A5045607605- Poisoning and overdose treatments
- Herpesvirus Infections and Treatments
- Mechanical Circulatory Support Devices
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Antibiotics Pharmacokinetics and Efficacy
- Antifungal resistance and susceptibility
- Cardiac Arrest and Resuscitation
- Kawasaki Disease and Coronary Complications
- Alcoholism and Thiamine Deficiency
- Vitamin K Research Studies
- Blood transfusion and management
- Blood disorders and treatments
- Electrolyte and hormonal disorders
- Drug-Induced Hepatotoxicity and Protection
- Coronary Artery Anomalies
- Neurological Complications and Syndromes
- Obstructive Sleep Apnea Research
- Hemoglobinopathies and Related Disorders
- Cerebral Venous Sinus Thrombosis
- Bacterial Identification and Susceptibility Testing
- Respiratory Support and Mechanisms
- COVID-19 Clinical Research Studies
- Gout, Hyperuricemia, Uric Acid
- Neonatal Respiratory Health Research
- Blood Coagulation and Thrombosis Mechanisms
University of Lausanne
2018-2024
University Hospital of Lausanne
2019-2024
The University of Melbourne
2023
Murdoch Children's Research Institute
2023
Intensive Care Society
2019
Hôpital Orthopédique de la Suisse Romande
2011
Houston Methodist
1998
Methodist Hospital
1998
BackgroundThe benefits of facilitating breastmilk feeding and close contact between mother neonate (family-centred care; FCC) in the perinatal period are well-established. The aim this study was to determine how delivery FCC practices were impacted for neonates born mothers with SARS-CoV-2 infection during COVID-19 pandemic.MethodsNeonates confirmed pregnancy identified from 'EsPnIC Covid paEdiatric NeonaTal REgistry' (EPICENTRE) multinational cohort 10 March 2020 20 October 2021. EPICENTRE...
Panton-Valentine leucocidin producing methicillin-resistant Staphylococcus aureus infections are rare but associated with very high mortality rates. We report the case of a 14-year-old patient infection and Influenza B pneumonia requiring veno-arterial extra-corporeal membrane oxygenator for refractory shock. In absence response to conventional therapy, we have inserted Cytosorb® cartridge within circuit. A spectacular decrease in vasopressor requirements followed. Since clindamycin, key...
Abstract In this article, we presented a teenager, in maintenance chemotherapy for leukemia, who was admitted digestive symptoms related to parasitic infection and required nutritional support with parenteral nutrition. After 6 weeks, his condition worsened refractory shock of presumed septic origin, necessitating extracorporeal membrane oxygenation. Despite hemodynamic stabilization, lactic acidosis until thiamine supplementation started. Lactate normalized within 12 hours. Thiamine is an...
Colchicine poisoning is associated with a poor prognosis, especially when leading to shock and multi-organ failure, management limited supportive care, including multiple-dose activated charcoal. At therapeutic concentrations, colchicine elimination occurs mainly through hepatic metabolism involves an enterohepatic circulation, small contribution of renal (10–30%). toxicokinetics however rarely described, in children. We present the case 4-year-old patient who survived severe iatrogenic...
Refractory cardiogenic and vasoplegic shock after congenital heart surgery is a threatening condition leading to high morbidity mortality. Control of hemodynamic inflammatory response fundamental in medical strategy. We report the case newborn with secondary cardiopulmonary bypass for atrioseptostomy prostaglandin treatment context hypoplastic left syndrome, successfully treated combination mechanical circulatory support cytokine hemoadsorption column (CytoSorb®). Vasopressor was weaned...
A 73-days old infant of 34 weeks' gestation was hospitalized with a co-infection respiratory syncytial virus (RSV) and Bordetella pertussis (BP). She required invasive ventilation for 9 days in the context malignant persistent hypoxemia hypercapnia secondary to leukemoid reaction. Despite an increase white blood cell (WBC) count up 70 G/L ensuing pulmonary hypertension, no hemodynamic compromise occurred. Without clear indication leukapheresis nor exchange transfusion, off-label treatment...
