Erdem Akbal

ORCID: 0000-0003-0651-2472
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About
Contact & Profiles
Research Areas
  • Gastrointestinal disorders and treatments
  • Liver Disease Diagnosis and Treatment
  • Pancreatitis Pathology and Treatment
  • Helicobacter pylori-related gastroenterology studies
  • Esophageal and GI Pathology
  • Gastrointestinal motility and disorders
  • Pituitary Gland Disorders and Treatments
  • Eosinophilic Esophagitis
  • Tracheal and airway disorders
  • Inflammatory Bowel Disease
  • Growth Hormone and Insulin-like Growth Factors
  • Gallbladder and Bile Duct Disorders
  • Adipokines, Inflammation, and Metabolic Diseases
  • Intestinal and Peritoneal Adhesions
  • Cardiovascular Disease and Adiposity
  • Liver Disease and Transplantation
  • Gastric Cancer Management and Outcomes
  • Hemostasis and retained surgical items
  • Appendicitis Diagnosis and Management
  • Diet, Metabolism, and Disease
  • Peroxisome Proliferator-Activated Receptors
  • Hepatitis C virus research
  • Thyroid Disorders and Treatments
  • Hepatitis B Virus Studies
  • Surgical Sutures and Adhesives

Istanbul Bilim University
2017-2022

Memorial Sisli Hospital
2021

Çanakkale Onsekiz Mart Üniversitesi
2013-2019

Siirt Üniversitesi
2013

Ministry of Health
2007-2013

GTx (United States)
2013

Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi
2009-2012

Turkish Thoracic Society
2012

Education Training And Research
2009-2012

Ulucanlar Göz Eğitim ve Araştırma Hastanesi
2011

The aim of this study was to evaluate the potential use serum transforming growth factor-β1 (TGF-β1), tissue inhibitor metalloproteinase-1 (TIMP-1), fetuin-A, and fibroblast factor 21 (FGF21) in detection liver fibrosis patients with chronic hepatitis B (CHB). value noninvasive models - that is, aspartate aminotransferase platelet ratio index (APRI), based on four factors (FIB-4) score, Forn's also examined.CHB who underwent biopsy for evaluation were included study. A total 73 divided into...

10.1097/meg.0b013e32835fd699 article EN European Journal of Gastroenterology & Hepatology 2013-03-22

Background In recent years, white blood cells (WBCs) and their subtypes have been studied in relation to inflammation. The aim of our study was assess the relationship between neutrophil–lymphocyte ratio (NLR) ankylosing spondylitis (AS). Materials methods We enrolled a total 177 patients, 96 AS 81 healthy controls. Complete count, WBC, neutrophil lymphocyte levels were measured, NLR calculated. assessment AS, we used erythrocyte sedimentation rate, C‐reactive protein (CRP), Bath Ankylosing...

10.1002/jcla.21768 article EN Journal of Clinical Laboratory Analysis 2014-05-21

Helicobacter pylori infection is reported to be associated with some extragastrointestinal manifestations, such as hematological diseases (thrombocytopenia, anemia), obesity, and fatty liver disease. The length or the volume ratio of spleen was suggested changed in hepatobiliary disorders. We hypothesized that liver-to-spleen may affected H. pylori-positive patients. In this respect, we aimed evaluate effect on platelet indices.A total 174 patients functional dyspepsia were included study....

10.1097/meg.0b013e3283590c10 article EN European Journal of Gastroenterology & Hepatology 2012-09-26

The ingestion of caustic substances may result in significant esophageal injury. There is no standard treatment protochol for injury and most patients are treated with a proton pump inhibitor or H2 antagonist. However, there clinical study evaluating the efficacy omeprazole A prospective 13 adult (>18 years age) who were admitted to our hospital between May 2010 June was conducted. Mucosal damage graded using modified endoscopic classification described by Zargar et al. Patients maintained...

10.1111/j.1442-2050.2011.01319.x article EN Diseases of the Esophagus 2012-02-14

Vascular thrombosis and systemic hypercoagulable states are known complications of pancreatitis. Higher levels mean platelet volume (MPV) have been associated with thrombotic diseases. However, a few studies investigated the association between acute pancreatitis MPV. We aimed to investigate whether there is difference MPV coagulation parameters in patients active remission included 24 consecutive biliary healthy age-matched sex-matched controls. Full blood counts other laboratory tests were...

10.1097/mbc.0b013e32835aef51 article EN Blood Coagulation & Fibrinolysis 2013-02-22

Background and aims. Non-alcoholic fatty liver disease (NAFLD) is one of the most common pathology worldwide strongly associated with obesity insulin-resistance food intake. Nesfatin-1 a new peptide that controls appetite The objective this research was to examine serum concentrations nesfatin-1 in NAFLD. Material methods. Thirty NAFLD patients who had elevated enzymes 40 age- sex-matched healthy subjects were included study. diagnosed graded findings ultrasound scan. measured using an ELISA...

