A5101672976- Kawasaki Disease and Coronary Complications
- Mechanical Circulatory Support Devices
- Streptococcal Infections and Treatments
- Non-Invasive Vital Sign Monitoring
- COVID-19 Impact on Reproduction
- Neonatal Respiratory Health Research
- Hemoglobinopathies and Related Disorders
- COVID-19 Clinical Research Studies
- Educational Environments and Student Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Dermatological and COVID-19 studies
- Coronary Artery Anomalies
- SARS-CoV-2 and COVID-19 Research
- Dupuytren's Contracture and Treatments
- Ovarian function and disorders
- Latin American Urban Studies
- Venous Thromboembolism Diagnosis and Management
- Liver Disease and Transplantation
- Atrial Fibrillation Management and Outcomes
- Elbow and Forearm Trauma Treatment
- Diagnosis and Treatment of Venous Diseases
- Ultrasound in Clinical Applications
- Respiratory Support and Mechanisms
- Liver Disease Diagnosis and Treatment
- Bone fractures and treatments
University of Basel
2022-2025
University Children’s Hospital Basel
2022-2025
Riverside Methodist Hospital
2023
The impact of hydroxyurea (HU) on the ovarian reserve female patients with sickle cell disease (SCD) remains poorly elucidated. Only direct histological analysis follicle density can effectively evaluate HU's effect reserve. By analyzing digitized slides tissue from girls and young women SCD who underwent cryopreservation (OTC) before hematological stem transplantation, we meticulously counted follicles categorized them based their growth stage. We then calculated densities different types...
We evaluated whether sample entropy of heart rate time series could serve as a biomarker for guiding caffeine cessation in preterm infants treated apnoea prematurity (AOP). also assessed associations with weeks gestation, clinical morbidity, AOP frequency and reinitiation. conducted prospective single-centre study at the University Children's Hospital Basel, Switzerland, from July 2019 to June 2020. included 61 hospitalised born before 32 gestation. Heart was derived standard monitoring...
Bronchopulmonary dysplasia (BPD) is the most common respiratory complication after preterm birth. Early preventive measures are important to reduce further damage on lung tissue. Thus, early discrimination between infants with and without BPD of high importance. A low sample entropy (SampEn) time series oxyhemoglobin saturation (SpO2-SampEn for short) associated an increased risk hypoxemic events in neonates. We hypothesized that have a lower SpO2-SampEn compared term infants. Moreover,...
Introduction In 2020, a new disease entitled Pediatric Inflammatory Multisystem Syndrome temporally associated with COVID-19 (PIMS-TS), or in Children (MIS-C), emerged, thousands of children affected globally. There is no available evidence based on randomized controlled trials (RCT) to date the two most commonly used immunomodulatory treatments, intravenous immunoglobulins (IVIG) and corticosteroids. Therefore, Swissped RECOVERY trial was conducted assess whether (IV) methylprednisolone...
Previous findings from the Swissped RECOVERY trial showed that patients with Pediatric Inflammatory Multisystem Syndrome-Temporally Associated SARS-CoV-2 (PIMS-TS) who were randomly assigned to intravenous immunoglobulins or methylprednisolone have a comparable length of hospital stay. Here, we report 6-month follow-up outcomes cardiac pathologies and normalisation clinical laboratory signs inflammation this study population.This pre-planned PIMS-TS included Trial reports on cohort after...
Conventional X-ray imaging for fracture diagnosis is time-consuming and exposes patients to ionizing radiation. Additionally, the positioning of injured limb standardized painful. Point-of-care ultrasound (POCUS) increasingly available in medical offices emergency rooms. This study aimed prove non-inferiority POCUS compared with respect diagnostic sensitivity, pain, investigation time long-bone fractures upper extremity children. Children adolescents (1−18 years old) presenting UKBB service...
Data on COVID-19 vaccine acceptability among parents of children with multisystem inflammatory syndrome (MIS-C) are limited. In this cohort MIS-C, enrolled in the Swissped RECOVERY trial (NCT 04826588), comparing intravenous immunoglobulins or methylprednisolone, who, accordance Swiss guidelines, were recommended for SARS-CoV-2 vaccination, 65% (73/112) reported being vaccinated against before while 70% after MIS-C episode their child. None occurrence and only 9% (5/56) received MIS-C. The...
Variceal bleeding (VB) is one of the main causes morbidity and mortality associated with portal hypertension (PHT) complications in patients liver cirrhosis. There scarce information from South America on frequency, primary prophylaxis treatment this complication. This study aimed to know frequency VB as first cause decompensation cirrhosis, describe management VB. We conducted a retrospective cohort that included 1061 8 centers five American countries. Data medical records collected...
In trials of acute severe infections or inflammations frequent administration non-randomised treatment (ie, intercurrent event) in response to clinical events is expected. These may affect the interpretation trial findings. Swissped-RECOVERY was set up as one first randomised controlled worldwide, investigating comparative effectiveness anti-inflammatory with intravenous methylprednisolone immunoglobulins children and adolescents Paediatric Inflammatory Multisystem Syndrome Temporally...
Abstract Background PIMS-TS presents with features considered to pose a risk for the development of unfavourable long-term mental health outcomes which haven’t been prospectively investigated. These include neurological symptoms (headache, confusion, and delirium), systemic inflammation, critical illness requiring PICU support. Therefore, we set out investigate at 6-month follow-up in patients recruited into Swissped-RECOVERY trial. Methods This is pre-planned analysis trial...
This paper contains the second stage of research "The minimum area required for children aged between 3 and 5 years old in a kindergarten", which was developed Buen Comienzo Programme, Medellin’s Municipality Architects Julie Waldron Ader Garcia. Often, kindergarten are planned conventional way construction; they designed following standard building measurements (NTC4595), given by quantity square meters per child, rather than spatial necessities. Therefore, aim this to evaluate occupation...