cancer.Etiology was investigated case diagnosed as metastatic cancer who applied to gastroenterology outpatient clinic due...

10.5152/tud.2018.52059 article EN Turkish journal of urology 2018-09-13

A 28-year-old female patient was admitted to our hospital with right upper quadrant pain and fever. The diagnosed acute cholangitis choledocholithiasis. Stone removal performed Endoscopic retrograde cholangiopancreatography (ERCP) as it measured 1cm in size a 10-Fr 10 cm straight plastic stent (Flexima™, Boston Scientific) placed the common bile duct. discharged after his symptoms subsided again two months later abdominal pain, back nausea vomiting. On physical examination, mild tenderness...

10.17235/reed.2022.8514/2021 article EN publisher-specific-oa Revista Española de Enfermedades Digestivas 2022-01-01

Background There are limited data about the mortality and morbidity of patients with HBV flare related to immunosuppressive treatments (IST) in third-generation antivirals era. Herein, we performed a multi-centric study treated entecavir (ETV) or tenofovir disoproxil fumarate (TDF) evaluated their clinical course. Methods The group included who were referred gastroenterology infectious disease specialists at eight different hospitals Turkey. was defined as least threefold elevation alanine...

10.3851/imp3356 article EN Antiviral Therapy 2019-04-01

Objective: The aim of this study was to investigate the real-world efficacy and safety in Turkey paritaprevir/ritonavir, ombitasvir, dasabuvir (PrOD) ± ribavirin (RBV) ledipasvir/sofosbuvir (LDV/SOF) RBV combination regimens used for chronic hepatits C virus (HCV) genotype 1 patients, which is most common form disease seen both worldwide. Method: included a total 81 HCV patients receiving PrOD or LDV/SOF treatment between June 2016 October 2017. were evaluated respect demographic, clinical...

10.7197/223.vi.376221 article EN Cumhuriyet Tıp Dergisi/Cumhuriyet Üniversitesi Tıp Fakültesi dergisi 2018-03-19

To determine the presence of microplastics in stomach, and relationship between pathological changes stomach tissue microplastics.

10.29271/jcpsp.2024.09.1035 article EN Journal of College of Physicians And Surgeons Pakistan 2024-09-01

Objective: The majority of the liver function tests are not specific to liver. histological damage begins before patients diagnosed with cirrhosis and continues afterwards. Therefore, there is an increasing demand for early markers that correlated damage. This study aims investigate if serum urinary fatty acid-binding protein (L-FABP) levels could be used as diagnostic marker cirrhosis.
 Material Methods: cross-sectional included 30 compensated cirrhosis, 27 decompensated healthy...

10.36472/msd.v8i4.516 article EN Medical Science and Discovery 2021-04-15

A 61-year-old woman was admitted to the hospital because of persistent vomiting and diarrhea for past year. In esophagogastroduodenoscopy performed etiology these symptoms, a fistula seen in descending part duodenum without any erosion ulceration. The mouth about 8 mm wide, endoscopy used view transverse colon from ([Fig. 1]). Colonoscopy revealed hepatic flexure diverticulum nearby 2]). No additional pathology such as tumors or ulcers colon. During esophagogastroduodenoscopy, on closed by...

10.1055/a-1559-1830 article EN Endoscopy 2021-09-08

Objective: P53, Bcl-2, and Fas proteins play significant roles in lymphoid cell apoptosis.These affect the prognosis treatment response of lymphoma various malignancies.The aim present study was to investigate effects protein expression on patients with primary gastrointestinal diffuse large B-cell lymphoma.Materials Methods: Thirty-nine were included study.Immunohistochemical staining performed analyze levels paraffin sections.Results: We examined 39 lymphoma, 21 males 18 females, a median...

10.5152/etd.2015.150001 article EN Deleted Journal 2015-10-20

Trakea-özofageal fistül, konjenital veya akkiz olan özofagus ve trakea arasında bağlantı olmasıdır. Akkiz trakea-özofageal fistül malign nonmalign olmak üzere ikiye ayrılır. en sık nedeni malignitedir. Non fistülün ise uzamış mekanik ventilasyona bağlı endotrakeal kaf ile ilişkili travmadır. Endotrakeal basıncı, ortalama doku kapiller perfüzyon basıncı geçtiğinde lokal mukozasında iskemi nekroza neden olur. Hastamız 33 yaşında erkek, organik fosfor zehirlenmesi sonrası uzun süreli entübasyon...

10.17940/endoskopi.74807 article TR Endoskopi Gastrointestinal 2015-04-03

Abstract Although it is rare, drug -induced thrombocytopenia important since may cause fatal results like bleeding. Mostly spironolactone used for ascites palliation in the cirrhotic patients. Thrombocytopenia has been reported with thiazide group of diuretics. But caused by rarely seen. We presented our patient diagnosed as liver cirrhosis that developed severe after receiving two weeks treatment. Keyword: Liver cirrhosis, spironolactone, Ozet Ilaca bagli trombositopenide nadir olmasina...

10.7197/cmj.v35i2.1008001265 article EN Cumhuriyet Tıp Dergisi/Cumhuriyet Üniversitesi Tıp Fakültesi dergisi 2013-06-27
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