Reversible cerebral vasoconstriction syndrome (RCVS) is a vascular disease characterized by diffuse transient and vasodilatation of the arteries. It commonly associated with recurrent severe acute headaches or without focal neurological deficits due to hemorrhages, infarcts, even posterior reversible encephalopathy syndrome. The optimal management neurologic caused RCVS still uncertain. Calcium channel blockers (CCBs) such as nimodipine verapamil have been reported be effective in adult...
Previous findings from the Swissped RECOVERY trial showed that patients with Pediatric Inflammatory Multisystem Syndrome-Temporally Associated SARS-CoV-2 (PIMS-TS) who were randomly assigned to intravenous immunoglobulins or methylprednisolone have a comparable length of hospital stay. Here, we report 6-month follow-up outcomes cardiac pathologies and normalisation clinical laboratory signs inflammation this study population.This pre-planned PIMS-TS included Trial reports on cohort after...
Viscoelastic tests and impedance aggregometry allow coagulation evaluation at the bedside, but reference values are scarce in pediatrics. The aim of this study was to establish thromboelastometry for population compare it between age groups. This prospective, single-center, observational evaluates viscoelastic children with congenital heart disease. A total 204 were included a median 3.6 years old. We provide references median, percentile 2.5 97.5. Infants demonstrate extrinsic activity...
In this article, we reported the case of a child patient who was admitted to our PICU for severe acute respiratory distress syndrome (ARDS) while being treated with trimethoprim-sulfamethoxazole (TMP-SMX) osteomyelitis. Based on timing exposure, lack alternative explanations, and clinical course similar previously described cases, suspect that TMP-SMX may have triggered ARDS. Despite meeting criteria extracorporeal membrane oxygenation cannulation, conservative management lung recruitment...
Children with cyanotic congenital heart diseases have a higher risk of bleeding or thrombosis. Rotational thromboelastometry, using tissue factor (EXTEM), contact activator (INTEM), cytochalasin (FIBTEM), assesses coagulation by determining the time to initiation clotting (CT) and clot firmness (MCF), including platelet-fibrin-interaction. This study aimed evaluate rotational thromboelastometry whole blood impedance aggregometry in (CCHD) compared control group without chronic cyanosis...
Neonatal linear immunoglobulin A (IgA) bullous dermatosis (NLABD) is a rare, life-threatening, mucocutaneous disorder. The pathogenesis and optimal treatment remain poorly defined raise critical clinical challenges.
Abstract Background Chloroquine use has increased worldwide recently in the setting of experimental treatment for novel coronavirus disease (Covid-19). Nevertheless, case chloroquine intoxication, it can be life threatening, with cardiac arrest, due to its toxicity. Case presentation This study reports on a 14-years-old girl who presented arrest after an uncommon suicide attempt by ingesting 3 g chloroquine. After 66 min cardio-pulmonary resuscitation (CPR), extracorporeal cardiopulmonary...
Hallermann-Streiff syndrome (HSS) is a rare congenital with different anomalies including midface hypoplasia, beak nose and micrognathia. The upper airways narrowness can lead to severe respiratory complications such as obstructive sleep apnoea (OSAS), particularly in infancy. management of these OSAS difficult poorly documented literature. We report the case an infant HSS complicated by early successfully managed non-invasive ventilation (NIV), provide overview morbidities discuss treatment...
From the Department of Internal Medicine, Methodist Hospital Indiana, Indianapolis, Indiana Address for correspondence: Thomas G. Ferry, M.D., I-65 at 21st Street, P.O. Box 1367, IN 46206-1367
From the Department of Internal Medicine, Methodist Hospital Indiana, Indianapolis, Indiana Address for correspondence: Thomas G. Ferry, M.D., I-65 at 21st Street, P.O. Box 1367, IN 46206-1367