Hikmet Fırat

ORCID: 0000-0003-2594-4887
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About
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Research Areas
  • Obstructive Sleep Apnea Research
  • Neuroscience of respiration and sleep
  • Cardiovascular and Diving-Related Complications
  • Sleep and Wakefulness Research
  • Sleep and related disorders
  • Tracheal and airway disorders
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Ocular Surface and Contact Lens
  • EEG and Brain-Computer Interfaces
  • Dysphagia Assessment and Management
  • Cardiovascular Disease and Adiposity
  • Restless Legs Syndrome Research
  • Restraint-Related Deaths
  • Inflammatory Biomarkers in Disease Prognosis
  • Sleep and Work-Related Fatigue
  • Lung Cancer Treatments and Mutations
  • Respiratory Support and Mechanisms
  • Cardiovascular Health and Disease Prevention
  • Vestibular and auditory disorders
  • S100 Proteins and Annexins
  • Nasal Surgery and Airway Studies
  • Allergic Rhinitis and Sensitization
  • Cerebral Venous Sinus Thrombosis
  • Advanced Sensor and Energy Harvesting Materials
  • Cleft Lip and Palate Research

Dışkapı Yıldırım Beyazıt Eğitim ve Araştırma Hastanesi
2013-2023

Sağlık Bilimleri Üniversitesi
2018-2023

W. L. Gore & Associates (Germany)
2022

Balıkesir University
2022

Ministry of Health
2009-2021

Hacettepe University
2016-2020

Kafkas University
2020

Marmara University
2018

Ankara Atatürk Göğüs Hastalıkları Ve Göğüs Cerrahisi Eğitim Ve Araştırma Hastanesi
2010-2018

Başkent University
2017

The prevalence of insomnia is influenced by environmental factors. This study aimed to investigate the and its sociodemographic clinical correlates in a general population-based survey Turkey.This included 4758 subjects among 5021 who participated Turkish Adult Population Epidemiology Sleep Disorders study. Questionnaire items evaluating were adapted from International Classification II DSM-IV-TR. Subjects with restless legs syndrome excluded.Insomnia was found be associated older age (18-24...

10.1111/pcn.12252 article EN Psychiatry and Clinical Neurosciences 2014-11-11

To predict the validity of Watch-PAT (WP) device for sleep disordered breathing (SDB) among highway bus drivers.A total number 90 drivers have undergone polysomnography (PSG) and test simultaneously. Routine blood tests routine ear-nose-throat (ENT) exams been done as well.The sensitivity, specificity, positive predictive value (PPV) negative (NPV) were 89.1%, 76.9%, 82% 85.7% RDI > 15, respectively. WRDI, WODI, W < 90% duration Wmean SaO2 results well correlated with PSG results. In...

10.5664/jcsm.2584 article EN Journal of Clinical Sleep Medicine 2013-04-12

Sleep disorders constitute an important public health problem. Prevalence of sleep in Turkish adult population was investigated a nationwide representative sample 5021 adults (2598 women and 2423 men, response rate: 91%) by interviewer-administered questionnaire. Insomnia defined the DSM-IV criteria, habitual snoring risk for sleep-related breathing (SDB) Berlin questionnaire, excessive daytime sleepiness (EDS) Epworth scale score, restless legs syndrome (RLS) complaints according to...

10.1111/sbr.12118 article EN cc-by-nc-nd Sleep and Biological Rhythms 2015-04-09

Inflammation is one of the pathophysiological pathways suggested for development cardiovascular disease in obstructive sleep apnea (OSA). The recurrent nocturnal episodes hypoxia/reoxygenation observed patients with OSA appear to be partly responsible systemic inflammatory response. aim this study was investigate role inflammation by measuring C-reactive protein (CRP) and fibrinogen levels, erythrocyte sedimentation rate (ESR) according gender. This included 139 apparently healthy subjects...