10.3109/00365513.2012.699097 article EN Scandinavian Journal of Clinical and Laboratory Investigation 2012-09-05

Background: The exact etiology of irritable bowel syndrome (IBS) remains unclear. Curative treatment is not available and current modalities are mainly directed against the predominant symptoms. There a few studies reporting beneficial effects transcutaneous electrical stimulation in patients with chronic constipation, gastroparesis, functional dyspepsia. Aim: To investigate whether an effective procedure IBS patients. Methods: were randomly placed vacuum interferential (IFC) placebo groups....

10.1159/000338301 article EN Digestion 2012-01-01

Ulcerative colitis (UC) is a chronic inflammatory disease characterized by recurrent inflammation and ulcerations of colonic mucosa an inappropriate delayed healing. Adenosine deaminase (ADA) cytoplasmic enzyme involved in the catabolism purine bases, capable catalyzing deamination adenosine, forming inosine result process. Although ADA has been shown to increase several conditions, there are no literature data indicating alteration UC.This study evaluated activity total serum 43 patients...

10.1016/j.crohns.2011.07.010 article EN Journal of Crohn s and Colitis 2011-08-19

There are several studies reporting the beneficial effects of transcutaneous electrical stimulation in patients with gastroparesis and chronic constipation.To analyse whether is an effective procedure functional dyspepsia patients.Functional were randomly placed vacuum interferential current (IFC) placebo groups. Both treatments consisted 12 sessions administered over 4 weeks. Upper gastrointestinal system symptoms documented at beginning, during after treatment sessions.Patients therapy (23...

10.1111/j.1365-2036.2010.04256.x article EN Alimentary Pharmacology & Therapeutics 2010-02-05

Background: Our aim was to document the frequency of gastrointestinal (GI) involvement Behçet’s disease (BD) at endoscopic examination. Also, we aimed analyze whether GI lesions were correlated with other systemic components BD. Methods: Fifty patients BD enrolled in study. Patients whom optimal colonoscopic examination both colon and terminal ileum could be performed included. An biopsy taken from all cases. Upper endoscopy findings, presence genital ulcers, uveitis, dermatological lesions,...

10.1159/000264643 article EN Digestion 2010-01-01

Visfatin is a peptide that secreted from visceral fat. It has been reported to be associated with inflammation and endothelial dysfunction. However, little known about its function in hypertension. Therefore the aim of present study was evaluate visfatin levels patients hypertension.We studied forty-six newly diagnosed hypertensive 30 healthy participants. In accordance blood pressure JNC 7 guidelines, were divided into 2 groups: stage 1 2. The control group normal prehypertensive. Blood...

10.2169/internalmedicine.51.6609 article EN other-oa Internal Medicine 2012-01-01

Objective Irritable bowel syndrome (IBS) is a highly prevalent and debilitating functional disorder. The toll-like receptors (TLRs) are family of pathogen-recognition in the innate immune system. In present study we aimed to investigate TLR2, TLR4 nitric oxide (NO) levels patients with IBS. Methods Fifty-one IBS 15 healthy controls were included study. Colonic tissue NO detected using an enzyme-linked immunosorbent assays (ELISA) through biochemical methods. Results colonic significantly...

10.2169/internalmedicine.55.5716 article EN Internal Medicine 2016-01-01

Ankaferd Blood Stopper (ABS) is an herbal extract that enhances mucosal healing. The aim of this study was to investigate the efficacy ABS on healing esophagus and prevention stricture development after esophageal caustic injuries in rats. included 50 Rats were divided into five groups: group 1 (no injury, sham surgery), 2 (injury + no weeks injury), 3 4 5 injury). Standard burn injury created by applying 50% NaOH solution distal about 1.5 cm. To rats group, isotonic given instead NaOH. (2...

10.1111/j.1442-2050.2011.01231.x article EN Diseases of the Esophagus 2011-08-05

Recently, role of adipokin in the pathogenesis nonalcoholic fatty liver disease (NAFLD) has been suggested. Among adipokins, leptin and adiponectin is rather well known; however, there are only a few data concerning visfatin.NAFLD confirmed 30 patients by ultrasonography. As control group, without or other diseases were included. Viral hepatitis, metabolic diseases, autoimmune hepatitis consumption alcohol excluded all patients. Fasting serum level visfatin was determined ELISA method.Serum...

10.1002/jcla.21491 article EN Journal of Clinical Laboratory Analysis 2012-02-01

Background/Aim: Ankaferd blood stopper (ABS) is a herbal extract that enhances mucosal healing. In this study, we aimed to investigate the efficiency of ABS in treatment experimental distal colitis. Materials and Methods: Twenty one male albino rats were divided into three groups: Sham control (Group 1), colitis induced by acetic acid treated with saline 2), 3). At end 7th day induction, all lightly anesthetized intramuscular ketamine (8 mg/kg) thereafter laparotomy total colectomy...

10.4103/1319-3767.111955 article EN cc-by-nc-sa Saudi Journal of Gastroenterology 2013-01-01
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