10.2174/18715230113129990015 article EN Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry 2014-01-31

To investigate the cross-sectional association between serum adipocyte fatty acid-binding protein (A-FABP) level and diagnosis or severity of obstructive sleep apnea syndrome (OSAS) some echocardiographic indices related with cardiac dysfunction.In this study, plasma A-FABP high-sensitivity C-reactive concentrations were measured, echocardiography was performed in subjects without any pulmonary disease who referred for evaluation OSAS. According to apnea-hypopnea index (AHI), classified into...

10.2310/jim.0b013e31826868f2 article EN Journal of Investigative Medicine 2012-10-01

Obstructive sleep apnea (OSA) has been shown to be associated with atrial fibrillation (AF). Prolongation of inter- and intraatrial conduction times during sinus rhythm also related AF generation. Nasal continuous positive airway pressure (CPAP) is an effective treatment modality OSA.Twenty-four OSA patients diagnosed through polysomnography 18 controls were included in the study. The basal electromechanic delays prior onset therapy measured using tissue Doppler imaging. P-wave dispersion...

10.1111/anec.12106 article EN Annals of Noninvasive Electrocardiology 2013-11-05

Obstructive sleep apnea (OSA) has long been suggested to increase the risk of development autoimmune diseases. We investigated prevalence Hashimoto's thyroiditis (HT) in 245 euthyroid individuals, who were suspected having OSA. After polysomnography, subjects grouped according apnea-hypopnea index (AHI) consecutively as controls (n=27F/32M, AHI<5), mild-OSA (n=22F/37M, 5≤AHI<15), moderate-OSA (n=23F/38M, 15≤AHI<30) and severe-OSA (n=30F/36M, AHI≥30). Diagnosis HT based on thyroid ultrasound...

10.1507/endocrj.ej12-0106 article EN Endocrine Journal 2012-01-01

Reactive oxygen species produced either endogenously or exogenously can attack lipids, proteins and DNA in human cells cause potentially deleterious consequences. In recent years, their role the pathogenesis of lung cancer preventive effect antioxidants have been studied extensively. this study, our aim was to investigate levels 8-hydroxy-2'-deoxyguanosine (8OHdG) malondialdehyde as a marker for effects reactive on antioxidant vitamins correlations between these oxidative stress markers...

10.1515/cclm.2008.010 article EN Clinical Chemistry and Laboratory Medicine (CCLM) 2008-01-01

We used electrophysiological measures to investigate the effects of obstructive sleep apnea on attention, learning, and memory. Thirty subjects (OSA group, n = 15, control group 15) participated in n-back tests, accompanied by P300 recordings, working memory attention. The mirror-drawing test was study procedural memory, trail-making (TMT) evaluate divided attention executive function. No significant difference reaction time found 0-back 1-back tests. In 2-back test, times patients were...

10.1371/journal.pone.0090647 article EN cc-by PLoS ONE 2014-02-28

Abstract Introduction This study was conducted to investigate the relationship between sleep quality ( SQ ) and disease activity DA in patients with ankylosing spondylitis AS evaluate response anti‐tumor necrosis factor α (anti‐ TNF ‐α) therapy on disorders. Materials Methods A total of 34 who met modified New York classification criteria for were included this prospective study. Patients divided into two groups as follows: Group I n = 15) high receiving anti‐ ‐α therapy, II 19) remission....

10.1111/1756-185x.13102 article EN International Journal of Rheumatic Diseases 2017-05-29

Objective: To investigate the effect of one year continuous positive airway pressure (CPAP) treatment on metabolic syndrome (MS) prevalence and components in patients diagnosed with both obstructive sleep apnea (OSAS) syndrome.Methods: This was a single center, observational prospective cohort study. 38 who were OSAS after polysomnographic analysis laboratory MS according to National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) guideline underwent CPAP followed for...

10.1179/acb.2009.051 article EN Acta Clinica Belgica 2009-08-01
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